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Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Study assesses global discrepancies in COVID-19 management guidelines across WHO member states, revealing that many national guidelines do not fully align with WHO recommendations, especially in lower-resource countries.

23 Apr 2024

Analysis finds significant variations in national COVID-19 treatment recommendations

National clinical guidelines for the treatment of COVID-19 vary significantly around the world, with under-resourced countries the most likely to diverge from gold standard (World Health Organization; WHO) treatment recommendations, finds a comparative analysis published in the open access journal BMJ Global Health.

23 Apr 2024

Study reveals how SARS-CoV-2 hijacks lung cells to drive COVID-19 severity

Researchers identified how SARS-CoV-2 targets and manipulates specific lung cells, using innovative techniques to trace the virus's impact on the cells' gene expression, revealing insights into early COVID-19 pathogenesis.

14 Apr 2024

Molnupiravir influences SARS-CoV-2 evolution in immunocompromised patients

Study found that the antiviral molnupiravir affects the evolution of SARS-CoV-2 in immunocompromised patients, suggesting its use modifies viral mutation patterns and may impact viral evolution.

25 Mar 2024

Nirmatrelvir treatment shows no link to reduced long-COVID risk, study reveals

Recent study reveals nirmatrelvir treatment during acute COVID-19 does not lower the risk of post-acute COVID-19 symptoms, nor is it associated with symptomatic rebound.

8 Jan 2024

WHO experts update guidance on COVID-19 treatments

A panel of international experts representing the World Health Organization's Guideline Development Group has updated its guidance on treatments for patients with covid-19.

9 Nov 2023

Omicron variant BA.2.86 spreads faster, but current antivirals hold the line

Researchers discover the BA.2.86 Omicron lineage with higher transmission potential than current dominant strains, yet show that existing antivirals remain effective. Despite its higher infectivity, BA.2.86 exhibits lower pathogenicity in hamsters, indicating decreased replication capacity may lead to less severe infections.

7 Nov 2023

Virginia Tech researchers develop new drug design framework to fight COVID-19

As the COVID-19 pandemic scattered and isolated people, researchers across Virginia Tech connected for a data-driven collaboration seeking improved drugs to fight the disease and potentially many other illnesses.

19 Oct 2023

AI-powered patient triage platform predicts COVID-19 severity and length of hospitalization

A team of researchers from Yale University and other institutions globally has developed an innovative patient triage platform powered by artificial intelligence (AI) that the researchers say is capable of predicting patient disease severity and length of hospitalization during a viral outbreak.

29 Aug 2023

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Researchers investigated whether anti‑interleukin 6 monoclonal antibodies were related to heterogenous treatment effects between male and female COVID-19 patients.

24 Aug 2023

Proxalutamide shows promise as potential COVID-19 treatment

At the outset of the COVID pandemic, men appeared to suffer higher rates of severe illness and death, leading researchers to suspect a link between androgen receptors-;which bind to hormones like testosterone--and SARS-CoV-2 viral infection.

18 Aug 2023

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Researchers report that convalescent plasma treatment is most effective in treating hospitalized COVID-19 patients.

17 Aug 2023

Intranasal inoculation study sheds light on nasal and systemic immune responses to SARS-CoV-2

Study reveals the events accompanying the COVID-19 infection cascade in the nasal mucosa and free circulation

1 Aug 2023

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

Researchers identified the anti-SARS-CoV-2 function of phospholipid scramblase 1 (PLSCR1).

14 Jul 2023

IL-9 identified as contributor to viral spread and airway inflammation in COVID-19

Researchers used a K18-hACE2 transgenic (ACE2.Tg) mouse model to demonstrate that interleukin-9 (IL-9).

13 Jul 2023

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis. William G. Powderly, MD, (right) who led the large clinical trial, discusses patient conditions with Maanasi Samant, MD, in the intensive care unit at Barnes-Jewish Hospital, one of the major trial sites, during the COVID-19 pandemic.

10 Jul 2023

Remdesivir News and Research

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Analysis finds significant variations in national COVID-19 treatment recommendations

Study reveals how SARS-CoV-2 hijacks lung cells to drive COVID-19 severity

Molnupiravir influences SARS-CoV-2 evolution in immunocompromised patients

Nirmatrelvir treatment shows no link to reduced long-COVID risk, study reveals

WHO experts update guidance on COVID-19 treatments

Omicron variant BA.2.86 spreads faster, but current antivirals hold the line

Virginia Tech researchers develop new drug design framework to fight COVID-19

AI-powered patient triage platform predicts COVID-19 severity and length of hospitalization

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Proxalutamide shows promise as potential COVID-19 treatment

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Intranasal inoculation study sheds light on nasal and systemic immune responses to SARS-CoV-2

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

IL-9 identified as contributor to viral spread and airway inflammation in COVID-19

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Prior exposure to air pollutants and black carbon load predicts outcomes in hospitalized COVID-19 patients

Molecular insights into long COVID: serum proteome reveals dominant signaling pathways

Using heart and lung stem cells to better understand how COVID-19 impacts different organs

When COVID meets Candida: exploring the alarming surge of C. auris in Israel

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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