Renin News and Research

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Renin, also known as angiotensinogenase, is an enzyme that participates in the body's renin-angiotensin system (RAS) that mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. Thus, it regulates the body's mean arterial blood pressure.

Long-term consumption of lingonberry juice lowers high blood pressure, study finds

An experimental study found that long-term consumption of lingonberry juice lowers high blood pressure and improves the function of blood vessels.

3 Jan 2020

Father’s nutritional pattern affects child’s cardiovascular health

While couples often change their lifestyle in order to conceive faster, including crash diets, a new study in mice throws up the possibility that this kind of extreme dietary modification by the father might result in adverse effects on the child conceived in this manner.

17 Oct 2019

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel.

15 Oct 2019

New drug Aliskiren shows promise for heart failure patients

A study published in the International Journal of Molecular Sciences, as part of a special issue “Heart Failure: From Molecular Basis to Therapy”, in August 2019, shows that aliskiren, a drug approved by the US Food and Drug Administration (FDA), can improve survival for over 5 years, on average, and enhance life quality in patients who have been correctly diagnosed with heart failure.

9 Oct 2019

Aliskiren drug can delay progression of congestive heart failure, lengthen survival rates

Researchers at the University of Arizona College of Medicine - Phoenix have shown for the first time in preclinical studies that Aliskiren, a drug that inhibits the enzyme that regulates blood pressure, can delay the progression of congestive heart failure and lengthen survival rates.

8 Oct 2019

Physiologists, researchers to discuss factors underlying cardiovascular disease at APS conference

International physiologists and researchers studying the kidney, high blood pressure and related medical conditions will convene next week at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.

25 Sep 2019

ARNI therapy trial misses target in heart failure, may have selective benefit only

Heart failure with preserved ejection fraction (HFpEF) is a common condition, affecting millions of people and resulting in significant illness and death. No effective treatments have been developed for this condition.

2 Sep 2019

Disease-modifying therapy for Alport syndrome still remains an unmet need

Alport syndrome is a hereditary type IV collagen disease that leads to progressive proteinuria, renal fibrosis, and kidney failure.

13 Jun 2019

Study suggests new approach to treat renal fibrosis

Renal fibrosis, the abnormal accumulation of fibrotic material within the kidney, hinders kidney function and may lead to eventual renal failure.

16 Apr 2019

Drug lowers kidney failure risk in diabetic patients, study finds

A new landmark clinical trial shows that a drug lowers the risk of kidney failure by a third in people with Type 2 diabetes and kidney disease.

15 Apr 2019

Low-salt diet may be more beneficial for females than males

A low-salt diet may be more beneficial in lowering blood pressure in females than males, report scientists who found that while actual salt retention isn't higher in females, there is still an effect that drives pressure up.

11 Dec 2018

D-serine produced by gut microbiota protects against acute kidney injury, show study

The kidney is an organ not only for excreting body waste by urine but also for maintaining body homeostasis in close cooperation with other organs.

27 Nov 2018

Newly designed mice emulate severe form of kidney damage in humans with diabetes

Scientists led by Duke-NUS Medical School have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy.

9 Nov 2018

Academics receive prestigious awards for achievements in blood pressure research

Two academics from Queen Mary University of London have received prestigious awards from the International Society of Hypertension 2018 in recognition of their achievements in blood pressure research.

24 Sep 2018

New statement provides detailed overview of how to diagnose, treat resistant hypertension

Resistant hypertension affects 12 percent to15 percent of patients treated for high blood pressure according to a new scientific statement from the American Heart Association.

14 Sep 2018

$Entresto drug can be initiated early and safely in heart failure patients with reduced ejection fraction$

Entresto drug can be initiated early and safely in heart failure patients with reduced ejection fraction

Data from the TRANSITION study presented today at the European Society of Cardiology Congress in Munich, Germany has shown that Entresto® can be initiated early and safely in a wide range of heart failure patients with reduced ejection fraction who have been stabilized after hospitalization due to an acute heart failure episode.

25 Aug 2018

Renin News and Research

Further Reading

Long-term consumption of lingonberry juice lowers high blood pressure, study finds

Father’s nutritional pattern affects child’s cardiovascular health

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

New drug Aliskiren shows promise for heart failure patients

Aliskiren drug can delay progression of congestive heart failure, lengthen survival rates

Physiologists, researchers to discuss factors underlying cardiovascular disease at APS conference

ARNI therapy trial misses target in heart failure, may have selective benefit only

Disease-modifying therapy for Alport syndrome still remains an unmet need

Study suggests new approach to treat renal fibrosis

Drug lowers kidney failure risk in diabetic patients, study finds

Low-salt diet may be more beneficial for females than males

D-serine produced by gut microbiota protects against acute kidney injury, show study

Newly designed mice emulate severe form of kidney damage in humans with diabetes

Academics receive prestigious awards for achievements in blood pressure research

New statement provides detailed overview of how to diagnose, treat resistant hypertension

Entresto drug can be initiated early and safely in heart failure patients with reduced ejection fraction

Experimental compound reduces destructive inflammation to improve stroke outcome

Study reveals unexpected mechanism that induces thirst after alcohol or sugar exposure

Researchers uncover specific gene region in hypertension

Arterial stiffness improves with high doses of vitamin D supplementation, study finds

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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