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Cryo-electron microscopy reveals how membrane microdomains respond to mechanical stress

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood.

24 Jul 2024

Wearable devices can amplify anxiety in people with Afib

Using a wearable device, such as a smart watch, to track health data and symptoms, is supposed to help people monitor their health and address symptoms as quickly as possible to spur positive health outcomes.

24 Jul 2024

WashU study reveals key mechanisms of biological clocks

In humans and other animals, signals from a central circadian clock in the brain generate the seasonal and daily rhythms of life.

24 Jul 2024

Retinoblastoma therapy evolves with higher success rates and lower complications

The evolution of retinoblastoma treatment over the past 15 years has resulted in a higher likelihood of vision preservation without compromising survival, according to research released today at the Society of NeuroInterventional Surgery's (SNIS) 21st Annual Meeting.

24 Jul 2024

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

High-risk NSAID prescriptions cost NHS £31 million

Prescribing non-steroidal anti-inflammatory drugs (NSAIDs) to people at high risk of harm from them is estimated to cost the NHS in England around £31 million and cause more than 6,000 lost years of good health over 10 years, finds a study published by The BMJ today.

24 Jul 2024

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Indiana University School of Medicine researchers have made a significant breakthrough in developing a new gene therapy approach that restores full-length dystrophin protein, which could lead to new treatments for people with Duchenne muscular dystrophy (DMD).

24 Jul 2024

High belly and arm fat linked to Alzheimer's and Parkinson's risk

People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer's and Parkinson's than people with low levels of fat in these areas, according to a study published in the July 24, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

24 Jul 2024

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Researchers in George Mason University's Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study in Nature's Gene Therapy that found an HIV-like virus particle that could cease the need for lifelong medications.

24 Jul 2024

Older adults show interest in deprescribing, study reveals

More than 82% of Americans age 50 to 80 take one or more kinds of prescription medication, and 80% of them say they'd be open to stopping one or more of those drugs if their health care provider gave the green light, a new University of Michigan study shows.

24 Jul 2024

Breakthrough in acute myeloid leukemia treatment targets stem cells

Acute myeloid leukemia is one of the deadliest cancers. Leukemic stem cells responsible for the disease are highly resistant to treatment.

24 Jul 2024

Simple blood test may predict CAR-T therapy success in multiple myeloma

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according to new research from Weill Cornell Medicine, NewYork-Presbyterian, Columbia University and Icahn School of Medicine at Mount Sinai.

24 Jul 2024

Neuroscientists discover a key piece of the placebo effect puzzle

The placebo effect is very real. This we've known for decades, as seen in real-life observations and the best double-blinded randomized clinical trials researchers have devised for many diseases and conditions, especially pain.

24 Jul 2024

'Gene misbehavior' found to be surprisingly common among the healthy population

Scientists have uncovered that 'gene misbehavior' – where genes are active when they were expected to be switched off – is a surprisingly common phenomenon in the healthy human population.

24 Jul 2024

CHEST releases new clinical guideline for managing central airway obstruction

The American College of Chest Physicians (CHEST) recently released a new clinical guideline on central airway obstruction (CAO).

24 Jul 2024

Reducing testing disparities could dramatically cut colon cancer rates among Black Americans

A new paper in the Journal of the National Cancer Institute, published by Oxford University Press, finds that eliminating the race disparity in colon cancer testing in the United States would reduce colon cancer, and colon cancer death rates, dramatically among Black people.

24 Jul 2024

New study helps better understand the pathology of fatty liver disease MASH

A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis.

24 Jul 2024

Community pharmacists help close gaps in stroke prevention for Afib patients

Atrial fibrillation (Afib) is the most common heart rhythm disorder encountered in clinical practice according to Dr. Roopinder Sandhu, MD, MPH, and the leading cause of stroke in older individuals.

24 Jul 2024

Traffic-related ultrafine particles impair mitochondrial function in human olfactory cells

Ultrafine particles, UFPs, the smallest contributors to air pollution, hinder the function of mitochondria in human olfactory mucosa cells, a new study shows.

24 Jul 2024

Children with psychiatric disorders face greater challenges today than in the past

Surveys conducted in England in 1999, 2004, and 2017 have revealed that children with a psychiatric disorder in 2017 experienced more severe difficulties and greater impacts on functioning at school, home, and in their daily lives, compared with children with a disorder in earlier decades.

24 Jul 2024