Respiratory News and Research

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Probability sampling to slow spread of SARS-CoV-2

Their study titled, “An Innovative Non-Pharmaceutical Intervention to Mitigate SARS-CoV02 Spread: Probability Sampling to Identify and Isolate Asymptomatic Cases,” was released at the pre-publication and pre-peer review site medRxiv*.

14 Oct 2020

A "five-day switch" plan for schools reopenings during COVID-19

Researchers worked on mathematical predictions that could predict the safety of reopening schools in the U.S. Their study titled, “Safely Reopening K-12 Schools During the COVID-19 Pandemic,” is published preprint at the website medRxiv.

14 Oct 2020

First confirmed US case of SARS-CoV-2 reinfection

Of the cases of reinfections worldwide, a particular case has been reported by scientists at the Nevada Institute of Personalized Medicine, University of Nevada. A 25-year-old man from Washoe County in the United States, the hardest-hit country globally, has more than 7.85 million cases.

14 Oct 2020

D614G mutation in SARS-CoV-2 increases viral fitness and infectivity

Researchers from the Duke Human Vaccine Institute and Duke University, Durham NC, USA, recently analyzed the D614G mutation in SARS-CoV-2 in the context of a soluble S ectodomain construct. Their study has been published in the preprint server bioRxiv.

14 Oct 2020

Children and teens can spread SARS-CoV-2 in their households

A team of researchers from the Georgia Department of Public Health and the U.S Centers for Disease Control and Prevention (CDC) aimed to determine the secondary attack rates (SAR) among household contacts of children and adolescents who contracted SARS-CoV-2 during an outbreak at an overnight camp in June.

13 Oct 2020

Pre-existing immunity to other coronaviruses may be poor

Brenda M. Westerhuis et al., in a recent medRxiv* preprint paper, investigate the antibody cross-reactivity - to explain the severe disease. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

13 Oct 2020

Salivary samples highly effective in detecting SARS-CoV-2

A team of scientists from the United States has found that oral salivary samples are less sensitive than nasal-oropharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA

13 Oct 2020

Mothers transmit passive protection against SARS-CoV-2 to their newborns

A recent study published on the preprint server medRxiv in October 2020 shows that newborns may be protected from acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by antibodies in the mother’s blood that travels through the placenta.

13 Oct 2020

Bacterial toxin stimulates tissue regeneration

Normally they are among the many harmless organisms found in and on the human body: one in four people have millions of Staphylococcus aureus bacteria on their skin and on the mucous membranes of the upper respiratory tract, without being aware of it.

13 Oct 2020

Drug derived from a natural human protein could stop lethal lung damage from the flu

The raging lung inflammation that can contribute to death from the flu can be stopped in its tracks by a drug derived from a naturally occurring human protein, a new animal study suggests.

13 Oct 2020

Are antibiotics being over prescribed in COVID-19?

A new study published on the preprint server medRxiv in October 2020 shows that the baseline levels of inflammatory markers and C-reactive protein (CRP) in relation to antibiotic administration can rule out bacterial co-infections and help reduce the unnecessary use of antibiotics.

13 Oct 2020

New computational approach improves characterization of cellular diversity

Researchers in the United States have developed a computational method called “weighted-nearest neighbor” (WNN) analysis that can significantly improve the ability to define cellular states across various biological contexts and data types.

13 Oct 2020

How SARS-CoV-2's spike protein highjacks the host cell trafficking machinery

Researchers at The Medical Research Council Laboratory of Molecular Biology have conducted a study showing how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein interacts with host cell factors in ways that promote the formation of syncytia.

13 Oct 2020

Researchers launch new clinical trial to investigate role of vitamin D against COVID-19

Researchers from Queen Mary University of London, funded by Barts Charity, have launched a new clinical trial to investigate whether taking vitamin D could protect people from COVID-19

13 Oct 2020

Researchers explore molecular factors that drive the severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

13 Oct 2020

Researchers call for nutritional guidelines and regulations on use of vitamin D

The professional perception of vitamin D as a medicine, rather than as a key nutrient, is constraining practice and jeopardizing the health of elderly care home residents in England, conclude researchers in the journal BMJ Nutrition Prevention & Health.

13 Oct 2020

COVID-19 vaccine candidate shows potent immune response

A COVID-19 vaccine candidate that underwent extensive preclinical testing at the University of Alabama at Birmingham this spring and summer shows potent preclinical immune responses -; including several that distinguish it from other COVID-19 vaccine approaches -; according to a preprint deposited in the BioRxiv repository this week.

13 Oct 2020

SARS-CoV-2 antibodies and COVID symptoms can last at least 3 months

Recent research published as a preprint on the medRxiv preprint server, Elizabeth T. Cirulli et al., studies the self-reported short and long-term symptoms in a large general adult population cohort.

13 Oct 2020

Scientists explain why some COVID-19 patients develop neurological symptoms

Now, a new study published on the preprint server bioRxiv sheds light on the mechanism behind brain involvement in the COVID-19 pandemic. A team of researchers at the Krembil Research Institute and the University of Toronto in Canada aimed to understand further the potential mechanisms underlying SARS-CoV-2 tropism for brain vasculature to see how infection occurs in the brain.

13 Oct 2020

Zinc deficiency linked to poor COVID-19 outcomes

A team of researchers from various universities and institutes in Spain recently published a paper on the preprint server medRxiv,* in which they hypothesize that serum zinc levels have a significant influence on COVID-19 progression and thus may be a useful biomarker in predicting severe disease in early stages of COVID-19 infection.

12 Oct 2020