Respiratory Tract Infections News and Research

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FDA approves cancer drug Afinitor for treatment of rare genetic disorder

The U.S. Food and Drug Administration approved the cancer drug Afinitor (everolimus) on Friday to treat patients with subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis (TS), a rare genetic disorder. This approval was for treatments of SEGA that can not be treated with surgery.

1 Nov 2010

Doctors misuse antibiotics to treat patients with respiratory tract infections: Study

Doctors frequently misuse antibiotics when treating patients hospitalized with respiratory tract infections (RTIs), according to a study to be published in the November issue of Infection Control and Hospital Epidemiology.

23 Sep 2010

Research Roundup: Disabled Medicare Enrollees' challenges; Increasing ER visits; costs/benefits of Part D

Health Affairs: Medicare Doesn't Work As Well For Younger, Disabled Beneficiaries As It Does For Older Enrollees - This paper examines "how well Medicare works for [the 8 million] nonelderly disabled beneficiaries compared to the elderly, based on findings from a nationally representative survey of noninstitutionalized Medicare beneficiaries conducted in 2008 by the Kaiser Family Foundation."

16 Aug 2010

Chimpanzee adenoviruses can be used as vaccine vectors: Research

In recent years, scientists have studied the possibility of using engineered human adenoviruses as vaccines against diseases such as HIV, tuberculosis, and malaria. In this approach, adenoviruses, which commonly cause respiratory-tract infections, are rendered relatively harmless before they are used as vectors to deliver genes from pathogens, which in turn stimulate the body to generate a protective immune response.

12 Aug 2010

Education, changes in reimbursement practices can reduce inappropriate antibiotic usage: Study

Improved drug coverage under Medicare Part D has led to an increase in the use of antibiotics by seniors, particularly of brand-name and more expensive drugs, according to a University of Pittsburgh Graduate School of Public Health study. Published in the Aug. 23 issue of Archives of Internal Medicine and the first to explore spending on antibiotics under Medicare Part D, the study suggests recent changes in drug coverage improved the use of antibiotics for pneumonia, but could lead to unnecessary spending on expensive broad-spectrum antibiotics and the overuse of inappropriate antibiotics.

11 Aug 2010

Study suggests reimbursements can address inappropriate antibiotic usage

Antibiotic use appears to have increased among older adults whose prescription drug coverage improved as a result of enrolling in Medicare Part D, with the largest increases for broad-spectrum, newer and more expensive drugs, according to a report in the August 9/23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

10 Aug 2010

Phase 3 U.S. registration study of LODOTRA shows improvement in patients with RA

Horizon Pharma, Inc., announced today that data from the Phase 3 U.S. registration study of LODOTRA, a circadian cytokine modulator and novel modified-release, low-dose prednisone tablet, showed a statistically significant improvement in American College of Rheumatology response criteria in patients with rheumatoid arthritis.

16 Jun 2010

Study examines survival rates of CF patients with MRSA

A team of researchers led by Elliott Dasenbrook, MD, MHS, Assistant Professor of Medicine and Pediatrics at Case Western Reserve University School of Medicine and Associate Director of the Adult Cystic Fibrosis Program at University Hospitals Case Medical Center's Rainbow Babies & Children's Hospital today published the findings from a major study about cystic fibrosis survival rates in the June 16 issue of JAMA.

16 Jun 2010

Vitamin D may help reduce incidence, severity of viral respiratory tract infections: Study

Vitamin D may help reduce the incidence and severity of viral respiratory tract infections including influenza, according to a new study conducted by investigators at Greenwich Hospital and Yale University School of Medicine.

16 Jun 2010

DanActive drink reduces rate of common sicknesses in daycare children, say researchers

The probiotic yogurt-like drink DanActive reduced the rate of common sicknesses such as ear infections, sinusitis, the flu and diarrhea in daycare children, say researchers who studied the drink in the largest known probiotic clinical trial to be conducted in the United States. An additional finding, however, showed no reduction in the number school days missed.

19 May 2010

Conservative therapies need to be recommended over routine use of OTC cough/cold products in children

Despite their widespread use by parents and caregivers, over-the-counter (OTC) cold and cough medicines have carried a warning by the FDA since 2008, and still have the potential to cause serious adverse events in infants and children. Conservative therapies, including nasal suctioning, humidification, and nasal saline, should be recommended over routine use of OTC cough/cold products in infants and children, according to a new commentary published in the May 2010 issue of Otolaryngology - Head and Neck Surgery.

4 May 2010

Conservative therapies recommended over routine use of OTC cough/cold products in children

Despite their widespread use by parents and caregivers, over-the-counter cold and cough medicines have carried a warning by the FDA since 2008, and still have the potential to cause serious adverse events in infants and children. Conservative therapies, including nasal suctioning, humidification, and nasal saline, should be recommended over routine use of OTC cough/cold products in infants and children, according to a new commentary published in the May 2010 issue of Otolaryngology - Head and Neck Surgery.

3 May 2010

Asthma-like symptoms in infants and toddlers is often RAD

Your child is wheezing. Your child must have asthma, right? Not always, says Julie Koehler, professor and chair of the Department of Pharmacy Practice in Butler University's College of Pharmacy and Health Sciences and clinical pharmacy specialist in family medicine at Clarian Health.

12 Apr 2010

HRV devices reduce respiratory symptoms in children: Study

Houses today are so well sealed that they can trap humidity and pollutants indoors as a result of insufficient ventilation. Recently, a team of Canadian scientists led by Dr. Tom Kovesi, a pediatric respirologist at the Children's Hospital of Eastern Ontario in Ottawa, Canada, performed a randomized double-blind, placebo controlled trial to determine whether use of heat recovery ventilators would increase home ventilation and therefore reduce the risk of lower respiratory tract illness in young children.

7 Apr 2010

Nasal washes may help reduce sinus infection

Washing out your nose with a spray or spout of salt water is safe and might even get you back to work sooner after a cold or acute sinus infection. However, there is not enough evidence to show that it can reduce your symptoms significantly, according to a new research review.

17 Mar 2010

Clinical results of MedImmune's pivotal trial for motavizumab published

MedImmune today announced that clinical results of its pivotal multinational, randomized, double-masked trial for motavizumab have been published in the current issue of the peer-reviewed publication, Pediatrics: Official Journal of the American Academy of Pediatrics.

30 Jan 2010

Medela announces award recipients from November Virtual Human Milk Collection Campaign

Medela announced today the award recipients from its November Virtual Human Milk (breastmilk) Collection Campaign in honor of the March of Dimes' National Prematurity Awareness Month. More than 4,100 participated in the campaign, voting for their preferred Neonatal Intensive Care Unit.

18 Dec 2009

Tarenflurbil drug does not appear to benefit Alzheimer’s patients

Although there were promising results in a phase 2 trial, patients with mild Alzheimer disease who received the drug tarenflurbil as part of a phase 3 trial did not have better outcomes on measures of cognitive decline or loss of activities of daily living compared to patients who received placebo, according to a study in the December 16 issue of JAMA.

15 Dec 2009

The National Fragile X Foundation awards $100,000 grant for study of minocycline in FXS children

The National Fragile X Foundation has awarded a translational research seed grant of $100,000 to Dr. Randi J. Hagerman at the UC Davis M.I.N.D. Institute in California for a study of minocycline in the treatment of children with fragile X syndrome (FXS). Hagerman is an internationally recognized clinician and clinical researcher on FXS, the most common cause of inherited mental impairment.

8 Dec 2009

Study shows herbal medicine is effective for treating acute rhinosinusitis

Rhinosinusitis is an inflammatory process involving one or more of the paranasal sinuses that typically follows a viral upper respiratory tract infection (RTI). The term ‘acute rhinosinusitis’ is used instead of ‘acute sinusitis’ because it is the currently internationally accepted terminology.

4 Dec 2009

Respiratory Tract Infections News and Research

FDA approves cancer drug Afinitor for treatment of rare genetic disorder

Doctors misuse antibiotics to treat patients with respiratory tract infections: Study

Research Roundup: Disabled Medicare Enrollees' challenges; Increasing ER visits; costs/benefits of Part D

Chimpanzee adenoviruses can be used as vaccine vectors: Research

Education, changes in reimbursement practices can reduce inappropriate antibiotic usage: Study

Study suggests reimbursements can address inappropriate antibiotic usage

Phase 3 U.S. registration study of LODOTRA shows improvement in patients with RA

Study examines survival rates of CF patients with MRSA

Vitamin D may help reduce incidence, severity of viral respiratory tract infections: Study

DanActive drink reduces rate of common sicknesses in daycare children, say researchers

Conservative therapies need to be recommended over routine use of OTC cough/cold products in children

Conservative therapies recommended over routine use of OTC cough/cold products in children

Asthma-like symptoms in infants and toddlers is often RAD

HRV devices reduce respiratory symptoms in children: Study

Nasal washes may help reduce sinus infection

Clinical results of MedImmune's pivotal trial for motavizumab published

Medela announces award recipients from November Virtual Human Milk Collection Campaign

Tarenflurbil drug does not appear to benefit Alzheimer’s patients

The National Fragile X Foundation awards $100,000 grant for study of minocycline in FXS children

Study shows herbal medicine is effective for treating acute rhinosinusitis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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