Rhinosinusitis is an inflammation of the paranasal sinuses and the nasal cavity lasting no longer than 4 weeks. It can range from acute viral rhinitis (the common cold) to acute bacterial rhinosinusitis. Fewer than 5 in 1,000 colds are followed by bacterial rhinosinusitis.
New research suggests that Pennsylvania residents with the highest exposure to active natural gas wells operated by the hydraulic fracturing ("fracking") industry are nearly twice as likely to suffer from a combination of migraine headaches, chronic nasal and sinus symptoms and severe fatigue.
In an effort to identify a simple, reliable way to track the course of nasal polyps in chronic sinus disease, Johns Hopkins Medicine researchers say they've linked rising levels of immune system white blood cells, called eosinophils, with regrowth of polyps removed by surgery.
A dozen awards from the National Institutes of Health will support research that incorporates DNA sequence information into electronic medical records. The goal of research conducted by the Electronic Medical Records and Genomics (eMERGE) network is to better understand the genomic basis of disease and to tailor medical care to individual patients based on their genomic differences.
Regeneron Pharmaceuticals, Inc. and Sanofi today announced positive results from the interim analysis of a dose-ranging Phase 2b study of dupilumab in adult patients with uncontrolled moderate-to-severe asthma. Dupilumab is an investigational therapy blocking IL-4 and IL-13, two cytokines required for the Th2 immune response.
People with diabetes mellitus have a significantly increased risk of developing head and neck cancer compared with those without the condition, show results of a large study conducted in Taiwan.
New results from a randomized trial published in the American Journal of Rhinology and Allergy demonstrate the benefits of in-office balloon dilation for sufferers of chronic sinusitis.
The Northwestern Medicine- Sinus and Allergy Center has received a grant for more than $8.4 million from the National Institutes of Health's (NIH) National Institute of Allergy and Infectious Diseases (NIAID) to help advance the understanding of chronic rhinosinusitis (CRS) and the development of new methods for its treatment over the next five years.
The body uses mucus as a protective barrier to defend against pathogens, toxins, and allergens in the upper respiratory tract that can lead to such conditions as chronic sinusitis.
Research from the USA shows that confirmed nasopharyngeal colonization with Streptococcus pneumoniae independently predicts a rapid response to antimicrobial therapy in children with acute sinusitis.
Acclarent, Inc. announced today the U.S. availability of the Relieva Spin Balloon Sinuplasty System with the M-110C Sinus Guide Catheter Tip designed to access small and tight sinus anatomy in children and adults. This innovation represents a new addition to Acclarent's Balloon Sinuplasty portfolio, which physicians use to treat children who suffer from chronic maxillary sinusitis.
Saint Louis University researchers have analyzed the microbiomes of people with chronic rhinosinusitis and healthy volunteers and found evidence that some chronic sinus issues may be the result of inflammation triggered by an immune response to otherwise harmless microorganisms in the sinus membranes.
Research shows that pediatric recurrent community-acquired pneumonia in different lung areas is most commonly associated with mild conditions like rhinosinusitis and asthma, and not severe underlying disease.
Antibiotics for acute rhinosinusitis are prescribed frequently- especially for younger adult patients and in primary care settings-despite recent consensus guidelines that discourage antibiotic use in mild cases, according to a study in the May 2013 issue of Otolaryngology-Head and Neck Surgery.
Amoxicillin is a broad spectrum penicillin, and in the UK is one of the most frequently used antibiotics. It is commonly used either on its own or, where there are particular concerns about resistance, in combination as Co-amoxiclav (as Amoxicillin-clavulanic acid) which extends its anti-bacterial spectrum.
The transmembrane protein Dectin-1 appears to play a role in the pathogenesis of nasal polyposis, providing a potential new target for treating the condition, report Chinese researchers.
People who suffer from chronic rhinosinusitis without nasal polyps have around twice the risk for psoriasis as the general population, a Taiwanese study has found.
The bitter taste receptor TAS2R38 may play a role in innate defense, say researchers, who have found that variations in the TAS2R38 gene may regulate susceptibility to respiratory infection.
The increased expression of a leukotriene receptor and a glucocorticoid receptor may contribute to the development of nasal polyposis, report researchers.
A common bacteria ever-present on the human skin and previously considered harmless, may, in fact, be the culprit behind chronic sinusitis, a painful, recurring swelling of the sinuses that strikes more than one in ten Americans each year, according to a study by scientists at the University of California, San Francisco.
Corticosteroids, frequently prescribed to alleviate acute sinusitis, show no clinical benefit in treating the condition, according to a randomized controlled trial published in CMAJ.