Ribonucleic Acid News and Research

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Influenza hospitalizations at highest level in ten years, predicting a severe U.S. flu season

Influenza infection and hospitalization rates continue to increase at an alarmingly fast and early rate this year.

6 Nov 2022

Exploring BNT162b2 vaccine effectiveness against COVID-19 among pediatric and adolescent population of Qatar

Researchers evaluated Pfizer-BioNTech’s BNT162b2 messenger ribonucleic acid (mRNA) vaccine effectiveness (VE) against SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infections among the pediatric and adolescent population of Qatar.

4 Nov 2022

Efficacy of booster messenger ribonucleic acid COVID-19 vaccinations against SARS-CoV-2 Omicron variant severity

Researchers estimated the effectiveness of monovalent messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) infection severity outcomes among adults.

4 Nov 2022

Study evaluates BA.5-bivalent booster against new Omicron sublineages

In a new study, researchers evaluated the efficacy of four doses of parental messenger ribonucleic acid (mRNA) vaccine and a BA.5-bivalent booster against recently emerged Omicron sublineages. Additionally, they determined whether prior infection improved the effect of a booster vaccination.

4 Nov 2022

Environmental toxicants contribute to obesity and metabolic disease

In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders.

4 Nov 2022

Health of mothers, fetuses, and children are all affected by the maternal environment

A recent editorial published in the journal BMC Medicine examined existing literature for associations between the mother's and offspring's health outcomes and a broad range of maternal characteristics related to pregnancy and postnatal phenotypes and complications.

3 Nov 2022

Circadian disruption induces weight gain through changes in gut microbiota

In a recent study published in the journal Molecular Metabolism, researchers investigated the impact of environmental and genetic disruptions of the circadian rhythms on the peripheral circadian clock synchronization and microbiome oscillations in the gastrointestinal tract.

3 Nov 2022

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Researchers generated and characterized two monoclonal antibodies (NA8 and NE12) that target the receptor binding domain of the SARS-CoV-2 spike protein, and exhibit neutralizing activity against major SARS-CoV-2 variants of concern.

3 Nov 2022

Study explores the potential use of anti-thymic stromal lymphopoietin monoclonal antibody as an adjuvant in allergic immunotherapy

A new study investigated the impact of a monoclonal anti-thymic stromal lymphopoietin (TSLP) antibody on subcutaneous allergen immunotherapy (SCIT) efficacy among patients with allergic rhinitis.

3 Nov 2022

SARS-CoV-2 infections may induce neuroinflammation

Researchers assessed the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on neuroinflammation.

3 Nov 2022

A review of vaccines against the respiratory syncytial virus

This study reviewed the epidemiology, molecular characteristics, populations affected by the virus, and vaccines against RSV.

3 Nov 2022

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

In a recent study posted to the medRxiv* preprint server, researchers in the United States investigated the source of an enigmatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)-like spike (S) protein strain detected in wastewater but not in clinical samples.

2 Nov 2022

Vimentin is an important co-receptor for SARS-CoV-2 infection

Vimentin functions as a co-receptor for the entry of SARS-CoV-2 into host cells to facilitate infection.

2 Nov 2022

Bivalent mRNA booster broadens humoral immunity against SARS-CoV-2 Omicron subvariants

Researchers at Emory University, Stanford University, and the National Institute of Allergy and Infectious Diseases evaluated whether bivalent coronavirus disease 2019 (COVID-19) boosters conferred protection against new Omicron subvariants.

2 Nov 2022

A portable air sampler to quantify and capture SARS-CoV-2 aerosols in laboratories

Researchers in the United Kingdom evaluated a battery-operated portable air sampler that could recover severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aerosolized in a laboratory using a plaque assay.

2 Nov 2022

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

New research describes a novel route of prevention, using messenger ribonucleic acid (mRNA) molecules that encode protective antibodies within the recipient.

2 Nov 2022

Did active monitoring detect potentially elevated risk of health outcomes following BNT162b2 COVID-19 vaccination in the US pediatric population aged 5-17 years?

Researchers used a nearly real-time monitoring framework for early detection of potential safety signals following the administration of the BNT162b2 vaccine in over three million United States children aged five to 17 years.

2 Nov 2022

How does imprinted SARS-CoV-2 humoral immunity drive convergent Omicron evolution?

Researchers examined how imprinted SARS-CoV-2 humoral immunity drives convergent evolution in continuously emerging Omicron subvariants.

2 Nov 2022

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

New research discussed the structure and life cycle of respiratory syncytial virus (RSV), the current research on the treatment and prevention of RSV infections, and the advancements in RSV mRNA vaccine technology after the surge in vaccine research during the COVID-19 pandemic.

1 Nov 2022

Exploring viral loads of SARS-CoV-2 Omicron BA.5 and BA.2 sublineages

In a new study, researchers compared the viral loads of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.5 and BA.2 sublineages.

1 Nov 2022

Ribonucleic Acid News and Research

Influenza hospitalizations at highest level in ten years, predicting a severe U.S. flu season

Exploring BNT162b2 vaccine effectiveness against COVID-19 among pediatric and adolescent population of Qatar

Efficacy of booster messenger ribonucleic acid COVID-19 vaccinations against SARS-CoV-2 Omicron variant severity

Study evaluates BA.5-bivalent booster against new Omicron sublineages

Environmental toxicants contribute to obesity and metabolic disease

Health of mothers, fetuses, and children are all affected by the maternal environment

Circadian disruption induces weight gain through changes in gut microbiota

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Study explores the potential use of anti-thymic stromal lymphopoietin monoclonal antibody as an adjuvant in allergic immunotherapy

SARS-CoV-2 infections may induce neuroinflammation

A review of vaccines against the respiratory syncytial virus

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

Vimentin is an important co-receptor for SARS-CoV-2 infection

Bivalent mRNA booster broadens humoral immunity against SARS-CoV-2 Omicron subvariants

A portable air sampler to quantify and capture SARS-CoV-2 aerosols in laboratories

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

Did active monitoring detect potentially elevated risk of health outcomes following BNT162b2 COVID-19 vaccination in the US pediatric population aged 5-17 years?

How does imprinted SARS-CoV-2 humoral immunity drive convergent Omicron evolution?

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

Exploring viral loads of SARS-CoV-2 Omicron BA.5 and BA.2 sublineages

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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