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COVID‐19 pathology across different tissues

Researchers investigated COVID-19 pathophysiology in multiple tissues, including the lungs, kidneys, heart, and brain, for a deeper understanding of its acute and long‐term symptoms.

7 Oct 2022

Exploring the biomarker profiles in severe COVID-19

In new research, researchers estimated the D-dimer levels and characterized lymphocyte subsets and cytokine profiles in severe coronavirus disease 2019 (COVID-19) patients.

7 Oct 2022

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

Researchers explored SARS-CoV-2-targeted immune responses among COVAC1 participants who received a novel saRNA vaccine followed by the mRNA BNT162b2 vaccine BNT162b2 vaccine, with or without prior COVID-19 history.

7 Oct 2022

The involvement of minor intron-containing gene-encoded proteins in viral infections

Researchers explored the role of the minor intron-containing gene (MIG)-encoded proteins (MIG-Ps) depending on minor spliceosome-MiG excision to be expressed in infections by pathogenic viruses.

6 Oct 2022

Researchers create a clinical scoring system to predict viable viral shedding after COVID-19 infection

A recent study published in the Journal of Clinical Virology developed an individualized scoring system to predict the shedding of viable SARS-CoV-2 from COVID-19 positive patients, which would help to determine personalized isolation strategies.

6 Oct 2022

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

Researchers evaluated the efficacy of dNS1-RBD, a novel intranasal COVID-19 vaccine.

6 Oct 2022

$The immune responses and safety of fractional third-doses of heterologous COVID-19 vaccines after CoronaVac primary series$

The immune responses and safety of fractional third-doses of heterologous COVID-19 vaccines after CoronaVac primary series

Researchers evaluated the vaccine effectiveness of half-doses of AZD1222 or BNT162b2 COVID-19 vaccines as a booster dose following primary series vaccination with CoronaVac.

6 Oct 2022

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

In a new study, researchers developed a three-dimensional (3D) in vitro tissue model to assess the effects of SARS-CoV-2 on the vascular endothelial cells.

5 Oct 2022

Key biophysical attributes of a self-amplifying viral RNA vaccine developed for SARS-CoV-2

Researchers used various analytical characterization techniques to determine the biophysical attributes of the Imperial College London self-amplifying viral RNA vaccine (IMP-1) developed for SARS-CoV-2.

5 Oct 2022

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

Researchers demonstrated that tumor cells evade immunotherapy by generating unique transient cell-in-cell structures, resistant to chemotherapy and destruction by T cells.

5 Oct 2022

Antibody escape mutations of SARS-CoV-2 BA.2.75

A new study discusses how immune escape mutations allow a recent SARS-CoV-2 variant to evade neutralizing antibodies and cause breakthrough infections.

4 Oct 2022

What is the COVID-19 mRNA-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variants?

Researchers evaluated the messenger ribonucleic acid (mRNA)-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variant of concern infections and hospitalizations.

4 Oct 2022

Study attributes increased transmissibility of Monkeypox Clade IIb to genomic accordions

In a new study, researchers performed a genomic study of confirmed Monkeypox virus (MPXV) cases diagnosed in Spain between 18 May and 14 July 2022.

4 Oct 2022

Can you shed infectious SARS-CoV-2 virions even if COVID vaccinated?

Researchers in the United States published a study in the journal PLOS Pathogens that examined the shedding of infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virions despite vaccination against it.

4 Oct 2022

Nursing home study shows 4th COVID mRNA dose provides extra protection against severe Omicron outcomes

In a recent study posted to the medRxiv* preprint server, researchers in Canada assessed the effectiveness of protection elicited by the fourth dose of the coronavirus disease 2019 (COVID-19) mRNA vaccine.

4 Oct 2022

Spike-specific memory B cells develop resilience to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers explored the cross-reactivity, avidity, and kinetics of memory B-cells and serum antibodies in vaccinated and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals.

4 Oct 2022

Ribonucleic Acid News and Research

COVID‐19 pathology across different tissues

Exploring the biomarker profiles in severe COVID-19

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

The involvement of minor intron-containing gene-encoded proteins in viral infections

Researchers create a clinical scoring system to predict viable viral shedding after COVID-19 infection

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

The immune responses and safety of fractional third-doses of heterologous COVID-19 vaccines after CoronaVac primary series

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

Key biophysical attributes of a self-amplifying viral RNA vaccine developed for SARS-CoV-2

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

Antibody escape mutations of SARS-CoV-2 BA.2.75

What is the COVID-19 mRNA-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variants?

Study attributes increased transmissibility of Monkeypox Clade IIb to genomic accordions

Can you shed infectious SARS-CoV-2 virions even if COVID vaccinated?

Nursing home study shows 4th COVID mRNA dose provides extra protection against severe Omicron outcomes

Spike-specific memory B cells develop resilience to SARS-CoV-2

Is it safe to breastfeed after the COVID-19 mRNA vaccination?

The duration of the infectious stage of individuals infected with the SARS-CoV-2 Omicron variant

Novel linear DNA SARS-CoV-2 vaccine using electroporation-aided vaccine delivery reveals lower viral shedding in ferrets

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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