Ribonucleic Acid News and Research

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Study investigates messenger ribonucleic acid-based SARS-CoV-2 vaccine efficacy against SARS-CoV-2 Omicron in Denmark

A new study assessed the efficacy of two SARS-CoV-2 vaccines against Omicron infections and disease-related hospitalization in the Denmark population.

1 Apr 2022

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

1 Apr 2022

TMPRSS2 inhibitor found to be a novel and effective therapeutic option against pan-variant SARS-CoV-2 infections

Researchers assessed the efficacy of TMPRSS2 against SARS-CoV-2 variants of concern Alpha, Beta, Gamma, and Delta, in mice and human lung cells.

1 Apr 2022

Therapeutic antibodies against filoviruses including Ebola and Marburg

Researchers discuss the development and structural characterization of therapeutic monoclonal antibodies targeting the surface glycoprotein of filoviruses.

31 Mar 2022

The longest duration of SARS-CoV-2 positivity after initial diagnosis

An immunocompetent individual with prolonged SARS-CoV-2 shedding 221 days after their initial COVID-19 diagnosis.

31 Mar 2022

Scientists explore impact of SARS-CoV-2 natural immunity on vaccine-induced immunity

A new study investigated the impact of pre-existing SARS-CoV-2 infection-induced immunity on vaccine-induced immunity.

31 Mar 2022

Risk of breakthrough infections by SARS-CoV-2 Omicron and Delta variants in fully vaccinated adults

In a new study, researchers determined the risk of breakthrough infections by SARS-CoV-2 Omicron and Delta variants in fully vaccinated individuals.

31 Mar 2022

Study estimates the comparative abundance of SARS-CoV-2 variants via wastewater monitoring

A recent study estimated the comparative abundance of SARS-CoV-2 variants via wastewater monitoring.

31 Mar 2022

Mosaic-8 RBD-nanoparticles show promise as a vaccine candidate for SARS-CoV-2 and potential sarbecoviruses spillovers

Researchers designed nanoparticles representing RBDs of the S protein of animal sarbecoviruses and SARS-CoV-2 to evaluate their potential as a pan-sarbecovirus vaccine candidate.

31 Mar 2022

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Researchers evaluated the protection conferred by booster doses of the preclinical version of the Moderna mRNA-1273 vaccine and a SARS-CoV-2 Omicron variant-matched vaccine against Omicron infections in mice.

31 Mar 2022

SARS-CoV-2 and pandemic chilblains

Researchers evaluate the pathophysiological relationship between COVID-19 and pandemic-associated chilblain lesions.

30 Mar 2022

A summary of SARS-CoV-2 RNA-protein interactome studies

A new study summarized the importance of SARS-CoV-2 ribonucleic acid protein interactomes in the study of RNA viruses.

30 Mar 2022

Minimal system for SARS-CoV-2 based virus-like particle production to study viral assembly and entry

Researchers proposed an optimal system to generate SARS-CoV-2 virus-like particles for examining viral assembly and entry into target host cells.

30 Mar 2022

Antiviral functions of interferon regulatory factors during human coronavirus infection

Researchers assessed the roles of the interferon regulatory factors: IRF1, IRF3, and IRF7 in infections by human coronaviruses.

30 Mar 2022

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

30 Mar 2022

Study describes the identification of a SARS-CoV-2 variant that escapes detection by antigen tests

Researchers raised concerns that some SARS-CoV-2 variants can escape detection by antigen tests.

30 Mar 2022

Engineering rotavirus-based vaccine vectors expressing SARS-CoV-2 spike epitopes

Researchers proposed rotavirus-based vaccine vectors with the potential for developing polyvalent vaccines targeting multiple enteric viruses, including SARS-CoV-2.

30 Mar 2022

SARS-CoV-2 nucleocapsid protein linked to COVID-19 severity

The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes respiratory coronavirus disease 2019 (COVID-19) triggered an unprecedented public health emergency. Human mobility patterns were fundamental to the spread of SARS-CoV-2 globally. The situation is particularly acute in a country like Saudi Arabia, which has seen more than 750,000 cases and over 9,000 deaths as of March 30th, 2022.

29 Mar 2022

Investigating SARS-CoV-2 detection using Raman microscopy

Researchers investigated the specific intracellular signature of SARS-CoV-2 infection using Raman microscopy.

29 Mar 2022

Evaluating serological responses to repeated COVID-19 vaccination in kidney transplant recipients

Researchers analyzed whether repeated vaccinations against COVID-19 increase serological response in non-responding kidney transplant recipients.

29 Mar 2022

Ribonucleic Acid News and Research

Study investigates messenger ribonucleic acid-based SARS-CoV-2 vaccine efficacy against SARS-CoV-2 Omicron in Denmark

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

TMPRSS2 inhibitor found to be a novel and effective therapeutic option against pan-variant SARS-CoV-2 infections

Therapeutic antibodies against filoviruses including Ebola and Marburg

The longest duration of SARS-CoV-2 positivity after initial diagnosis

Scientists explore impact of SARS-CoV-2 natural immunity on vaccine-induced immunity

Risk of breakthrough infections by SARS-CoV-2 Omicron and Delta variants in fully vaccinated adults

Study estimates the comparative abundance of SARS-CoV-2 variants via wastewater monitoring

Mosaic-8 RBD-nanoparticles show promise as a vaccine candidate for SARS-CoV-2 and potential sarbecoviruses spillovers

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

SARS-CoV-2 and pandemic chilblains

A summary of SARS-CoV-2 RNA-protein interactome studies

Minimal system for SARS-CoV-2 based virus-like particle production to study viral assembly and entry

Antiviral functions of interferon regulatory factors during human coronavirus infection

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Study describes the identification of a SARS-CoV-2 variant that escapes detection by antigen tests

Engineering rotavirus-based vaccine vectors expressing SARS-CoV-2 spike epitopes

SARS-CoV-2 nucleocapsid protein linked to COVID-19 severity

Investigating SARS-CoV-2 detection using Raman microscopy

Evaluating serological responses to repeated COVID-19 vaccination in kidney transplant recipients

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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