Ribonucleic Acid News and Research

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SARS-CoV-2 and pepper mild mottle virus RNA highly persistent in wastewater solids

A new study from the United States (US) investigates the persistence (lifetime) of viral ribonucleic acid (RNA) under different ambient conditions within wastewater infrastructure to understand how it impacts RNA measurements and the related wastewater epidemiology.

11 Jan 2022

Third dose of mRNA COVID vaccine induces strong immunity in older adults

A new study describes the beneficial effects of a third dose of the COVID-19 mRNA vaccine in strengthening immunity among older adults.

11 Jan 2022

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

A new preprint describes a single-step molecular diagnostic test for the presence of SARS-CoV-2 infection caused by the Omicron variant that is behind the unprecedented rise in cases over the last few weeks.

11 Jan 2022

Study finds heterologous vaccine booster evokes robust immunity to SARS-CoV-2 Omicron variant

The current study examines the role of heterologous vaccination, an area that lacks much clarity.

11 Jan 2022

SARS-CoV-2 activates microglia in the brain

Researchers demonstrate that SARS-CoV-2 can infect the human microglia.

10 Jan 2022

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Researchers examine the role of human sirtuin 5 (SIRT5) in SARS-CoV-2 infection.

10 Jan 2022

Neutralization of SARS-CoV-2 variants by three-dose mRNA vaccinated kidney transplant recipient sera

In a new study, researchers determined three-dose messenger ribonucleic acid (mRNA) vaccinated kidney transplant recipients’ (KTRs) neutralizing responses against SARS-COV-2 variants, breakthrough coronavirus disease 2019 infection rate, and transplant rejection rate.

10 Jan 2022

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

A recent study shows how a novel and integrated lab-on-a-chip platform can represent a rapid, affordable, and exact molecular diagnostic tool for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available for free on the medRxiv* preprint server while it undergoes peer review.

9 Jan 2022

Bolstering current therapeutic antibody treatments to help fight Omicron infections

Researchers test the neutralizing action of a panel of eight therapeutic monoclonal antibodies against the SARS-CoV-2 Omicron (B.1.1.529) variant.

9 Jan 2022

Lab engineered human A549 lung cell model conducive for investigating SARS-CoV-2 antivirals

Researchers developed a human A549 lung epithelial cell-based model to probe SARS-CoV-2 replication.

9 Jan 2022

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

The current study was based on merged results using the CDD’s surveillance database coupled with the Vaccine Adverse Event Reporting System (VAERS), along with reports from health departments or physicians to the CDC.

7 Jan 2022

Model suggests feasibility of shorter COVID-19 isolation period with minimal risk

Researchers set up a model that included parameters such as the infectiousness of the individual, and lateral flow testing, in order to assess the effectiveness of test-to-release policies as compared to those with fixed-duration isolation mandates

7 Jan 2022

Evaluating the response of lung cancer patients to COVID-19 mRNA vaccination

Researchers examine the efficacy of mRNA COVID-19 vaccination in NSCLC patients.

6 Jan 2022

How effective are COVID-19 vaccines against the Omicron and Delta variants?

Researchers study the effectiveness of COVID-19 vaccines against the SARS-CoV-2 Omicron and Delta variants.

6 Jan 2022

COVID-19 vaccines effective at varying intensities of SARS-CoV-2 exposure

Researchers investigate the effectiveness of COVID-19 vaccines in individuals at high risk due to their proximity with infected individuals.

6 Jan 2022

Small molecule identified as a SARS-CoV-2 inhibitor

A new study published in iScience reports the results of a screening strategy to identify small molecules that target viral entry to block infection with this virus.

6 Jan 2022

Host kinase identified as an inhibition target for SARS-CoV-2

In this experiment, the chemical probe SGC-CK2-1 inhibited virus replication at nanomolar concentration, showing a highly selective effect on the kinase.

6 Jan 2022

COVID boosters hinder SARS-CoV-2 Omicron

A new preprint research paper reports on the state of current knowledge as to the immune evasion capability of this variant, linking it to the type of vaccine used and the vaccination protocol.

6 Jan 2022

SARS-CoV-2 appears to persist in organs throughout the body for months

The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leads to asymptomatic or mild symptoms in most cases. However, in a significant minority, it causes moderate or severe disease, with lung damage and sometimes multi-organ dysfunction, the origin of which is currently a matter of intense debate.

6 Jan 2022

A new model for predicting COVID-19 severity at diagnosis

Researchers estimate the probabilities of hospitalization and mortality from COVID-19 according to individual risk factors and number of vaccine doses.

5 Jan 2022

Ribonucleic Acid News and Research

SARS-CoV-2 and pepper mild mottle virus RNA highly persistent in wastewater solids

Third dose of mRNA COVID vaccine induces strong immunity in older adults

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

Study finds heterologous vaccine booster evokes robust immunity to SARS-CoV-2 Omicron variant

SARS-CoV-2 activates microglia in the brain

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Neutralization of SARS-CoV-2 variants by three-dose mRNA vaccinated kidney transplant recipient sera

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

Bolstering current therapeutic antibody treatments to help fight Omicron infections

Lab engineered human A549 lung cell model conducive for investigating SARS-CoV-2 antivirals

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

Model suggests feasibility of shorter COVID-19 isolation period with minimal risk

Evaluating the response of lung cancer patients to COVID-19 mRNA vaccination

How effective are COVID-19 vaccines against the Omicron and Delta variants?

COVID-19 vaccines effective at varying intensities of SARS-CoV-2 exposure

Small molecule identified as a SARS-CoV-2 inhibitor

Host kinase identified as an inhibition target for SARS-CoV-2

COVID boosters hinder SARS-CoV-2 Omicron

SARS-CoV-2 appears to persist in organs throughout the body for months

A new model for predicting COVID-19 severity at diagnosis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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