Ribosome News and Research

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Exploring the roles of noise in the eukaryotic cell cycle

A single cell - whether a yeast cell or one of your cells - is exquisitely sensitive to its surroundings.

24 Feb 2009

Molecular machine turns packaged messenger RNA into a linear transcript

For RNA, the gateway to a productive life outside the nucleus is the nuclear pore complex, an amalgamation of 30 kinds of proteins that regulates all traffic passing through the nuclear membrane.

11 Feb 2009

New understanding of how leukemia develops

In a collaborative study published Feb. 9, 2009, in the Proceedings of the National Academy of Sciences (PNAS), scientists performed a genome-wide expression analysis comparing highly enriched normal blood stem cells and leukemic stem cells, and identified several new pathways that have a key role in cancer development.

9 Feb 2009

Bacteria are models of efficiency

The bacterium Escherichia coli, one of the best-studied single-celled organisms around, is a master of industrial efficiency.

5 Feb 2009

Breakthrough in understanding the phenomenon of nucleolar dominance

Since the machinery involved in nucleolar dominance is some of the same machinery that can go haywire in diseases such as cancer, Pikaard and his collaborators' research may have important implications for applied medical research.

5 Dec 2008

Mechanisms of cardiovascular disease and cancer give clues to new therapies

Cardiovascular conditions leading to heart attacks and strokes are treated quite separately from common cancers of the prostate, breast or lung, but now turn out to involve some of the same critical mechanisms at the molecular level.

21 Nov 2008

Scientists discover how certain antibiotics kill bacteria

A series of genetic clues led a team of Boston University biomedical engineers to uncover exactly how certain antibiotics kill bacteria.

17 Nov 2008

Breakthrough in cellular analysis

Like skilled assassins, many diseases seem to know exactly what types of cells to attack.

16 Nov 2008

Breakthrough in cell-type analysis offers new ways to study development and disease

Like skilled assassins, many diseases seem to know exactly what types of cells to attack. While decimating one cadre of cells, diseases will inexplicably spare a seemingly identical group of neighbors. What makes cells vulnerable or not depends largely on the kinds and amounts of proteins they produce - their 'translational profile,' in the lingo of molecular biology. For this reason, scientists have struggled to parse the subtle molecular differences among the hundreds of specialized cell types that are tangled together in tissues like the brain.

13 Nov 2008

Novel tool helps study the biochemical basis of Alzheimer's

A new study being published in this Friday's online edition of Cell will help answer the question, what causes Parkinson's disease?

12 Nov 2008

Evolution in the ribosome

A new study of the ribosome, the cell's protein-building machinery, sheds light on the oldest branches of the evolutionary tree of life and suggests that differences in ribosomal structure between the three main branches of that tree are "molecular fossils" of the early evolution of protein synthesis.

18 Aug 2008

New technology revolutionizing drug discovery

The National Science Foundation has awarded Weill Cornell Medical College researcher Dr. Scott Blanchard its prestigious Career Award, recognizing his groundbreaking work in cell biology -- work that is poised to revolutionize research for the next generation of young scientists.

15 Jul 2008

Advances in RNA research

RNA, the transporter of genetic information within the cell, has emerged from the shadow of DNA to become one of the hottest research areas of molecular biology, with implications for many diseases as well as understanding of evolution. But the field is complex, requiring access to the latest equipment and techniques of imaging, gene expression analysis and bioinformatics, as well as cross-pollination between multiple scientific disciplines.

10 Jul 2008

European researchers take lid off the genome

European researchers have made significant progress unravelling how genes are governed and why this sometimes goes wrong in disease.

15 Jun 2008

New understanding of how some bacteria survive antibiotic treatment

Researchers at the University of Illinois at Chicago have discovered how some bacteria can survive antibiotic treatment by turning on resistance mechanisms when exposed to the drugs.

30 Apr 2008

TOR signaling and dietary restriction

University of Washington scientists have uncovered details about the mechanisms through which dietary restriction slows the aging process.

17 Apr 2008

Discovery of critical detail of cellular defense against genetic mistakes

Researchers are closing in on a completed diagram of how human cells protect themselves against constant genetic mistakes that contribute to most diseases, according to a study to be published in the April 18 edition of the journal Cell.

17 Apr 2008

Common molecule tRNA involved in building protein can trigger cancer

Cancer Research UK scientists have discovered that a common molecule previously known to play a fundamental role in building protein, can also trigger cancer.

7 Apr 2008

Protein that stimulates blood vessel growth worsens ovarian cancer

A protein that stimulates blood vessel growth worsens ovarian cancer, but its production can be stifled by a tiny bit of RNA wrapped in a fatty nanoparticle, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Journal of the National Cancer Institute.

27 Feb 2008