S. cerevisiae News and Research

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Scientists shed light on how DNA is unwound so that its code can be read

Researchers at The Scripps Research Institute have figured out how a macromolecular machine is able to unwind the long and twisted tangles of DNA within a cell's nucleus so that genetic information can be "read" and used to direct the synthesis of proteins, which have many specific functions in the body.

24 Nov 2008

Prion switching in response to environmental stress

If you have had a hard day at work, you may change your eating habits, perhaps favoring comfort food, but you don't suddenly develop the ability to eat the plate and cutlery.

24 Nov 2008

FDA strengthens safety of Sucraid (sacrosidase) oral solution

The U.S. Food and Drug Administration today issued an expedited approval of a supplemental application that allows for changes in the manufacturing of Sucraid (sacrosidase) Oral Solution.

20 Nov 2008

Biologists identify genes that prevent changes in physical traits due to environmental changes

New York University biologists have identified genes that prevent physical traits from being affected by environmental changes.

4 Nov 2008

Yeast-based vaccine induces immune responses and reduces tumor size in mice

Scientists have found that vaccination with a heat-killed, non-toxic yeast that is genetically engineered to manufacture a common tumor protein can induce specific and repeated anti-tumor immune responses in mice.

1 Jul 2008

Scientists identify key roadblock to gene expression

A team of scientists has provided, for the first time, a detailed map of how the building blocks of chromosomes, the cellular structures that contain genes, are organized in the fruit fly Drosophila melanogaster. The work identifies a critical stop sign for transcription, the first step in gene expression, and has implications for understanding how the AIDS virus regulates its genes. The findings will be published in the 15 May 2008 issue of the journal Nature

8 May 2008

New discovery on how gene-regulatory networks govern metabolism

Metabolism is a central feature of life - a myriad of biochemical processes that, together, enable organisms to nourish and sustain themselves.

26 Feb 2008

The cell size problem

For more than 100 years, scientists have tried to figure out the cell size problem: How does a cell know when it is big enough to divide?

25 Sep 2007

Researchers pinpoint when a cell is ready to reproduce

For more than 100 years, scientists have tried to figure out the cell size problem: How does a cell know when it is big enough to divide, In research conducted in budding yeast ( Saccharomyces cerevisiae ), scientists at Rockefeller University have now identified the cellular event that marks the moment when a cell knows it is big enough to commit to cell division and spawn genetic replicas of itself.

24 Sep 2007

Penn State scientists reveal structure of gateways to gene control

Scientists at Penn State University will reveal in the 29 March 2007 issue of the journal Nature the first complete high-resolution map of important structures that control how genes are packaged and regulated throughout an entire genome.

31 Mar 2007

Latest sequencing targets for NHGRI

The National Human Genome Research Institute (NHGRI) has announced several new sequencing targets including the Northern white-cheeked gibbon (Nomascus leucogenys).

19 Jul 2006

Important new global mechanism for gene repression

Most of the time in most cells of the body, the great majority of genes are silenced, locked away within the compacted but orderly material that makes up chromosomes.

18 Apr 2006

Cheap way to produce expensive malaria drug well on the way

U.S. researchers say a cheap way to produce an expensive but effective malaria drug is well on the way.

13 Apr 2006

First genome-wide screen for protein complexes is completed

Researchers in Germany have finished the first complete analysis of the "molecular machines" in one of biology's most important model organisms: S. cerevisiae (baker's yeast). The study from the biotechnology company Cellzome, in collaboration with the European Molecular Biology Laboratory (EMBL), appears in this week's online edition of Nature.

23 Jan 2006

Artificial cobweb proteins for medicine

A unique material based on cobweb proteins is being created by Russian researchers of the State Research Center of Russian Federation GosNIIgentics, Scientific Research Center “Coal-Chemical Fiber”, State Research Center of Applied Microbiology in cooperation with their colleagues from Michigan University with support form the International Science and Technology Center (ISTC) (project 1033.2).

30 May 2005

Fibril shape is the basis of prion strains and cross-species prion infection

New research on prions, the infectious proteins behind "mad cow" disease and Creutzfeld-Jakob disease in humans, suggests that the ability of prions in one species to infect other species depends on the shape of the toxic threadlike fibers produced by the prion. Two studies on the topic appear in the 8 April issue of the journal Cell.

7 Apr 2005