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The effect of amino acid substitutions in variants of concern on RBD:ACE2 bond kinetics

Researchers explored the effects of mutations in the SARS-CoV-2 variants of concern on viral transmission.

12 Jan 2023

Annual or biannual boosters greatly reduce the long-term risk of infection from endemic COVID-19

While COVID-19 boosters have been found to protect against infection, hospitalization, and severe illness, the waning of their protection has led to uncertainty about when it is most appropriate to get an additional booster shot.

11 Jan 2023

Bivalent boosters tested against all SARS-CoV-2 Omicron lineages

In a recent study posted to the bioRxiv* preprint server, researchers in the United States assessed the impact of the bivalent messenger ribonucleic acid (mRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine on the antibody-mediated neutralization of the SARS-CoV-2 Omicron lineages.

11 Jan 2023

Rethinking next generation of improved vaccines for mucosa-replicating viruses

Vaccines that provide long-lasting protection against influenza, coronaviruses and respiratory syncytial virus (RSV) have proved exceptionally difficult to develop.

11 Jan 2023

COVID-19 outcomes in Rituximab treated patients

A new report throws light on SARS-CoV-2 breakthrough infections in patients with certain joint diseases or musculoskeletal conditions who are on rituximab and compares the severity of COVID-19 outcomes in these patients whilst identifying potential risk factors for severe outcomes.

11 Jan 2023

Researchers study congenital abnormalities after COVID-19 infection and vaccination

Researchers compared the significant congenital abnormalities observed after coronavirus disease 2019 (COVID-19) infection and vaccination.

11 Jan 2023

2022: a year in MIS-C research

In a recent review published in Nature Reviews Rheumatology, researchers reviewed existing data on the multisystem inflammatory syndrome in children (or MIS-C).

11 Jan 2023

Real-world effectiveness of the bivalent vaccine for preventing COVID-19 hospitalizations in non-hospitalized subjects

Researchers investigated the efficacy of a booster dose of the bivalent mRNA COVID-19 vaccine in preventing severe outcomes during SARS-CoV-2 infections.

11 Jan 2023

Review shows metformin usage to be associated with better COVID-19 outcomes

Researchers reported on the potential association between metformin usage and coronavirus disease 2019 (COVID-19) outcomes.

11 Jan 2023

Study suggests many symptoms are more common after COVID-19 infection, but only a few are commonly associated with a long COVID diagnosis

Researchers compared symptoms in patients with and without prior COVID-19 history and investigated symptoms associated with long COVID diagnosis in the UK.

11 Jan 2023

MALAT1 suppression is a hallmark of tissue and peripheral proliferative T cells in COVID-19

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom investigated lncRNA (long non-coding ribonucleic acids) expression in coronavirus disease 2019 (COVID-19) T lymphocyte transcriptomes.

10 Jan 2023

MIS-C more common and severe than previously thought

In a recent study published in the JAMA Network Open journal, researchers compared the characteristics of multisystem inflammatory syndrome in children (MIS-C) and coronavirus disease 2019 (COVID-19).

10 Jan 2023

Spike protein mutations in Omicron subvariants increase their susceptibility to reductive cleavage of disulfide bonds

Researchers discovered that the spike protein of SARS-CoV-2 is susceptible to cleavage at the disulfide bonds, and the vulnerability to reductive cleavage varies across variants, with the Omicron variant family being highly susceptible to reduction.

10 Jan 2023

Study explores incidence, severity, and long COVID associations of SARS-CoV-2 reinfections

Researchers used electronic health records to characterize the incidence, biomarkers, attributes, and severity of SARS-CoV-2 reinfections and evaluated the association between reinfections and long coronavirus disease (COVID).

10 Jan 2023

Researchers review bacteriophage treatment

Researchers presented an overview of bacteriophage treatment, including mechanisms, types, design and applications of bacteriophage therapy.

10 Jan 2023

Wellcome Sanger Institute launches new initiative to better understand respiratory viruses

A new initiative to better understand respiratory viruses has been launched today (10 January 2023) by the Wellcome Sanger Institute.

10 Jan 2023

Study suggests that long-COVID is associated with physical inactivity

In a recent study published in the Scientific Reports journal, researchers in Brazil assessed the association between post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) and physical inactivity.

9 Jan 2023

Compounds derived from B.C. sea sponge can prevent COVID-19 infection in human cells

UBC researchers have identified three compounds that prevent COVID-19 infection in human cells, derived from natural sources including a B.C. sea sponge.

9 Jan 2023

Researchers study the spatial distribution of SARS-CoV-2 Omicron BA.1 variant in England

Researchers performed a genomic assessment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant’s BA.1 subvariant transmission in England.

9 Jan 2023

NIH awards eight research grants to advance diagnosis of Multisystem Inflammatory Syndrome in Children

The National Institutes of Health has awarded eight research grants to refine new technologies for early diagnosis of severe illnesses resulting from SARS-CoV-2 infection in children.

9 Jan 2023

SARS News and Research

The effect of amino acid substitutions in variants of concern on RBD:ACE2 bond kinetics

Annual or biannual boosters greatly reduce the long-term risk of infection from endemic COVID-19

Bivalent boosters tested against all SARS-CoV-2 Omicron lineages

Rethinking next generation of improved vaccines for mucosa-replicating viruses

COVID-19 outcomes in Rituximab treated patients

Researchers study congenital abnormalities after COVID-19 infection and vaccination

2022: a year in MIS-C research

Real-world effectiveness of the bivalent vaccine for preventing COVID-19 hospitalizations in non-hospitalized subjects

Review shows metformin usage to be associated with better COVID-19 outcomes

Study suggests many symptoms are more common after COVID-19 infection, but only a few are commonly associated with a long COVID diagnosis

MALAT1 suppression is a hallmark of tissue and peripheral proliferative T cells in COVID-19

MIS-C more common and severe than previously thought

Spike protein mutations in Omicron subvariants increase their susceptibility to reductive cleavage of disulfide bonds

Study explores incidence, severity, and long COVID associations of SARS-CoV-2 reinfections

Researchers review bacteriophage treatment

Wellcome Sanger Institute launches new initiative to better understand respiratory viruses

Study suggests that long-COVID is associated with physical inactivity

Compounds derived from B.C. sea sponge can prevent COVID-19 infection in human cells

Researchers study the spatial distribution of SARS-CoV-2 Omicron BA.1 variant in England

NIH awards eight research grants to advance diagnosis of Multisystem Inflammatory Syndrome in Children

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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