SARS CoV 2 News and Research

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Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

Researchers explore the thermodynamic properties of the SARS-CoV-2 Omicron subvariant BA.2.75 to understand its increased transmissibility.

27 Oct 2022

Study examines the severity of the SARS-CoV-2 Omicron BA.2 subvariant

In a recent study that represents the largest to date to examine the severity of the SARS-CoV-2 Omicron BA.2 subvariant (the strain making a re-emergence this fall), a team led by investigators at Massachusetts General Hospital (MGH) determined that the BA.2 subvariant is less severe than the previous Delta variant and less severe to an even greater extent than the original Omicron variant.

27 Oct 2022

Hydrogel bioink can bioprint conduits that mimic the mechanics of native blood vessels

Cardiovascular diseases (CVDs) remain among the leading causes of global morbidity and mortality. In patients with CVD, blood vessels-which transport blood, oxygen, and nutrients-can become constricted or obstructed, leading to numerous complications.

27 Oct 2022

Is vaccine status associated with the severity of Omicron SARS-CoV-2 infection in hospitalized patients?

Researchers assessed the impact of SARS-CoV-2 vaccination on the occurrence and severity of symptoms in SARS-CoV-2 Omicron-infected hospitalized patients.

27 Oct 2022

The effectiveness of BNT162b2 COVID-19 vaccine against infection with SARS-CoV-2 Omicron subvariants BA.4/5

Researchers evaluated the vaccine effectiveness of Pfizer-BioNTech’s BNT162b2 COVID-19 vaccines against SARS-CoV-2 Omicron BA.4/5.

27 Oct 2022

Rare variants of type I IFN immunity genes could underlie life-threatening COVID-19

Researchers assessed whether loss-of-function variants of type I interferon immunity genes are associated with life-threatening COVID-19.

27 Oct 2022

What is the association between regular physical activity and vaccination against COVID-19 among healthcare workers?

Researchers assessed the association between daily physical activity and COVID-19 vaccination among HCWs.

27 Oct 2022

Vaccination- and/or natural infection-induced immune responses against SARS-CoV-2 Omicron subvariants

Researchers comparatively evaluated the neutralization antibody titers for SARS-CoV-2 Omicron VOC subvariants BA.1, BA.2, BA.4/5 among individuals with ancestral B.1 strain infections, vaccinated individuals, or with hybrid immunity from breakthrough infections and vaccinations with Delta or Gamma VOCs.

27 Oct 2022

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

Researchers reported three human monoclonal antibodies generated from COVID-19-recovered individuals during the initial wave of the pandemic in India.

27 Oct 2022

Study finds that ACE-2 is not biochemically required for SARS-CoV2 membrane fusion

A study tested the hypothesis that the ACE-2 receptor of SARS-CoV-2 is not only an attachment factor in viral infection but also plays a role in activating the viral spike protein to facilitate membrane fusion.

27 Oct 2022

Some healthcare workers vaccinated against COVID-19 show unexpectedly low responses to immunizations

A subset of healthcare workers vaccinated against COVID-19 had unexpectedly low responses to the immunizations, according to Cedars-Sinai investigators.

27 Oct 2022

What is the efficacy of RT-PCR assays for detection of SARS-CoV-2 in human semen?

A new study aimed to develop a standardized protocol for SARS-CoV-2 RNA detection in semen fractions used for assisted reproductive technology.

26 Oct 2022

What is the association of self-reported post-vaccination symptoms with anti–SARS-CoV-2 antibody response?

Researchers investigated the association of symptoms after COVID-19 vaccination with antibody responses against SARS-CoV-2.

26 Oct 2022

How important is sterilizing immunity in protection against SARS-CoV-2?

The authors discussed the underlying principles of sterilizing immunity and its importance in protecting individuals against SARS-CoV-2 reinfections during the COVID-19 pandemic.

26 Oct 2022

Omicron BA.4/BA.5 bivalent mRNA vaccine booster elicits similar neutralizing antibody responses to monovalent vaccine

Researchers analyzed the antibody response induced by the new bivalent mRNA SARS-CoV-2 vaccines in individuals who have been fully vaccinated with monovalent vaccines and those who have had breakthrough infection with the SARS-CoV-2 Omicron BA.4/BA.5 variants.

26 Oct 2022

Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

Researchers analyzed the phenotypes of the SARS-CoV-2 variants of concern (VOCs), the molecular responses to infections from these VOCs, and the evolving virus-host interactions using a comparative genomic and proteomic approach.

26 Oct 2022

Study uses compartmental modeling to test the efficiency of sentinel surveillance for developing public COVID-19 mitigation policies

Researchers used a stochastic compartmental model of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission to examine various sentinel surveillance indicators and determine the minimal sampling effort required for a reliable alert indicating a one-step increase in transmission rate.

26 Oct 2022

SARS CoV 2 News and Research

Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

Study examines the severity of the SARS-CoV-2 Omicron BA.2 subvariant

Hydrogel bioink can bioprint conduits that mimic the mechanics of native blood vessels

Is vaccine status associated with the severity of Omicron SARS-CoV-2 infection in hospitalized patients?

The effectiveness of BNT162b2 COVID-19 vaccine against infection with SARS-CoV-2 Omicron subvariants BA.4/5

Rare variants of type I IFN immunity genes could underlie life-threatening COVID-19

What is the association between regular physical activity and vaccination against COVID-19 among healthcare workers?

Vaccination- and/or natural infection-induced immune responses against SARS-CoV-2 Omicron subvariants

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

Study finds that ACE-2 is not biochemically required for SARS-CoV2 membrane fusion

Some healthcare workers vaccinated against COVID-19 show unexpectedly low responses to immunizations

What is the efficacy of RT-PCR assays for detection of SARS-CoV-2 in human semen?

What is the association of self-reported post-vaccination symptoms with anti–SARS-CoV-2 antibody response?

How important is sterilizing immunity in protection against SARS-CoV-2?

Omicron BA.4/BA.5 bivalent mRNA vaccine booster elicits similar neutralizing antibody responses to monovalent vaccine

Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

Study uses compartmental modeling to test the efficiency of sentinel surveillance for developing public COVID-19 mitigation policies

SARS-CoV-2 BQ.1 variant cases may increase in Europe

COVID-19 and the gut

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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