SARS CoV 2 News and Research

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Yale and AI Therapeutics launch clinical trial of potential COVID-19 drug

Yale School of Medicine and the biopharmaceutical firm AI Therapeutics have launched a multi-institutional clinical trial of a drug for treating COVID-19.

27 Jul 2020

Brigham to play two key roles in phase 3 trial of COVID-19 vaccine candidate

A vaccine candidate for preventing COVID-19 is advancing to a 30,000-participant phase 3 trial that begins today, and Brigham and Women's Hospital will play two key roles in the trial's next phase.

27 Jul 2020

Alternative amplification technique could accelerate COVID-19 testing

An alternative amplification technique to detect SARS-CoV-2 RNA could offer a way to rapidly test large numbers of people for COVID-19, although the technique is not as sensitive as quantitative RT-PCR, the current standard method for COVID-19 testing.

27 Jul 2020

AI Therapeutics announces start of Phase II clinical trial of potential COVID-19 treatment

AI Therapeutics announced the start of Phase II clinical trial for the treatment of newly diagnosed COVID-19 patients in collaboration with Yale University.

27 Jul 2020

Clinical trials of hydroxychloroquine in COVID-19 outpatients reported as safe

According to new research, the use of hydroxychloroquine among outpatients in clinical trials, without high-risk factors for cardiac arrhythmia, is safe.

27 Jul 2020

Study reveals manifold applications of cytokine transcriptional response modules in COVID-19

In a recent bioRxiv* study, UK researchers used interleukin modules to investigate the pathology of coronavirus disease (COVID-19).

27 Jul 2020

Study provides new insights into the host cellular response to SARS-CoV-2 infection

The COVID-19 pandemic caused by the new coronavirus has created an unprecedented public health challenge globally. Little was known about how the infecting cells respond to the virus and how the virus hijacks the host cellular machinery.

27 Jul 2020

High ACE2 Expression on pancreatic islet cells during inflammation could explain new-onset diabetes in COVID-19

A new study suggests that the SARS-CoV-2 infection may be linked to the onset of diabetes, via the infection of pancreatic islet beta cells, which produce insulin.

27 Jul 2020

Face masks do not lead to false sense of security, shows study

Existing limited evidence suggests that wearing face coverings to protect against COVID-19 does not lead to a false sense of security and is unlikely to increase the risk of infection through wearers foregoing other behaviours such as good hand hygiene, say researchers from the University of Cambridge and King's College London.

27 Jul 2020

New approach could enable wider adoption of COVID-19 testing for diagnosis in research laboratories

Clinician-scientists at Nanyang Technological University, Singapore's (NTU Singapore) Lee Kong Chian School of Medicine (LKCMedicine) have demonstrated a way to improve the speed, handling time and cost of COVID-19 laboratory tests.

27 Jul 2020

Researchers identify anticoagulation agent that suppresses SARS-CoV-2 replication in vitro

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause acute respiratory distress syndrome, hypercoagulability, hypertension, and multiorgan dysfunction.

27 Jul 2020

Scientists develop COVID-19 test to detect neutralizing antibodies with high sensitivity, specificity

According to a study published in Nature Biotechnology, the sVNT is capable of detecting the functional neutralizing antibodies (NAbs) that can block the binding of the coronavirus spike protein to the angiotensin-converting enzyme 2 (ACE2) host receptor, which mimics the virus-host interaction.

25 Jul 2020

National clinical trial to test potential vaccine against SARS-CoV-2

UC San Diego Health and the Altman Clinical and Translational Research Institute, part of UC San Diego School of Medicine, will be sites for an accelerated national clinical trial to assess the efficacy and immunogenicity of a vaccine intended to protect against SARS-CoV-2, the novel coronavirus that causes COVID-19.

25 Jul 2020

Study identifies mechanisms that underlie olfactory symptoms of COVID-19

A new study of human olfactory cells has revealed that viral invasion of supportive cells in the nasal cavity might be driving the loss of smell seen in some patients with COVID-19.

25 Jul 2020

Olfactory cell types are most vulnerable to COVID-19 infection, shows study

Temporary loss of smell, or anosmia, is the main neurological symptom and one of the earliest and most commonly reported indicators of COVID-19.

25 Jul 2020

Higher levels of TGFBIp are correlated with severity of COVID-19 symptoms

A new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.

25 Jul 2020

Researchers identify TLR7 gene that predisposes elderly patients to severe COVID-19

Current observations suggest that the coronavirus SARS-CoV-2 causes severe symptoms mainly in elderly patients with chronic disease.

25 Jul 2020

MP Biomedicals and A*STAR jointly develop rapid antibody test kit for COVID-19

MP Biomedicals Asia Pacific Pte Ltd, a diagnostic corporation which has been operating for over 30 years focusing on various infectious disease testing development and manufacturing, today announced the successful development of a rapid antibody test kit for COVID-19, in collaboration with the Agency for Science, Technology and Research.

From MP Biomedicals, LLC 25 Jul 2020

Sputum testing detects COVID-19 virus at higher rates than other methods

Early and accurate detection is critical for preventing the spread of COVID-19 and providing appropriate care for patients.

24 Jul 2020

Study finds a sharp decline in heart transplants during the pandemic

The number of heart transplants in the United States declined sharply during the beginning of the pandemic, even in areas of the country with few COVID-19 cases at the time, according to an analysis by researchers at Columbia University Irving Medical Center.

24 Jul 2020

SARS CoV 2 News and Research

Yale and AI Therapeutics launch clinical trial of potential COVID-19 drug

Brigham to play two key roles in phase 3 trial of COVID-19 vaccine candidate

Alternative amplification technique could accelerate COVID-19 testing

AI Therapeutics announces start of Phase II clinical trial of potential COVID-19 treatment

Clinical trials of hydroxychloroquine in COVID-19 outpatients reported as safe

Study reveals manifold applications of cytokine transcriptional response modules in COVID-19

Study provides new insights into the host cellular response to SARS-CoV-2 infection

High ACE2 Expression on pancreatic islet cells during inflammation could explain new-onset diabetes in COVID-19

Face masks do not lead to false sense of security, shows study

New approach could enable wider adoption of COVID-19 testing for diagnosis in research laboratories

Researchers identify anticoagulation agent that suppresses SARS-CoV-2 replication in vitro

Scientists develop COVID-19 test to detect neutralizing antibodies with high sensitivity, specificity

National clinical trial to test potential vaccine against SARS-CoV-2

Study identifies mechanisms that underlie olfactory symptoms of COVID-19

Olfactory cell types are most vulnerable to COVID-19 infection, shows study

Higher levels of TGFBIp are correlated with severity of COVID-19 symptoms

Researchers identify TLR7 gene that predisposes elderly patients to severe COVID-19

MP Biomedicals and A*STAR jointly develop rapid antibody test kit for COVID-19

Sputum testing detects COVID-19 virus at higher rates than other methods

Study finds a sharp decline in heart transplants during the pandemic

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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