Sarcopenia News and Research

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Treatment for muscle wasting improved survival in pre-clinical cancer model

Researchers from the University of Jyväskylä in Finland have found that continued treatment of muscle wasting with a soluble growth factor receptor protein, produced at the University of Helsinki, improved survival in a pre-clinical cancer model without affecting the tumor size.

15 May 2018

New model based on combination of GANs with reinforcement learning for drug discovery

Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for target identification, drug discovery and aging research announces the publication of a new research paper in Molecular Pharmaceutics journal titled "Adversarial Threshold Neural Computer for Molecular De Novo Design".

10 May 2018

Insilico’s CEO to deliver presentation on “Artificial Intelligence for Aging Research”

Insilico Medicine, a Baltimore-based company specializing in the application of next-generation artificial intelligence for drug discovery, biomarker development and aging research, announces the presentation of its CEO, Alex Zhavoronkov, at the Pioneers 18 Conference, May 25, 2018, Vienna, Austria.

28 Apr 2018

LSD1 enzyme regulates skeletal muscle differentiation and metabolic activity

Our bodies convert food into energy for all life activities. These metabolic processes allow the cells that make up our bodies to produce (anabolism) and consume (catabolism) energy molecules from nutrients.

12 Apr 2018

Breast cancer survival linked to muscle mass finds study

Researchers have found that women with breast cancer who have a low muscle mass are less likely to survive stage 2 and 3 cancers. The study titled, “Association of Muscle and Adiposity Measured by Computed Tomography with Survival in Patients with Nonmetastatic Breast Cancer,” appears in the latest issue of the journal JAMA Oncology.

9 Apr 2018

Insilico to present recent advances in AI for aging biomarkers and age management research

Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for drug discovery, biomarker development and aging research, is pleased to announce the presentation of its Director of Drug Discovery, Dr. Ivan Ozerov, at the 24th Clinical Applications for Age Management Medicine Conference, April 27, 2018, organized by Age Management Medicine Group.

6 Apr 2018

New study identifies key cellular mechanisms behind vascular aging in mice

We are as old as our arteries, the adage goes, so could reversing the aging of blood vessels hold the key to restoring youthful vitality? The answer appears to be yes, at least in mice, according to a new study led by investigators at Harvard Medical School.

22 Mar 2018

Muscle wasting of old age and ways to stop it understood in new study

According to latest research, the muscle wasting that is associated with ageing has been attributed to loss of nerves. Researchers from the Manchester Metropolitan University, The University of Manchester, The University of Waterloo in Ontario, and Central Manchester University Hospitals NHW Foundation Trust published their study findings in the latest issue of The Journal of Physiology.

13 Mar 2018

Researchers investigate protective systems that could reverse muscle loss in old age

A new study has helped to shed light on the process underlying muscle loss in old age, a condition that increases people’s risk of frailty and disability.

12 Mar 2018

First drug-candidate compounds discovered using AI licensed for development

Insilico Medicine, Inc., a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for drug discovery, announces that Juvenescence.AI, its joint venture with Juvenescence Limited, has licensed its first compound family for clinical development.

7 Feb 2018

Insilico Medicine develops new deep-learning based hematological human aging clock

Today, Insilico Medicine, Inc., a Baltimore-based company specializing in the application of artificial intelligence for drug discovery, biomarker development and aging research, announced a publication of a research paper titled "Population-specific biomarkers of human aging: a big data study using South Korean, Canadian and Eastern-European patient populations" in The Journal of Gerontology.

11 Jan 2018

Study reveals biology behind why muscle stem cells respond differently to aging or injury

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute describes the biology behind why muscle stem cells respond differently to aging or injury.

15 Dec 2017

Deep-learning technology reveals anti-aging plant extracts

Life Extension, in collaboration with Insilico Medicine, have employed artificial intelligence to develop a novel dietary supplement of plant extracts that can activate the body's own anti-aging path ways.

31 Oct 2017

Small increases in physical exercise can lower chances for major mobility loss in older adults

Adding 48 minutes of moderate exercise per week is associated with improvements in overall physical functioning and decreases in risks of immobility in older adults who are sedentary, finds a new study led by researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University.

11 Sep 2017

Insilico and GSK collaborate to enhance drug discovery process

Insilico Medicine, a Baltimore-based company at the forefront of artificial intelligence (AI) research for drug discovery, biomarker development and aging research announced today that it has formed a collaboration with GSK to explore how Insilico's AI capability can enhance its drug discovery process.

16 Aug 2017

Sarcopenia News and Research

Treatment for muscle wasting improved survival in pre-clinical cancer model

New model based on combination of GANs with reinforcement learning for drug discovery

Insilico’s CEO to deliver presentation on “Artificial Intelligence for Aging Research”

LSD1 enzyme regulates skeletal muscle differentiation and metabolic activity

Breast cancer survival linked to muscle mass finds study

Insilico to present recent advances in AI for aging biomarkers and age management research

New study identifies key cellular mechanisms behind vascular aging in mice

Muscle wasting of old age and ways to stop it understood in new study

Researchers investigate protective systems that could reverse muscle loss in old age

First drug-candidate compounds discovered using AI licensed for development

Insilico Medicine develops new deep-learning based hematological human aging clock

Study reveals biology behind why muscle stem cells respond differently to aging or injury

Deep-learning technology reveals anti-aging plant extracts

Small increases in physical exercise can lower chances for major mobility loss in older adults

Insilico and GSK collaborate to enhance drug discovery process

New partnership uses artificial intelligence methods to develop solutions for preventing early aging

Juvenescence AI to develop first compounds generated by Insilico's deep-learned drug discovery engines

Scientists gain better understanding of genetics behind lean body mass

AI and deep learning can help visualize human bias in complex systems

ActuRx and Insillico Medicine collaborate to prevent, treat age-related illnesses

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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