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Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

Understanding the relationship between SARS-CoV-2 infection and periodontitis

In a recent review published in the journal International Journal of Molecular Sciences, researchers reviewed existing data on the association between periodontitis and coronavirus disease 2019 (COVID-19).

7 Feb 2023

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers evaluated COVID-19 management based on sex differences.

3 Feb 2023

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

A recent study evaluates the presence of SARS-CoV-2 in children’s tonsils during the COVID-19 pandemic.

29 Jan 2023

Altered amino acid metabolism could contribute to diabetes-associated peripheral neuropathy

Approximately half of people with type 1 or type 2 diabetes experience peripheral neuropathy-;weakness, numbness, and pain, primarily in the hands and feet.

25 Jan 2023

Researchers identify a key host-cell player in COVID-19 infections

Researchers at University of California San Diego and UC Riverside have further elucidated the molecular pathway used by the SARS-CoV-2 virus to infect human lung cells, identifying a key host-cell player that may prove a new and enduring therapeutic target for treating COVID-19.

24 Jan 2023

Exploring the infectivity, transmissibility, and immunological resistance characteristics of SARS-CoV-2 Omicron XBB.1.5 strain

Researchers performed an epidemic dynamic analysis to assess the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)’s sub-VOC XBB.1.5 characteristics.

19 Jan 2023

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Researchers explored the relationship between the development of goblet inflammatory cells and the age-related pathophysiology of SARS-CoV-2.

19 Jan 2023

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Researchers explored how mutations in emergent SARS-CoV-2 variants affect viral function, human immunity, and recognition by therapeutic antibodies.

19 Jan 2023

Artemisia argyi plant extracts and phytochemicals shown to inhibit SARS-CoV-2 in new research

Researchers reported that Artemisia argyi extracts and phytochemicals could inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Jan 2023

The loss of epigenetic information accelerates the aging process

A new study in the journal Cell aimed to determine whether epigenetic changes are a cause of mammalian aging.

15 Jan 2023

Study on the ecology of viruses in urban rodents with special emphasis on SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers investigated whether commensal rodent pests such as rats and mice, sourced from sewers and urban settings, are exposed to and are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They also investigated viruses present in commensal rodents.

12 Jan 2023

Comprehensive atlas of protein kinases could help scientists decipher many cellular signaling pathways

One of the most important classes of human enzymes are protein kinases -; signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism.

12 Jan 2023

Certain type of glial cell plays a major role in spatial learning

There are two fundamentally different cell types in the brain, neurons and glial cells. The latter, for example, insulate the "wiring" of nerve cells or guarantee optimal working conditions for them.

10 Jan 2023

Study shows XBB.1.5 exhibits a substantially higher hACE2-binding affinity compared to BQ.1.1 and XBB/XBB.1

Researchers investigated the reasons for the rapid advent of SARS-CoV-2 XBB.1.5, a sublineage of the Omicron recombinant mutant XBB in the USA.

6 Jan 2023

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Announcing a new article publication for Zoonoses journal. This study was aimed at screening differentially expressed genes (DEGs) and exploring the potential immune mechanism induced by the Bacillus Calmette-Guerin (BCG) vaccine in a humanized mouse model.

3 Jan 2023

Serine News and Research

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

Understanding the relationship between SARS-CoV-2 infection and periodontitis

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

Altered amino acid metabolism could contribute to diabetes-associated peripheral neuropathy

Researchers identify a key host-cell player in COVID-19 infections

Exploring the infectivity, transmissibility, and immunological resistance characteristics of SARS-CoV-2 Omicron XBB.1.5 strain

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Artemisia argyi plant extracts and phytochemicals shown to inhibit SARS-CoV-2 in new research

The loss of epigenetic information accelerates the aging process

Study on the ecology of viruses in urban rodents with special emphasis on SARS-CoV-2

Comprehensive atlas of protein kinases could help scientists decipher many cellular signaling pathways

Certain type of glial cell plays a major role in spatial learning

Study shows XBB.1.5 exhibits a substantially higher hACE2-binding affinity compared to BQ.1.1 and XBB/XBB.1

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

What is the impact of COVID-19 on the human genetic architecture?

Scientists explore synthesis of griffithsin in cell-free systems

SARS-CoV-2 structural proteins trigger periodontal fibrosis

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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