Severe Acute Respiratory News and Research

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An Omicron wave predicted for England from December 2021 to April 2022

A study, published on the medRxiv* preprint server, focuses on the interaction between Omicron variants and public health interventions in England that promote immunity.

20 Dec 2021

New oral pill for COVID-19 home treatment

As cases and hospitalizations continue to rise in many countries, new treatments are being sought to arrest the progression of the disease, preventing severe illness and death or disability. One such is the small molecule molnupiravir, the focus of a new research paper.

20 Dec 2021

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

A new study posted to the bioRxiv* preprint server aimed to demonstrate whether the loss of the QTQTN motif attenuates SARS-CoV-2 replication in respiratory cells in vitro and pathogenesis in hamsters.

20 Dec 2021

New study suggests most monoclonal antibody treatments are ineffective against Omicron SARS-CoV-2 variant

The arrival of the Omicron (B.1.1.529) variant has brought into question the effectiveness of current COVID-19 treatments in preventing infection and death. New research published in the preprint bioRxiv* server suggests the efficacy of most monoclonal antibody treatments are ineffective against Omicron.

20 Dec 2021

Omicron variant of SARS-CoV-2 exhibits striking antibody evasion

Researchers discuss the likely impact on current convalescent therapies and immunity of vaccinated individuals against the SARS-CoV-2 Omicron variant.

20 Dec 2021

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Researchers study influenza and SARS-CoV-2 infection models to identify lung memory B cells during viral infection.

20 Dec 2021

Long-read RNA sequencing identifies important host immune responses during SARS-CoV-2 infection

Researchers conduct a comprehensive in vitro analysis of relatively unexplored host immune responses during SARS-CoV-2 infection.

20 Dec 2021

White-tailed deer are efficient carriers of SARS-CoV-2

Researchers demonstrate the susceptibility of white-tailed deer to SARS-CoV-2.

20 Dec 2021

Genomic study of furin cleavage sites validates the natural evolutionary origin of SARS-CoV-2 in bats

A team of researchers describes the genomic region encompassing the furin cleavage site in SARS-CoV-2.

20 Dec 2021

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Researchers discuss the sensitivity of the SARS-CoV-2 Omicron variant towards various monoclonal antibodies.

20 Dec 2021

Impact of acute kidney injury associated gene expression in human kidney cells

A new study attempts to perform a comparative single-cell census of human kidneys employing samples from individuals suffering from acute kidney injury and controls without the condition.

20 Dec 2021

SARS-CoV-2 infection leads to distinct changes in proteomic and peptidomic profiles and posttranslational modifications

A new study indicates that as a result of SARS-CoV-2 infection comprehensive changes in protein processing and regulation occur.

20 Dec 2021

Researchers predict 200% increase in European coronavirus cases as Omicron spreads

New algorithms predict how the Omicron variant will spread across 27 countries in the European Union, the United Kingdom, and Switzerland.

20 Dec 2021

COVID-19 infection during pregnancy found to impact infant neurodevelopment

New research suggests that prenatal coronavirus disease 2019 (COVID-19) exposure increases the risk for neurodevelopmental disorders in the baby’s first year of life.

20 Dec 2021

Cloth facemasks worn during exercise are unlikely to cause significant respiratory changes

A new study explored whether wearing masks either increased, reduced, or did not alter various respiratory variables.

20 Dec 2021

Computational analysis of the effect of SARS-CoV-2 Omicron variant spike protein mutations

A new study highlights the potential evolutionary trade-off observed in the omicron variant, detailing the dynamics of the protein structure, its interactions, and subsequent effects.

20 Dec 2021

Anti-SARS-CoV-2 antibody infusion shown to demonstrate robust immune response following COVID-19 vaccination

A new study expands the understanding of the impact of receiving a prophylactic monoclonal antibody infusion, as well as other variables, on the endogenous immune response to complete COVID-19 immunization.

20 Dec 2021

Study suggests SARS-CoV-2 Omicron variant RBM binding may be weaker than in wild-type

A new study shows that the Omicron variant binds to the ACE2 receptor in a significantly weaker manner than other variants and the wild-type.

20 Dec 2021

Impact of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military personnel

A new study helps to explain the rapid spread of the Delta variant and provides the impetus to increase control measures including vaccine boosters and social distancing requirements.

20 Dec 2021

REACT-1 study shows COVID boosters and first doses in children are providing important protection

The Real-time Assessment of Community Transmission-1 (REACT-1) study has been tracking the transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) throughout England since May 2020. SARS-CoV-2 is the cause of the ongoing coronavirus disease 2019 (COVID-19) pandemic.

19 Dec 2021

Severe Acute Respiratory News and Research

An Omicron wave predicted for England from December 2021 to April 2022

New oral pill for COVID-19 home treatment

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

New study suggests most monoclonal antibody treatments are ineffective against Omicron SARS-CoV-2 variant

Omicron variant of SARS-CoV-2 exhibits striking antibody evasion

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Long-read RNA sequencing identifies important host immune responses during SARS-CoV-2 infection

White-tailed deer are efficient carriers of SARS-CoV-2

Genomic study of furin cleavage sites validates the natural evolutionary origin of SARS-CoV-2 in bats

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Impact of acute kidney injury associated gene expression in human kidney cells

SARS-CoV-2 infection leads to distinct changes in proteomic and peptidomic profiles and posttranslational modifications

Researchers predict 200% increase in European coronavirus cases as Omicron spreads

COVID-19 infection during pregnancy found to impact infant neurodevelopment

Cloth facemasks worn during exercise are unlikely to cause significant respiratory changes

Computational analysis of the effect of SARS-CoV-2 Omicron variant spike protein mutations

Anti-SARS-CoV-2 antibody infusion shown to demonstrate robust immune response following COVID-19 vaccination

Study suggests SARS-CoV-2 Omicron variant RBM binding may be weaker than in wild-type

Impact of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military personnel

REACT-1 study shows COVID boosters and first doses in children are providing important protection

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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