Severe Acute Respiratory News and Research

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Loss of taste and smell may be most reliable COVID-19 symptoms for digital surveillance

A team of researchers from various institutions in London, Israel, and the USA recently tested the existence of consistent links between COVID-19 symptoms and SARS-CoV-2 test status in 3 national surveillance platforms.

24 Dec 2020

Mental disorders highly prevalent during coronavirus pandemics

Researchers in the United States have conducted an analysis showing the high prevalence of mental disorders across populations impacted by coronavirus pandemics.

24 Dec 2020

Researchers find correlation between consistent mask-wearing and improved well-being

A team of researchers at the University of Edinburgh, UK, suggest that consistent mask-wearing is associated with better wellbeing.

24 Dec 2020

Higher BMI linked to increased risk of SARS-CoV-2 infection

Researchers at the University of Miami Miller School of Medicine, USA, revealed that the spike-specific immunoglobulin G antibodies in obese people are negatively associated with body mass index (BMI) and serum levels of proinflammatory and metabolic markers of pulmonary inflammation.

24 Dec 2020

How has the COVID19 pandemic affected the well-being of pregnant women?

A new study by researchers at the Department of Women and Children’s Health at Uppsala University, Sweden, aimed to determine the effects of COVID-19 on pregnant women's mental health and well-being.

24 Dec 2020

A common compound in mouthwashes found to inhibit SARS-CoV-2 in vitro

Researchers found that cetylpyridinium chloride, found in most mouthwashes, lowers infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro, likely by inhibiting viral fusion with target cells. With more tests to prove validity, mouthwashes could be a simple, cheap way of curbing transmission.

24 Dec 2020

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

A recent computational study from India implicated a dysregulated vitamin D pathway in the pathobiology of the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and opened the door for experimental validation of these observations.

23 Dec 2020

Frequent and rapid testing may reduce SARS-CoV-2 transmission in carehomes

A team of scientists from the Centers for Disease Control and Prevention, United States, recently conducted a study to evaluate the effectiveness of serial testing and isolation of healthcare personnel in nursing homes in preventing the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19).

23 Dec 2020

Public adherence to COVID-19 guidelines in Norway: a case study

To evaluate and understand the adherence to public health actions recommended by the government, a team in Norway undertook a study funded in part by the Norwegian Research Council’s Centres of Excellence Funding Scheme and by the project: A realtime analytical pipeline for preparedness, planning, and response during the COVID-19 pandemic in Norway.

23 Dec 2020

SARS-CoV-2 mutations may evade T cell immunity

A potentially disturbing new study suggests that SARS-CoV-2 may be undergoing strategic mutations that affect the host immune capacity to recognize and combat the pathogen via T effector cells.

23 Dec 2020

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

A new study sheds light on some important differences between asymptomatic and symptomatic patients with coronavirus disease 2019 (COVID-19).

23 Dec 2020

Researchers use fruit fly model to understand COVID-19-related neurological complications

Researchers claim to have reproduced disease mechanisms due to coronavirus disease 2019 (COVID-19) in the fruit fly, Drosophila, while also providing proof of the efficacy of one drug against these disease processes. If validated, these findings represent a new understanding of how the virus causes neurological symptoms that could help develop more effective therapies.

23 Dec 2020

SARS-CoV-2 antibody levels and types differ by disease severity, study finds

Researchers have measured the antibody levels and types in hospitalized coronavirus disease 2019 (COVID-19) patients with different disease severity. Their results suggest gut immune pathways could play a role in reducing virus-based inflammation and recovery.

22 Dec 2020

What are the potential benefits of SARS-CoV-2 antigen-based rapid diagnostic tests?

A team of researchers from the Johns Hopkins University, USA; Imperial College London, UK; and Foundation for Innovative New Diagnostics, Switzerland, recently compared the effectiveness of Ag-RDT, NAAT, and clinical judgment alone in the diagnosis of COVID-19 in symptomatic patients.

22 Dec 2020

Large-scale study set up in UK to assess possibility of SARS-CoV-2 re-infection among healthcare workers

Researchers from Public Health England are conducting a large-scale prospective longitudinal study to determine whether healthcare workers who have previously developed coronavirus disease 2019 (COVID-19) are immune to reinfection with the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Dec 2020

COVID-19 contact tracing ineffective without timely testing and isolation, study says

A new study by Canada-based researchers has showed that contact tracing is not effective if testing and isolation are delayed.

21 Dec 2020

Nearly half of US hospitals have reached critical care capacity, study finds

A new study by researchers at the Harvard T.H. Chan School of Public Health and Brown University shows that about half of US hospitals have reported reaching critical capacity since September, illustrating the scale of the coronavirus pandemic’s ‘second wave’ and the burden of pressure it has placed on the nation’s healthcare.

21 Dec 2020

Study confirms the feasibility of RT-qPCR on extraction-free inactivated SARS-CoV-2 samples

A new paper reports superior results using an alternative test protocol for RT-qPCR testing for the SARS-CoV-2 virus.

21 Dec 2020

Effective vaccine strategies for New South Wales Australia under different vaccine supply

Researchers say mass immunization will terminate the disease, or immunizing 66% of the population with a 90% efficacy vaccine will achieve herd immunity.

21 Dec 2020

Prior use of renin-angiotensin system inhibitors linked to reduced risk of death in older COVID-19 patients with hypertension

A new study, appearing as a preprint on the medRxiv* server, demonstrates the protective effect of drugs in older COVID-19 patients with hypertension.

21 Dec 2020

Severe Acute Respiratory News and Research

Loss of taste and smell may be most reliable COVID-19 symptoms for digital surveillance

Mental disorders highly prevalent during coronavirus pandemics

Researchers find correlation between consistent mask-wearing and improved well-being

Higher BMI linked to increased risk of SARS-CoV-2 infection

How has the COVID19 pandemic affected the well-being of pregnant women?

A common compound in mouthwashes found to inhibit SARS-CoV-2 in vitro

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

Frequent and rapid testing may reduce SARS-CoV-2 transmission in carehomes

Public adherence to COVID-19 guidelines in Norway: a case study

SARS-CoV-2 mutations may evade T cell immunity

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

Researchers use fruit fly model to understand COVID-19-related neurological complications

SARS-CoV-2 antibody levels and types differ by disease severity, study finds

What are the potential benefits of SARS-CoV-2 antigen-based rapid diagnostic tests?

Large-scale study set up in UK to assess possibility of SARS-CoV-2 re-infection among healthcare workers

COVID-19 contact tracing ineffective without timely testing and isolation, study says

Nearly half of US hospitals have reached critical care capacity, study finds

Study confirms the feasibility of RT-qPCR on extraction-free inactivated SARS-CoV-2 samples

Effective vaccine strategies for New South Wales Australia under different vaccine supply

Prior use of renin-angiotensin system inhibitors linked to reduced risk of death in older COVID-19 patients with hypertension

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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