Severe Acute Respiratory News and Research

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A genome-based comparison of SARS-CoV-2 XBB recombinant and its parental lineage

In a recent study posted to the bioRxiv* preprint server, researchers in Italy performed a genome-based comparison of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) XBB recombinant with its parental lineages.

27 Dec 2022

SHEA advises against COVID screening of asymptomatic patients

Society for Healthcare Epidemiology of America says layers of protection are more effective and have fewer unintended harms

27 Dec 2022

Scientists find key reason for ongoing loss of smell in long-COVID

In a recent study published in the journal Science Translational Medicine, researchers reported that long-term anosmia following coronavirus disease 2019 (COVID-19) could be a result of persistent T-cell mediated inflammation occurring in the olfactory epithelium even after the elimination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the olfactory tissue.

27 Dec 2022

An estimated 19 million US adults living with long-COVID

In a recent study published in the journal Clinical Infectious Diseases, a team of researchers examined the risk factors and prevalence and impact of long coronavirus disease (COVID) among a representative sample of adults in the United States (U.S.) and reported that close to 19 million U.S. adults suffer from long COVID.

26 Dec 2022

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Researchers assessed the inborn abnormalities of 2′-5′-oligoadenylate synthetase (OAS)-ribonuclease L (RNASEL) noted in coronavirus disease 2019 (COVID-19)-associated multisystem inflammatory syndrome in children (MIS-C).

23 Dec 2022

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Researchers evaluated plasma and nasal antibody titers responses induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccinations among United Kingdom (UK) residents.

23 Dec 2022

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

Researchers evaluated plasma samples from individuals vaccinated with a fourth booster dose of mono- or bivalent mRNA SARS-CoV-2 vaccine to evaluate the recognition and neutralization capacity against the ancestral (D614G) strain and the Omicron BQ.1.1 subvariant.

23 Dec 2022

High efficacy of SARS-CoV-2 vaccines in preventing COVID-19 deaths in children and adolescents

A new study evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines in Argentinian children when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron were predominant.

23 Dec 2022

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

A new paper presents preliminary evidence that a new vaccine candidate, designed to boost immunity in already immunized individuals, and containing the adjuvanted Beta spike variant protein antigen, can induce a potent cross-neutralizing antibody response in non-human primate models that is detectable for up to three months.

23 Dec 2022

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

A recent Nature Cancer study documented that individuals with B cell lymphomas (LY) and multiple myeloma (MM) developed potent infection neutralization capabilities against several SARS-CoV-2 variants of concern (VoCs).

22 Dec 2022

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

Researchers assesses the real-world efficacy of the novel bivalent COVID-19 vaccine.

22 Dec 2022

T-cell immunity remains effective against SARS-CoV-2 Omicron subvariants

Omicron subvariants effectively escape B-cell immune responses by modifying neutralizing antibody epitopes.

21 Dec 2022

Dutch study shows the effectiveness of COVID vaccination in reducing hospitalizations

The study, which is currently available in the medRxiv* preprint server, reveals that the COVID-19 vaccination has prevented a large number of hospitalizations during the pandemic.

21 Dec 2022

History of COVID-19 increases risk of fatigue and other long COVID symptoms in adults and children

Researchers observe that COVID-19 patients were at an increased risk of developing certain conditions.

21 Dec 2022

WHO releases a global strategy for infection prevention and control at the 75th World Health Assembly

A recent draft released by the World Health Organization discussed the new global strategy to address the gaps in infection prevention and control (IPC) programs that became apparent after the coronavirus disease 2019 (COVID-19) pandemic.

21 Dec 2022

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

Researchers investigated the mechanisms through which the human common cold Betacoronavirus OC43 (HCoV-OC43) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibit the formation of stress granules.

21 Dec 2022

What are the long-term outcomes of critical COVID-19 patients?

Researchers assessed the long-term outcomes of critically ill coronavirus disease 2019 (COVID-19) patients.

21 Dec 2022

Review on nanoparticles usage for treating thrombosis induced by SARS-CoV-2 infections

Researchers provided an overview of nanomedicine strategies to treat coronavirus disease 2019 (COVID-19)-induced thrombosis.

21 Dec 2022

Age-stratified analysis of COVID-19 severity outcomes among vaccinees and individuals with prior SARS-CoV-2 exposure in Indiana

Researchers assessed the effectiveness of vaccine-conferred immune protection against novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, any-cause visits to hospitals and emergency departments (ED), and deaths in Indiana.

21 Dec 2022

Exploring environmental viral emissions after SARS-CoV-2 Human challenge

A recent study captured the dynamics of pre-symptomatic SARS-CoV-2 emissions and reported the extent, magnitude, and routes of viral transmission are heterogeneous, with nasal mucosa being an important source of viral transmission.

21 Dec 2022

Severe Acute Respiratory News and Research

A genome-based comparison of SARS-CoV-2 XBB recombinant and its parental lineage

SHEA advises against COVID screening of asymptomatic patients

Scientists find key reason for ongoing loss of smell in long-COVID

An estimated 19 million US adults living with long-COVID

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

High efficacy of SARS-CoV-2 vaccines in preventing COVID-19 deaths in children and adolescents

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

T-cell immunity remains effective against SARS-CoV-2 Omicron subvariants

Dutch study shows the effectiveness of COVID vaccination in reducing hospitalizations

History of COVID-19 increases risk of fatigue and other long COVID symptoms in adults and children

WHO releases a global strategy for infection prevention and control at the 75th World Health Assembly

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

What are the long-term outcomes of critical COVID-19 patients?

Review on nanoparticles usage for treating thrombosis induced by SARS-CoV-2 infections

Age-stratified analysis of COVID-19 severity outcomes among vaccinees and individuals with prior SARS-CoV-2 exposure in Indiana

Exploring environmental viral emissions after SARS-CoV-2 Human challenge

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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