Severe Acute Respiratory News and Research

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Study reveals increased immunity evasion by Omicron BA.2.75.2

In a recent study posted to the bioRxiv* preprint server, researchers from ETH Zurich, Imperial College London, and Karolinska Institutet identified increased resistance to antibody-mediated neutralization by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineage BA.2.75.2.

21 Sep 2022

Study shows COVID-19 activity peaks during winter in the United States and Europe

In a recent study posted to the Research Square* preprint server, researchers from Columbia University Mailman School of Public Health, Pfizer Inc, and the University of Iowa assessed the seasonal trends observed in coronavirus disease 2019 (COVID-19) cases, hospitalizations, and deaths.

21 Sep 2022

Clinical and epidemiologic features of SARS-CoV-2 in companion animals

In a recent study posted to the Research Square* preprint server, researchers explored the clinical and epidemiologic characteristics of coronavirus disease 2019 (COVID-19) in dogs and cats.

21 Sep 2022

SARS-CoV-2 generates amyloid in cerebral spinal fluid

In a recent study posted to the bioRxiv* preprint server, an international team of researchers demonstrated amyloid aggregation due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human cerebrospinal fluid (CSF).

20 Sep 2022

No adverse affect on sperm quality 6 to 14 months post BNT162b2 COVID vaccine

A study published in the journal Gamete Biology demonstrates that the mRNA-based coronavirus disease 2019 (COVID-19) vaccine developed by Pfizer/BioNTech is not detrimental to sperm health over a long period post-vaccination.

20 Sep 2022

Vaccination-induced responses for Omicron subvariant neutralization

Researchers summarized existing data on SARS-CoV-2 Omicron variant’s sub-variant (BA.1, BA.1.1, BA.2, BA.2.12.1, BA.3, and BA.4/5) neutralization. They also performed a comparative assessment of cross-neutralizing responses of Omicron subvariants in comparison to the Wuhan-Hu-1 strain (prototype) antigen.

20 Sep 2022

Healthcare systems seem may be ill-equipped to handle high co-circulation of influenza and SARS-CoV-2 in the coming year

In a new study, researchers conducted a community-based prospective cohort study in Managua, Nicaragua, before the winter season when influenza A (H3N2) cases surge in the Northern Hemisphere.

20 Sep 2022

What are the 2-year health outcomes among patients hospitalized for COVID-19 in China?

A recent study assessed the dynamic trajectory of COVID-19 symptom burden as well as symptom persistence in those who survived SARS-CoV-2 infection for two years after being discharged from hospitals.

20 Sep 2022

Neutralizing antibody responses, breakthrough SARS-CoV-2 infections, and symptoms after booster BNT162b2 COVID-19 vaccinations

A new study evaluated neutralizing antibody (nAb) responses against the SARS-CoV-2 Omicron variant induced by booster vaccination with Pfizer-BioNTech’s BNT162b2 messenger ribonucleic acid vaccine.

20 Sep 2022

Regular fish oil consumption found effective in preventing severe COVID-19 outcomes

In a new study, researchers investigated whether regular fish oil use decreased the risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

20 Sep 2022

New mechanistic insights on the origin of SARS-CoV-2-induced neurological disorders

Researchers explored the effect of SARS-CoV-2 exposure on the brain.

20 Sep 2022

The potential of nanobody engineering in the development of SARS-CoV-2 antivirals and diagnostic tools

Researchers investigated nanobody engineering to develop antivirals and diagnostic tools against SARS-CoV-2.

20 Sep 2022

Endogenous exosomes act as decoys for SARS-CoV-2

A recent study published in the journal PLoS Biology discussed exosomes as potential decoys for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

20 Sep 2022

Molecular engineered low-cost highly effective RBD-based COVID vaccine

In a recent study posted to the bioRxiv* preprint server, an international team of researchers developed a second-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor binding domain (RBD) antigen (RBD-J6) by molecular engineering with two additional amino acid (aa) substitutions (S383D and L518D mutations) in a hydrophobic cryptic RBD core epitope to enhance stability and expression against SARS-CoV-2 variants of concern (VOCs).

19 Sep 2022

Study estimates 18 million Americans have long-COVID

In a recent study posted to the medRxiv* preprint server, researchers evaluated the prevalence, risk factors, and impact of post-coronavirus disease (COVID) conditions (PCC) or long COVID on daily activities among adults residing in the United States (US).

19 Sep 2022

O-linked sialoglycans affect SARS-CoV-2 spike cleavage

In a recent study posted to the bioRxiv* preprint server, researchers from Spain, the United Kingdom, and the United States used chemical tools to uncover the molecular details of glycan-mediated modulation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) processing.

19 Sep 2022

Comparative hospitalization and mortality risk in the US population during the Omicron and Delta periods

Researchers compared in-hospital mortality across COVID-19 pandemic periods.

19 Sep 2022

The relationship between antigen concentration and diagnostic test performance for SARS-CoV-2 on different types of samples

Researchers investigated how antigen concentration and viral load in different specimen types affected the performance of SARS-CoV-2 rapid diagnostic tests (RDTs).

19 Sep 2022

Is there any impact of COVID-19 vaccines on the fertility of men and women of reproductive age?

Researchers assessed the impact of SARS-CoV-2 vaccines on human fertility.

19 Sep 2022

Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

In a recent study posted to the bioRxiv* server, researchers at the United States Army Medical Research Institute of Infectious Diseases evaluated the immunogenicity of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) deoxyribonucleic acid (DNA) vaccine, nCOV-S(JET), in rhesus macaques

18 Sep 2022

Severe Acute Respiratory News and Research

Study reveals increased immunity evasion by Omicron BA.2.75.2

Study shows COVID-19 activity peaks during winter in the United States and Europe

Clinical and epidemiologic features of SARS-CoV-2 in companion animals

SARS-CoV-2 generates amyloid in cerebral spinal fluid

No adverse affect on sperm quality 6 to 14 months post BNT162b2 COVID vaccine

Vaccination-induced responses for Omicron subvariant neutralization

Healthcare systems seem may be ill-equipped to handle high co-circulation of influenza and SARS-CoV-2 in the coming year

What are the 2-year health outcomes among patients hospitalized for COVID-19 in China?

Neutralizing antibody responses, breakthrough SARS-CoV-2 infections, and symptoms after booster BNT162b2 COVID-19 vaccinations

Regular fish oil consumption found effective in preventing severe COVID-19 outcomes

New mechanistic insights on the origin of SARS-CoV-2-induced neurological disorders

The potential of nanobody engineering in the development of SARS-CoV-2 antivirals and diagnostic tools

Endogenous exosomes act as decoys for SARS-CoV-2

Molecular engineered low-cost highly effective RBD-based COVID vaccine

Study estimates 18 million Americans have long-COVID

O-linked sialoglycans affect SARS-CoV-2 spike cleavage

Comparative hospitalization and mortality risk in the US population during the Omicron and Delta periods

The relationship between antigen concentration and diagnostic test performance for SARS-CoV-2 on different types of samples

Is there any impact of COVID-19 vaccines on the fertility of men and women of reproductive age?

Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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