Short Chain Fatty Acids News and Research

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Butyrate and propionate are two important short-chain fatty acids (SCFAs) produced in the human gut. They have been shown to have significant immune system effects in the intestinal mucosa, by inducing the differentiation of T-regulatory cells via inhibition of histone deacetylase (HDAC). This enzyme keeps chromatin from unwinding and, therefore, inhibits gene transcription.

Feline gut microbes shed light on obesity treatment for humans

Pet cats may be excellent animal models for the study of obesity origins and treatment in humans, a new study of feline gut microbes suggests – and both species would likely get healthier in the research process, scientists say.

18 Jul 2024

Western diets linked to increased risk of IBD and colorectal cancer

Western diets pose a greater risk of Inflammatory Bowel Disease (IBD) and colorectal cancer, according to a milestone review of what people eat around the world.

18 Jul 2024

Bowel movement frequency is linked to long-term health, study suggests

Everybody poops, but not every day. New research by the Institute for Systems Biology (ISB) suggests bowel movement frequency is linked to long-term health.

16 Jul 2024

Archaea: Unseen players in human microbiome and infectious diseases

Archaea, key players in the human microbiome, are linked to various diseases but their pathogenic potential remains speculative. This study highlights their role in conditions like periodontitis and gastrointestinal infections.

16 Jul 2024

Study links vegetable protein to delayed puberty through gut microbiome changes

A large Chinese study found that high vegetable protein intake is linked to later puberty timing and beneficial gut microbiome changes in children, while high animal protein intake is associated with earlier puberty. The gut microbiome mediates these effects.

2 Jul 2024

Dietary fiber promotes beneficial conversion of tryptophan by gut bacteria

We get healthy dietary fibres from consuming fruits, vegetables, and whole grains. But why are the fibres so good for us? A team of researchers has discovered that dietary fibres play a crucial role in determining the balance between the production of healthy and harmful substances by influencing the behavior of bacteria in the colon.

26 Jun 2024

Human milk banks improve infant health but can't fully replace mother's milk

Scientists investigate human milk banks and their impact on infant health, highlighting differences between donated and maternal milk in gut microbiota and development.

25 Jun 2024

Using microbial community-scale metabolic modeling approach for precision nutrition

Short-chain fatty acids (SCFAs) are beneficial molecules created by the bacteria residing in our gut that are closely tied to improved host metabolism, lower systemic inflammation, better cardiovascular health, lower cancer risk, and more.

24 Jun 2024

Targeting the gut microbiome: A new approach to treating diabetes

Researchers review the role of gut microbiota in the pathogenesis and management of diabetes mellitus.

24 Jun 2024

Study reveals the effects of protein-rich diets on the gut microbiome and overall health

New research has shed light on the effects of protein-rich diets on the gut microbiome and overall health. Despite the increasing protein intake in Western diets, especially among athletes and individuals with obesity, the fate of undigested protein and its impact on human health remains largely unknown.

16 Jun 2024

Gut bacteria turn dietary phytate into health-boosting fatty acids, study shows

Study reveals that human gut bacteria, particularly Mitsuokella jalaludinii, efficiently degrade dietary phytate into short-chain fatty acids, enhancing health benefits through microbial synergy.

12 Jun 2024

Study uncovers gut microbes' role in childhood obesity

Researchers used Mendelian randomization to identify causal links between gut microbes and childhood obesity, revealing key microbial players that influence pediatric adiposity.

10 Jun 2024

Study highlights a dietary strategy for health improvement and weight management

A new study by researchers from Arizona State University and their colleagues highlights a dietary strategy for significant health improvement and weight management.

28 May 2024

Gut microbiota and obesity: New study shows promising results with probiotic and prebiotic intervention

The effect of a low-calorie, sufficient fiber regimen combined with probiotic supplements and physical activity on health, body composition, and physique.

16 May 2024

Metabolomic analysis sheds light on gut microbes' role in cardiovascular disease risk

The effect of gut bacteria on non-high-density lipoprotein cholesterol (non-HDL-c) variations.

14 May 2024

Western diet linked to chronic diseases by gut microbiota disruption

The Western diet disrupts gut microbiota and gut barrier function, increasing the risk of non-communicable chronic diseases through chronic low-grade inflammation.

13 May 2024

Study shows that high Mediterranean dietary adherence lowers systemic inflammation in elders

The relationship between high Mediterranean dietary pattern (MDP) adherence and decreased low-grade systemic inflammation.

7 May 2024

Inulin fiber exacerbates inflammatory bowel disease, study finds

Inulin, a type of fiber found in certain plant-based foods and fiber supplements, causes inflammation in the gut and exacerbates inflammatory bowel disease in a preclinical model, according to a new study by Weill Cornell Medicine investigators.

2 May 2024

Research uncovers Blautia bacteria's crucial role in gut health and disease protection

A low-fiber “Western diet” causes damage to the protective mucus barrier in the gut, and such damage can increase the risk of inflammation and infection.

29 Apr 2024

Cruciferous vegetables may offer new hope for inflammatory bowel disease management

Study evaluates the role of cruciferous vegetables and their bioactive components in mitigating inflammatory bowel disease through in vitro, in vivo, and preliminary clinical investigations, suggesting a promising therapeutic avenue.

21 Apr 2024