Short Chain Fatty Acids News and Research

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Butyrate and propionate are two important short-chain fatty acids (SCFAs) produced in the human gut. They have been shown to have significant immune system effects in the intestinal mucosa, by inducing the differentiation of T-regulatory cells via inhibition of histone deacetylase (HDAC). This enzyme keeps chromatin from unwinding and, therefore, inhibits gene transcription.

Researchers reveal how dietary intervention can help prevent autoimmune disease in mice

Could a change in diet be beneficial to people with autoimmune diseases such as lupus? A Yale-led team of researchers have revealed how a dietary intervention can help prevent the development of this autoimmune disease in susceptible mice.

21 Dec 2018

Gut microbiome plays role in immune system regulation, study finds

Scientist have long known that bacteria in the intestines, also known as the microbiome, perform a variety of useful functions for their hosts, such as breaking down dietary fiber in the digestive process and making vitamins K and B7.

19 Dec 2018

Maryland researchers receive grant to study the brain-to-gut connection in schizophrenia

Researchers at the University of Maryland School of Medicine's Maryland Psychiatric Center and Institute for Genome Sciences, along with researchers at the University of Maryland School of Pharmacy, have been awarded a collaborative five-year $1.78 million grant to study the brain-to-gut connection in schizophrenia.

5 Dec 2018

Live probiotics can change existing gut flora and alter immune response

New research published in the International Journal of Pharmaceutics demonstrates that 'good' bacteria in the live probiotic SymproveTM can successfully reach and colonize the gut, where they go on to change the existing gut flora. They are also capable of modifying immune response.

20 Nov 2018

Cranberry consumption modifies impact of animal-based diet on gut health

In a recently published feeding trial in The Journal of Nutritional Biochemistry, scientists investigated the potential protective effect of cranberries on the gut microbiome with an animal-based diet.

13 Nov 2018

Study finds link between refined soluble fibers, gut microbiota and liver cancer

Many of the processed foods we find on grocery store shelves have been loaded up with highly refined soluble fibers such as inulin, a popular probiotic that recently received approval from the Food and Drug Administration to be marketed as health-promoting.

19 Oct 2018

Healthy gut microbiome shown to be important for recovery after heart attack

The community of microorganisms that live in the human gut has been shown to confer all kinds of health benefits. Now, an international team of researchers has shown in mice that a healthy gut microbiome is important for recovery after a heart attack.

10 Oct 2018

Cancer undercuts ability of normal cells to consume glucose, finds study

Cancer needs energy to drive its out-of-control growth. It gets energy in the form of glucose, in fact consuming so much glucose that one method for imaging cancer simply looks for areas of extreme glucose consumption - where there is consumption, there is cancer.

29 Sep 2018

Antibiotics actually kill 'good' bacteria and worsen oral infection, finds study

New research shows that the body's own microbes are effective in maintaining immune cells and killing certain oral infections.

26 Sep 2018

UNC scientists reveal new approach to prevent obesity and diabetes

Scientists from the UNC School of Medicine discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet.

19 Sep 2018

Dietary fiber may delay memory loss, brain inflammation during old age

As mammals age, immune cells in the brain known as microglia become chronically inflamed. In this state, they produce chemicals known to impair cognitive and motor function.

14 Sep 2018

Scientists develop probiotic 'cocktail' derived from infant feces

Probiotics seem to be everywhere these days - in yogurt, pickles, bread, even dog food. But there's one place that may surprise you: There are probiotics in dirty diapers.

23 Aug 2018

Eating white button mushrooms could improve regulation of glucose in the liver

Eating white button mushrooms can create subtle shifts in the microbial community in the gut, which could improve the regulation of glucose in the liver, according to a team of researchers.

16 Aug 2018

Study highlights impact of silent viruses on how the host responds to vaccines

UC Davis researchers have shown that low levels of cytomegalovirus (CMV) have a significant impact on microbe and immune cell populations and how the immune system responds to the influenza vaccine. The study was published in the Journal of Virology.

3 Aug 2018

Eating high fiber foods may decrease effects of stress on gut and behavior

Eating high fiber foods may reduce the effects of stress on our gut and behavior, according to new research published in The Journal of Physiology.

1 Aug 2018

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

The brains of people with Alzheimer's disease contain many protein aggregates outside of cells, known as plaques. These are mainly made of the peptide amyloid-beta, which is released from the plasma membrane when the protease BACE1 cleaves its membrane-anchored precursor protein.

19 Jul 2018

New study reveals how ‘good’ bacteria help in regulating our metabolism

Research tells us that the commensal or "good" bacteria that inhabit our intestines help to regulate our metabolism.

22 Jun 2018

Replacing potatoes or rice with lentils can reduce blood glucose levels, study shows

Replacing potatoes or rice with pulses can lower your blood glucose levels by more than 20 per cent, according to a first-ever University of Guelph study.

13 Jun 2018

Mangos found to be more effective in reducing symptoms of constipation

Next time you suffer from constipation, you may want to consider grabbing a mango instead of reaching for a fiber supplement, suggests a new Texas A & M University pilot study published in the peer-reviewed journal Molecular Nutrition and Food Research.

6 Jun 2018

OSU biologist describes 'restoration ecology' approach toward patient health

Chronic diseases like cancer, autoimmune disorders and obesity may ultimately vanquish the efforts of medical intervention unless people change their diet, an Oregon State University biologist argues in a paper published this week.

26 May 2018