Short Chain Fatty Acids News and Research

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Butyrate and propionate are two important short-chain fatty acids (SCFAs) produced in the human gut. They have been shown to have significant immune system effects in the intestinal mucosa, by inducing the differentiation of T-regulatory cells via inhibition of histone deacetylase (HDAC). This enzyme keeps chromatin from unwinding and, therefore, inhibits gene transcription.

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023

Age and sex determine the effects of microbiota on mice's metabolome

The gut handles all ingested foods for further digestion and assimilation. In addition, it harbors a wealth of microbes that produce metabolic byproducts with multiple effects on host physiology. Therefore, changes in the gut microbiome's composition can shift the gut's metabolome as well.

15 Mar 2023

How gut microbiota control feelings of fullness after eating

A recent study discusses recent findings linking satiety to the gut microbiome.

7 Mar 2023

Gut bacteria influence the liver's regenerative ability

When parts of the liver are removed, the body can replace the missing tissue. A team of researchers at the Technical University of Munich has now discovered that the success of this process depends to a large extent on gut bacteria.

1 Mar 2023

Immunomodulatory effects of biotics-supplemented infant formulas

A review article published in the journal Nutrients describes the effects and benefits of pre-, pro-, syn-, and postbiotics-containing infant formulas in terms of modulating gut microbiota, immune response, and allergy susceptibility of newborns and infants.

1 Mar 2023

Three intestinal bacteria associated with dementia with Lewy bodies discovered

Dementia with Lewy bodies (DLB), one of the most common forms of dementia, has no cure. Previous studies suggested that gut bacteria, the microorganisms that live in the human digestive tract, play a role in Parkinson's disease, another neurodegenerative disorder, but the bacteria involved in DLB had not been identified.

28 Feb 2023

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers highlight recent research investigating whether gut microbiota regulates tau pathology and tau-mediated neurodegeneration in an ApoE isoform–dependent manner.

21 Feb 2023

How the human gut microbiota is shaped by diet

A new study in the journal Best Practice & Research Clinical Gastroenterology aimed to summarize the impact of specific nutrients as well as diets on the gut microbiota as well as the future perspectives of using diet as a therapeutic microbiome modulator.

20 Feb 2023

Changing dietary fiber structure promotes healthy gut bacteria and reduces gas formation

Changing the structure of a dietary fiber commonly found in a range of food products has been found to promote healthy gut bacteria and reduce gas formation, a finding that could help people with intolerances to fiber and irritable bowel conditions.

16 Feb 2023

Reduced butyrate production in the microbiome of type 2 diabetics

Researchers observe reduced levels of butyrate-producing bacteria in the microbiome of type 2 diabetics.

15 Feb 2023

How does previous diet impact the endocannabinoidome and microbiome response to a short-term Mediterranean diet intervention?

Researchers assessed the different impacts of diet on the gut microbiome.

15 Feb 2023

Research examines whether meat or dairy-based complementary foods affect gut microbiota and growth

A new study in the journal Frontiers in Nutrition aimed to analyze the impact of complementary foods on the development of infant gut microbiota and whether it is associated with infant growth.

14 Feb 2023

Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

Researchers determine the association between diet, microbe-derived metabolites, and cytokine levels with anxiety and depression among obese adults.

6 Feb 2023

New insights into the release of microplastics from breastmilk storage bags

Researchers from China analyzed the quantity, size, and composition of microplastics and other particle matter released into breastmilk from disposable breastmilk storage bags.

6 Feb 2023

How eating patterns and nutritional intake affects the management of type 2 diabetes

The main goal of this review is to provide evidence-based dietary guidelines for patients looking to manage their diabetes.

1 Feb 2023

Researchers report on a genome-wide reconstruction of human microbes to develop personalized therapies

Researchers reported on AGORA2, an expansion of their previously published resource, AGORA, of genomewide metabolic reconstructions of human intestinal microbes.

26 Jan 2023

Immunological interactions between asthma, obesity, and the microbiota

This study summarizes the mechanisms associated with obesity-aggravated asthma.

18 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

A growing pile of evidence indicates that the tens of trillions of microbes that normally live in our intestines -; the so-called gut microbiome -; have far-reaching effects on how our bodies function.

12 Jan 2023

Current research on gut microbial modulation with culinary herbs and spices

An article published in Food Chemistry elaborated on the health benefits of culinary herbs and spices.

5 Jan 2023