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IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

New topical drug shows promise in preventing cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma is the second most common type of skin cancer in the United States, impacting approximately 700,000 people each year.

11 Oct 2023

Scientists identify nearly a dozen genes responsible for coronary artery calcification

An international team of scientists has identified nearly a dozen genes that contribute to calcium buildup in our coronary arteries that can lead to life-threatening coronary artery disease, a condition responsible for up to one in four deaths in the United States.

11 Oct 2023

DNA aptamers: A versatile tool for regenerative medicine and beyond

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

10 Oct 2023

Macrophages play a central role in intestinal cell renewal, study reveals

A research team from MedUni Vienna and the FWF-sponsored Special Research Area SFB F83 Immunometabolism has now demonstrated for the first time the central role of macrophages in the renewal of intestinal cells, which sheds light on the complex interplay between immune cells and tissue regeneration.

10 Oct 2023

Discovery of a novel therapeutic target for pancreatic cancer

A novel amino acid transporter-based therapeutic target for pancreatic ductal adenocarcinoma (PDAC).

10 Oct 2023

Drug combo safely decreases pancreatic cancer growth in mice

A new combination of treatments safely decreased growth of pancreatic cancer in mice by preventing cancer cells from scavenging for fuel, a new study finds.

9 Oct 2023

Study uncovers novel therapeutic target for osteoblastic lesions in prostate cancer bone metastasis

In a study published in the journal Genes & Diseases, researchers from Army Medical University and Shenzhen University investigated the pivotal role of miR-18a-5p, a microRNA, in the development and progression of osteoblastic lesions resulting from prostate cancer (PCa) bone metastasis.

9 Oct 2023

EMC1 protein found to play pivotal role in retinal vascular development

In a groundbreaking study published in the journal Genes & Diseases, researchers from University of Electronic Science and Technology of China have uncovered a key relationship between the EMC1 protein and retinal vascular development.

9 Oct 2023

Study sheds light on PRMT1's role in gastric cancer progression

In a study published in the journal Genes & Diseases, researchers from Southwest University, and Southwest Medical University investigated PRMT1, a protein previously known to be overexpressed in gastric cancer cells.

9 Oct 2023

Effectiveness of Lactobacillus in treating inflammatory bowel disease

The role of Lactobacillus in treating inflammatory bowel disease.

4 Oct 2023

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

The connection between the CHD gene and autism-related gastrointestinal (GI) manifestations.

4 Oct 2023

Could plant-based phytonutrients be the secret weapon against obesity?

This comprehensive review in the journal Foods explores the therapeutic potential of phytonutrients in combating obesity. The paper delves into various plant-based compounds like polyphenols, alkaloids, and terpenoids, detailing their mechanisms of action in inhibiting fat accumulation, regulating metabolism, and even altering gut microbiota.

1 Oct 2023

Study reveals new insights into how the immune system prevents autoimmunity

Researchers at Stanford University School of Medicine, Yale University School of Medicine, and the Hospital for Special Surgery Research Institute have uncovered new details about how the immune system prevents the production of antibodies that can recognize and damage the body's own, healthy tissues.

29 Sep 2023

Racial disparities in survival rates among patients with multiple myeloma and diabetes

Patients with multiple myeloma, a blood cancer of plasma cells in the bone marrow, who also have diabetes have a reduced overall survival when compared to those without diabetes.

29 Sep 2023

Blocking Notch signaling pathway could reverse age-related bone loss

A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.

27 Sep 2023

Study identifies four novel receptors potentially linking endometrial cancer with PCOS

A new research paper was published in Oncotarget's Volume 14 on September 22, 2023, entitled, "Transcriptomic analysis identifies four novel receptors potentially linking endometrial cancer with polycystic ovary syndrome and generates a transcriptomic atlas."

25 Sep 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023

AlphaMissense revolutionizes genetic mutation analysis for disease prediction

AlphaMissense, an adaptation of AlphaFold, offers a highly accurate model for predicting the pathogenicity of human proteome-wide missense variants at the single amino acid level. The model outperforms existing methods, providing valuable insights for diagnosing rare diseases and developing targeted therapies.

20 Sep 2023

HNP-1 may be a promising therapeutic agent for hypertensive left ventricular hypertrophy

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Human neutrophil peptide-1 (HNP-1) is a commonly investigated therapeutic agent.

14 Sep 2023