Signaling Pathway News and Research

RSS

Oncolytics Biotech reports new findings at ASCO’s 2013 Gastrointestinal Cancers Symposium

What did Pope John Paul II, Ronald Reagan and Robin Gibb of the Bee Gees have in common? Each was diagnosed with colorectal cancer, the third most commonly diagnosed cancer in the world and the fourth most common cause of cancer death.

29 Jan 2013

DRCRF announces recipients of Nov. 2012 Damon Runyon Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 15 new Damon Runyon Fellows at its fall Fellowship Award Committee review.

29 Jan 2013

Emotional stress can reduce prostate cancer drugs’ effectiveness

Not surprisingly, a cancer diagnosis creates stress. And patients with prostate cancer show higher levels of anxiety compared to other cancer patients. A new study by researchers at Wake Forest Baptist Medical Center indicates that stress is not just an emotional side effect of the diagnosis; it also can reduce the effectiveness of prostate cancer drugs and accelerate the development of prostate cancer.

29 Jan 2013

Temple scientists to solve long-standing mystery in sepsis

Scientists at the Center for Translational Medicine at the Temple University School of Medicine are inching closer to solving a long-standing mystery in sepsis, a complex and often life-threatening condition that affects more than 400,000 people in the U.S. every year.

28 Jan 2013

Researchers identify signaling pathway used by malarial parasites to destroy host cells

One of the most insidious ways that parasitic diseases such as malaria and toxoplasmosis wreak their havoc is by hijacking their host's natural cellular processes, turning self against self.

18 Jan 2013

Some epileptic seizures may originate in glia: Study

Epileptic seizures occur when neurons in the brain become excessively active. However, a new study from MIT neuroscientists suggests that some seizures may originate in non-neuronal cells known as glia, which were long believed to play a mere supporting role in brain function.

17 Jan 2013

Fifteen established scientists to receive NARSAD Distinguished Investigator Grants

The Brain & Behavior Research Foundation (formerly NARSAD, the National Alliance for Research on Schizophrenia and Depression) announced the latest recipients of its highly competitive NARSAD Distinguished Investigator Grants.

16 Jan 2013

New hope for people with sound-induced deafness

Preliminary results from a study in mice suggest it may be possible to regenerate cochlear hair cells that have been damaged due to excessive noise exposure.

15 Jan 2013

Mayo Clinic researchers identify new target to improve treatment of pancreatic cancer

Researchers at Mayo Clinic in Florida have identified a new target to improve treatment of pancreatic ductal adenocarcinoma cancer, which accounts for more than 95 percent of pancreatic cancer cases. This fast-growing, often lethal cancer is resistant to conventional chemotherapy.

4 Jan 2013

Novel approach to sort out good or bad mutations associated with lymphoma

As anyone familiar with the X-Men knows, mutants can be either very good or very bad - or somewhere in between. The same appears true within cancer cells, which may harbor hundreds of mutations that set them apart from other cells in the body; the scientific challenge has been to figure out which mutations are culprits and which are innocent bystanders.

28 Dec 2012

Study finds new signaling pathway involved in development of chronic inflammation of brain cells

The number of Alzheimer's patients will continue to dramatically increase in the next several decades. Various teams of researchers worldwide are feverishly investigating precisely how the illness develops. A

20 Dec 2012

Everolimus therapy might treat Myc-driven lymphoma

Drugs that are used in the clinic to treat some forms of breast and kidney cancer and that work by inhibiting the signaling molecule mTORC1 might have utility in treating some of the more than 15 percent of human cancers driven by alterations in the Myc gene, according to data from a preclinical study published in Cancer Discovery, a journal of the American Association for Cancer Research.

15 Dec 2012

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They say the finding could lead to a new treatment for prostate cancers that are no longer controlled by hormone-blocking drugs.

14 Dec 2012

Surprising discovery about physical properties of cancer cells

A surprising discovery about the physical properties of cancer cells could help improve a new diagnostic approach - a liquid biopsy - that detects, measures, and evaluates cancer cells in blood.

5 Dec 2012

microRNAs play an important role during embryonic development

Sanford-Burnham researchers discover that microRNAs play an important role in germ layer formation-the process that determines which cells become which organs during embryonic development

3 Dec 2012

Selumetinib plus docetaxel shows KRAS-mutant NSCLC potential

The addition of selumetinib to docetaxel therapy may boost the survival of patients with KRAS-mutant non-small-cell lung cancer, suggest study findings published in The Lancet Oncology.

3 Dec 2012

Gadd45g protein essential in initiating development of male sex organs

Scientists at the Institute of Molecular Biology (IMB) in Mainz have identified a protein essential for initiating the development of male sex organs. Loss of the gene Gadd45g results in complete sex reversal of male mice, making them appear female.

28 Nov 2012

Nonfunctional MED12 gene linked to chemotherapy resistance

Research published in Cell shows that people with tumors that have a nonfunctional version of the mediator 12 gene are resistant to drugs used to treat lung and colon cancer such as gefitinib.

26 Nov 2012

Researchers reveal molecular mechanisms that lead to basal cell carcinoma initiation

Advanced online publication in Nature Cell Biology: Researchers at the Université libre de Bruxelles, uncover the molecular mechanisms leading to basal cell carcinoma initiation.

26 Nov 2012

TGF-betaR inhibitors may counter drug resistance in cancer patients with MED12 mutations

Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a study published by Cell Press November 21st in the journal Cell.

22 Nov 2012

Signaling Pathway News and Research

Oncolytics Biotech reports new findings at ASCO’s 2013 Gastrointestinal Cancers Symposium

DRCRF announces recipients of Nov. 2012 Damon Runyon Fellows

Emotional stress can reduce prostate cancer drugs’ effectiveness

Temple scientists to solve long-standing mystery in sepsis

Researchers identify signaling pathway used by malarial parasites to destroy host cells

Some epileptic seizures may originate in glia: Study

Fifteen established scientists to receive NARSAD Distinguished Investigator Grants

New hope for people with sound-induced deafness

Mayo Clinic researchers identify new target to improve treatment of pancreatic cancer

Novel approach to sort out good or bad mutations associated with lymphoma

Study finds new signaling pathway involved in development of chronic inflammation of brain cells

Everolimus therapy might treat Myc-driven lymphoma

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

Surprising discovery about physical properties of cancer cells

microRNAs play an important role during embryonic development

Selumetinib plus docetaxel shows KRAS-mutant NSCLC potential

Gadd45g protein essential in initiating development of male sex organs

Nonfunctional MED12 gene linked to chemotherapy resistance

Researchers reveal molecular mechanisms that lead to basal cell carcinoma initiation

TGF-betaR inhibitors may counter drug resistance in cancer patients with MED12 mutations

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News