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New insights into lymphatic cell migration and lymphatic vessel remodeling

Lymphangiogenesis refers to the formation and remodeling of lymphatic vessels (a network of thin tubes that carry lymph in the lymphatic system), and it supports the transport of molecules and immune cells around the body.

21 Jun 2023

New treatment could be instrumental in restoring the blood-brain barrier's normal function

There's a bouncer in everyone: The blood-brain barrier, a layer of cells between blood vessels and the rest of the brain, kicks out toxins, pathogens and other undesirables that can sabotage the brain's precious gray matter.

20 Jun 2023

Study reveals a co-pathogenesis mechanism of acute myocardial infarction and ulcerative colitis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Cardiovascular diseases, particularly acute myocardial infarction, are the leading cause of disability and death.

15 Jun 2023

Mutations that lead to intracranial aneurysms discovered

Researchers at the RIKEN Center for Brain Science (CBS) in Japan have discovered a set of related mutations that lead to intracranial aneurysms-;weakened blood vessels in the brain that can burst at any time.

14 Jun 2023

First-in-class drug shows promise as a safe and effective treatment for cannabis use disorder

A first-in-class drug engineered to selectively inhibit the signaling pathway of the cannabinoid receptor shows promise as a safe and effective treatment for cannabis use disorder (CUD), a condition where a person is unable to control their cannabis use, even though it's causing problems in their lives.

8 Jun 2023

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

Obesity strikes below the belt: Study reveals link between obesity and male infertility

The influence of obesity on male fertility is still under debate. In the present investigation, researchers scrutinized semen samples from both obese individuals and those of normal weight. The aim was to explore the relationship between obesity, the length of sperm telomeres, levels of mRNA associated with autophagy, and diverse semen characteristics.

29 May 2023

Japanese natto consumption may help realize a healthy and longer-living society

Health is wealth as the saying goes and new research now shows that it is possible to have a healthy, less stressed society through familiar and inexpensive foods.

26 May 2023

Treatment with luspatercept improves red blood cell counts in patients with myelodysplastic syndromes

Treatment with luspatercept improved red blood cell counts and erythroid responses compared to treatment with epoetin alfa in patients with myelodysplastic syndromes (MDS), allowing the majority to no longer require regular blood transfusions.

26 May 2023

Curcumin can suppress metastasis of colorectal cancer cells by activating a specific signaling pathway

LMU researchers have identified a signaling pathway via which curcumin can suppress the metastasis of colorectal cancer cells.

25 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

Study offers hope for better recovery of stroke patients

Ischemic stroke, caused by a blockage of blood flow to the brain, is a common cause of death and disability.

11 May 2023

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

In a recent study published in the journal Cell Stem Cell, researchers hypothesized that pacemaker-like activity of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) resulted in engraftment arrhythmias (EAs), which hampers the clinical use of cell-based therapy using hPSC-CMs for treatment of myocardial infarction (MI).

2 May 2023

Signaling Pathway News and Research

New insights into lymphatic cell migration and lymphatic vessel remodeling

New treatment could be instrumental in restoring the blood-brain barrier's normal function

Study reveals a co-pathogenesis mechanism of acute myocardial infarction and ulcerative colitis

Mutations that lead to intracranial aneurysms discovered

First-in-class drug shows promise as a safe and effective treatment for cannabis use disorder

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Obesity strikes below the belt: Study reveals link between obesity and male infertility

Japanese natto consumption may help realize a healthy and longer-living society

Treatment with luspatercept improves red blood cell counts in patients with myelodysplastic syndromes

Curcumin can suppress metastasis of colorectal cancer cells by activating a specific signaling pathway

Newly identified genetic variant provides protection from Alzheimer's disease

Study offers hope for better recovery of stroke patients

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

The role of diet in managing type 2 diabetes: insights into individualized medical nutritional therapy

Researchers identify a druggable copper-signaling pathway that drives inflammation

Study sheds light on immune factors responsible for contrasting SARS-CoV-2 outcomes in humans and white-tailed deer

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Exploring the tantalizing questions about sleep

Dietary supplement N-acetylcysteine helps overcome treatment resistance in breast cancer

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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