Small Cell Lung Cancer News and Research

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Small cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung. Small cell lung cancer is an aggressive (fast-growing) cancer that can spread to other parts of the body. The cancer cells look small and oval-shaped when looked at under a microscope.

Lung cancer may soon be picked up by a blood test

A study presented at the ESMO Congress 2019 has revealed that a blood test may soon be able to pick up circulating tumor DNA to help avoid invasive tissue biopsies in lung cancer patients.

30 Sep 2019

Higher levels of genetic mutations linked to improved outcomes in lung cancer patients

According to new findings by Yale Cancer Center scientists, higher levels of genetic mutations in a tumor biopsy are linked to improved clinical outcomes in patients using pembrolizumab (Keytruda) to treat non-small cell lung cancer (NSCLC).

27 Sep 2019

Adding radiation after immunotherapy increases PFS for some patients with metastatic NSCLC

Adding precisely aimed, escalated doses of radiation after patients no longer respond to immunotherapy reinvigorates the immune system in some patients with metastatic non-small-cell lung cancer, increasing progression-free survival.

26 Sep 2019

Tasmanian devil study may give clues to how cancers evade the immune system

A cluster of interacting proteins that are active in both human cancers and Tasmanian devil facial tumors, may give clues to how cancers evade the immune system, according to a study part-funded by Cancer Research UK and published in Cancer Cell today.

26 Sep 2019

Investigational drug may offer new treatment option for patients with lung and kidney cancer

Pegilodecakin, a first-in-class drug currently in clinical trials, has shown positive safety results and may offer a potential new treatment avenue for patients with non-small cell lung cancer (NSCLC) and kidney cancer.

26 Sep 2019

Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer

Scientists have developed a method which is able to switch ‘tumor suppressor’ genes back on after they have been silenced by cancer cells.

25 Sep 2019

Pembrolizumab provides added benefit for subpopulations of patients with metastatic NSCLC

In early July, the German Institute for Quality and Efficiency in Health Care conducted two early benefit assessments to investigate whether certain drug combinations with pembrolizumab have advantages in comparison with the respective appropriate comparator therapy for patients with metastatic squamous or non-squamous non-small cell lung cancer.

20 Sep 2019

Scientists identify pathway for treatment-resistant lung cancer

A big way chemotherapy works is by prompting cancer cells to commit suicide, and scientists have found a pathway the most common lung cancer walks to avoid death.

20 Sep 2019

Low-dose aspirin may improve survival in patients with head and neck, lung cancers

What if a drug that sits in nearly everyone's medicine cabinet could help extend the lives of some cancer patients? In companion presentations at the American Society for Therapeutic Radiation Oncology Annual Meeting in Chicago, doctors from Roswell Park Comprehensive Cancer Center report new evidence that low-dose aspirin and other anti-inflammatories may improve survival in patients undergoing treatment for some head/neck and lung cancers.

19 Sep 2019

Mutations linked with sensitivity or resistance to immunotherapy in mNSCLC

The relationship between gene alterations and response to anti-PD-L1 with and without anti-CTLA-4 are not well characterized.

10 Sep 2019

New drug combination shows promise for treating non-small cell lung cancer patients

Patients with non-small cell lung cancer now have more improved treatment options compared to standard of care with the addition of several new agents called immune-checkpoint inhibitors.

27 Aug 2019

Super-powered immune cells to attack tumors

Ground-breaking immune therapy promises to deliver vital evidence in the fight against cancer as researchers from the Centre for Cancer Biology open a new clinical trial using genetically engineered immune cells to treat solid cancers.

23 Aug 2019

Dacomitinib treatment for lung cancer increases overall survival but has more side effects

Since its approval in April 2019, dacomitinib has been available for the first-line treatment of adult patients with locally advanced or metastatic non-small cell lung cancer with epidermal growth factor receptor activating mutations.

20 Aug 2019

Preliminary study for detection of pancreatic cancer shows encouraging results

OTraces, Inc., a molecular diagnostics company specializing in early cancer detection, has announced completion of a preliminary study for detection of pancreatic cancer.

1 Aug 2019

Alternate cell growth pathway could open door to new treatments for metastatic cancers

While researchers have a basic understanding of how primary cancer cells grow, less is known about metastasis, the deadly process by which cancers spread.

12 Jul 2019

Adding immunotherapy after initial treatment improves survival in metastatic NSCLC patients

Treating metastatic non-small cell lung cancer patients with the immunotherapy drug pembrolizumab after they've completed locally ablative therapy – meaning all known sites of their cancer were either treated with surgery, radiation, or other definitive treatments – almost tripled the median progression-free survival compared to the historical average.

12 Jul 2019

Immune system could be blamed for ineffectiveness of high-dose radiation against lung cancer

When it comes to using radiation against lung cancer, preliminary clinical studies were pretty clear: More is better.

27 Jun 2019

Three beagles successfully identify lung cancer by scent, shows study

Three beagles successfully showed they are capable of identifying lung cancer by scent, a first step in identifying specific biomarkers for the disease.

18 Jun 2019

Radiation associated with increased risk of adverse cardiac events in lung cancer patients

As advances in the treatment of non-small cell lung cancer (NSCLC) extend patients' lives, more of these patients are facing a different threat: adverse cardiovascular events, such as heart attacks and heart failure.

11 Jun 2019

Roche Diagnostics launches first in vitro diagnostic ROS1 immunohistochemistry assay

Roche Diagnostics today announced the launch of the VENTANA ROS1 Antibody, the first and only in vitro diagnostic ROS1 immunohistochemistry assay. The test detects the presence of ROS1 protein in tissue, and may be useful in identifying ROS1-positive lung cancer cases.

From Roche Sequencing and Life Science 10 Jun 2019

Small Cell Lung Cancer News and Research

Lung cancer may soon be picked up by a blood test

Higher levels of genetic mutations linked to improved outcomes in lung cancer patients

Adding radiation after immunotherapy increases PFS for some patients with metastatic NSCLC

Tasmanian devil study may give clues to how cancers evade the immune system

Investigational drug may offer new treatment option for patients with lung and kidney cancer

Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer

Pembrolizumab provides added benefit for subpopulations of patients with metastatic NSCLC

Scientists identify pathway for treatment-resistant lung cancer

Low-dose aspirin may improve survival in patients with head and neck, lung cancers

Mutations linked with sensitivity or resistance to immunotherapy in mNSCLC

New drug combination shows promise for treating non-small cell lung cancer patients

Super-powered immune cells to attack tumors

Dacomitinib treatment for lung cancer increases overall survival but has more side effects

Preliminary study for detection of pancreatic cancer shows encouraging results

Alternate cell growth pathway could open door to new treatments for metastatic cancers

Adding immunotherapy after initial treatment improves survival in metastatic NSCLC patients

Immune system could be blamed for ineffectiveness of high-dose radiation against lung cancer

Three beagles successfully identify lung cancer by scent, shows study

Radiation associated with increased risk of adverse cardiac events in lung cancer patients

Roche Diagnostics launches first in vitro diagnostic ROS1 immunohistochemistry assay

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

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