Small Intestine News and Research

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Fecal transplants could be used as treatment for non-alcoholic fatty liver disease

A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease.

9 Jun 2020

New insights into how parenteral oil emulsions prevent liver disease in preterm babies

Infants born prematurely may require parenteral or intravenous nutrition to provide the necessary nourishment, as their digestive system is immature and cannot digest nutrients.

4 Jun 2020

How COVID-19 affects the nervous system

A new paper published in the journal JAMA Neurology in May 2020 discusses the presentation and complications of COVID-19 with respect to the nervous system.

31 May 2020

How susceptible are domestic animals to SARS-CoV-2?

A recent paper by Chinese researchers, published in the leading journal Science, shows that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) does not replicate well in dogs, pigs, chickens, and ducks; however, ferrets and cats are easily infected, and cats may transmit the virus via an airborne route.

31 May 2020

Changes in gut mucus are linked to brain disorders

Mucus is the first line of defense against bad bacteria in our gut. But could it also be part of our defense against diseases of the brain?

29 May 2020

Fibroblasts of different pancreatic diseases exhibit distinct properties, study reveals

Fibroblasts present in different pancreatic diseases are genetically distinct and their functions are 'programmed' by the unique environment of each disease, according to new research from the University of Liverpool (UK).

18 May 2020

Potential for COVID-19 transmission from human eye

A new study published on the preprint server bioRxiv* in May 2020 reports the presence of ACE2 receptors in the eye at high concentrations. These molecules are the entry points for the SARS-CoV-2 virus that is causing the ongoing COVID-19 pandemic.

12 May 2020

Study: Diarrhea-causing bacteria provoke host's response to increase infectivity

A type of E. coli bacteria that causes bloody diarrhea uses an amino acid produced by the body in response to infection to intensify its symptoms, according to a new study from UT Southwestern scientists.

12 May 2020

Study finds bowel abnormalities in patients with COVID-19

Patients with COVID-19 can have bowel abnormalities, including ischemia, according to a new study published today in the journal Radiology.

11 May 2020

Predicting the dose for repurposing nitazoxanide in COVID-19

A new study published on the preprint server medRxiv in May 2020 reports a model that could help evolve appropriate dosage protocols for future clinical trials of the repurposed drug nitazoxanide in COVID-19 prevention and treatment. The researchers say, “It was possible to achieve plasma and lung tizoxanide concentrations, using proven safe doses of nitazoxanide, that exceed the EC90 for SARS-CoV-2.”

7 May 2020

Study explores the growth rate effect of gut bacteria on break down of dietary fibers

It is known that approximately 80% of human immune system functions in the gastrointestinal tract. Gut bacteria and their metabolites play a fundamental role in the interaction between gut and other organs.

29 Apr 2020

Research offers clues to how SARS-CoV-2 gets into respiratory tissue and exploits our defenses

What makes SARS-CoV-2, the virus behind COVID-19, such a threat? A new study, led by Jose Ordovas-Montanes, Ph.D. at Boston Children's Hospital and Alex K. Shalek, Ph.D. at MIT, pinpoints the likely cell types the virus infects.

22 Apr 2020

Study shows how interactions between microbiome and the immune system contribute to liver disease

A new study by researchers in the Quadram Institute has provided insights into how interactions between gut microbes and cells of the immune system contribute to cholestatic liver disease.

20 Apr 2020

New study raises red flags about strategy to block cancer drug resistance

Sooner or later, most cancer patients develop resistance to the very chemotherapy drugs designed to kill their cancer, forcing oncologists to seek alternatives.

17 Apr 2020

New therapeutic approach for preserving inflammation-free phases of Crohn's disease

Intestinal stem cell metabolism is facilitated by mitochondria - the in-cell power plants. Chronic inflammation processes inhibit the cells' metabolism and lead to functional loss of these stem cells.

15 Apr 2020

Alzheimer's patients may need modified dosing regimens for selected drugs

Patients with Alzheimer's disease are often prescribed drugs for other conditions -- including diabetes or high blood pressure -- at the same doses as those without dementia.

15 Apr 2020

Bacterial metabolism of bile acids boosts generation of immune cells, study shows

A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells--immune cells that suppress autoimmune reactions and inflammation.

15 Apr 2020

Cats, ferrets more vulnerable to COVID-19 than dogs

A recent Chinese study published on the preprint server BioRxiv finds that cats and ferrets appear to be extremely vulnerable to the virus, but dogs, pigs, and poultry do not seem to contract it. As preprints, papers are not yet peer-reviewed, undergoing only basic scientific screening.

12 Apr 2020

Research shows entire brain responds to the gut through neuronal connections

You know that feeling in your gut? We think of it as an innate intuition that sparks deep in the belly and helps guide our actions, if we let it. It's also a metaphor for what scientists call the "gut-brain axis," a biological reality in which the gut and its microbial inhabitants send signals to the brain, and vice versa.

2 Apr 2020

How (easily) does the novel coronavirus spread?

Viruses are tiny bundles of DNA or RNA which have the ability to infect host cells, hijack the machinery of the host cell and then replicate. Once the host cell’s resources are exhausted, the viral particles are released to infect other cells. In this way, the viruses ensure their survival, often at the expense of the host.

1 Apr 2020

Small Intestine News and Research

Fecal transplants could be used as treatment for non-alcoholic fatty liver disease

New insights into how parenteral oil emulsions prevent liver disease in preterm babies

How COVID-19 affects the nervous system

How susceptible are domestic animals to SARS-CoV-2?

Changes in gut mucus are linked to brain disorders

Fibroblasts of different pancreatic diseases exhibit distinct properties, study reveals

Potential for COVID-19 transmission from human eye

Study: Diarrhea-causing bacteria provoke host's response to increase infectivity

Study finds bowel abnormalities in patients with COVID-19

Predicting the dose for repurposing nitazoxanide in COVID-19

Study explores the growth rate effect of gut bacteria on break down of dietary fibers

Research offers clues to how SARS-CoV-2 gets into respiratory tissue and exploits our defenses

Study shows how interactions between microbiome and the immune system contribute to liver disease

New study raises red flags about strategy to block cancer drug resistance

New therapeutic approach for preserving inflammation-free phases of Crohn's disease

Alzheimer's patients may need modified dosing regimens for selected drugs

Bacterial metabolism of bile acids boosts generation of immune cells, study shows

Cats, ferrets more vulnerable to COVID-19 than dogs

Research shows entire brain responds to the gut through neuronal connections

How (easily) does the novel coronavirus spread?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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