Smallpox News and Research

RSS

Smallpox is a highly contagious disease caused by the variola virus, a member of the Orthopox virus family. It is one of the most devastating diseases known to humanity, with a mortality rate as high as 30%. In 1967, the World Health Organization embarked upon an intensified vaccination campaign to eliminate smallpox, which culminated in the successful eradication of the disease globally by 1980.

By the mid-1980s, there were only two known repositories of variola virus: the Institute of Virus Preparations in Russia, and the US CDC. The events in the US in September and October 2001 highlighted the risk that the variola virus might be used as an agent of bioterrorism. Governments around the world are taking precautionary measures to be ready to deal with a potential smallpox outbreak.

Vaccines delivered via skin may offer better protection against respiratory diseases

Among infectious diseases that have caused pandemics and epidemics, smallpox stands out as a success story. Smallpox vaccination led to the disease's eradication in the twentieth century.

27 Jan 2021

Modified Vaccinia Ankara model vaccine prevents COVID-19 in transgenic mice study

A new study shows the effectiveness of a novel recombinant vaccinia virus that expresses modified SARS-CoV-2 spike antigen, in preventing the replication of the virus in the respiratory tract of transgenic mice, and to prevent lethal disease.

6 Jan 2021

Pandemic backlash jeopardizes public health powers, leaders

A series examining how the U.S. public health front lines have been left understaffed and ill-prepared to save us from the coronavirus pandemic.

15 Dec 2020

Oxford University podcast's third season to take listeners on a journey through historical pandemics

The University of Oxford's CASE Gold Award winning podcast, Futuremakers, will return for its third season at the end of October.

30 Nov 2020

Readers and tweeters shed light on vaccine trials and bias in health care

In the piece about the AstraZeneca vaccine trial subject who suffered severe spinal cord inflammation, that person was repeatedly referred to as a "patient" ("NIH 'Very Concerned' About Serious Side Effect in Coronavirus Vaccine Trial," Sept. 14).

28 Oct 2020

Qatar worker communities may have attained herd immunity against SARS-CoV-2

Now, a recent study published on the preprint server medRxiv* in September 2020 shows the achievement of herd immunity for SARS-CoV-2 infection by at least some expatriate worker communities in Qatar.

29 Sep 2020

Corralling the facts on herd immunity

For a term that's at least 100 years old, "herd immunity" has gained new life in 2020.

29 Sep 2020

New review explores the role of antibodies and T-cells towards an effective COVID vaccine

More than 100 companies have rushed into vaccine development against COVID-19 as the U.S. government pushes for a vaccine rollout at "warp speed" -- possibly by the end of the year -- but the bar set for an effective, long-lasting vaccine is far too low and may prove dangerous, according to Marc Hellerstein of the University of California, Berkeley.

11 Sep 2020

New book gives overview of viruses and how they emerge to cause pandemics

Since the novel coronavirus SARS-Cov-2 emerged late last year, it has been virtually impossible to consume any news without encountering stories about the virus and how it spreads, potential treatments, and the development of new vaccines.

11 Sep 2020

With schools starting online, vaccinations head for recess

As co-director of school-based health centers at Bassett Healthcare Network, the pediatrician oversees about 21 school-based health clinics across the region — a poor, rural area known for manufacturing and crippled by the opioid epidemic.

8 Sep 2020

Trust, fear and solidarity will determine the success of a COVID vaccine

Thousands of letters stuffed with money flooded Jonas Salk's mailbox the week after his polio vaccine was declared safe and effective in 1955. Everybody wanted his vaccine.

17 Aug 2020

Conspiracy theories aside, here’s what contact tracers really do

In the midst of the COVID-19 epidemic, contact tracing is downright buzzy, and not always in a good way.

15 Jul 2020

Coronavirus study shows herd immunity is infeasible

Herd immunity has been one of the key topics amid the coronavirus pandemic. Previous reports show that when a large proportion of the population gets immune to the novel coronavirus, through vaccination, herd immunity can be achieved.

7 Jul 2020

Research suggests protective effect of influenza vaccine against COVID-19 severity and mortality

A new study involving over 92,000 patients with COVID-19 in Brazil shows that the odds of severe disease, ventilatory support requirement, and death are reduced with a recent trivalent flu vaccine. This seems to indicate that these vaccines should be used as widely as possible to reduce the risk of severe COVID-19, especially among high-risk groups. The study is published on the preprint server medRxiv* in June 2020.

5 Jul 2020

Integration of diverse set of species and environments can enhance biomedical research cycle

In an article published today in Science, a multidisciplinary research team from more than 10 universities and research institutes outlines how integrating a more diverse set of species and environments could enhance the biomedical research cycle.

3 Jul 2020

Modified Vaccinia Ankara-based vaccine candidate for SARS-CoV-2

Now, a new study by researchers at Emory University, the University of Texas Medical Branch and the Ragon Institute and published on the preprint server bioRxiv in June 2020 reports the development of a promising new vaccine candidate that may rapidly and effectively induce the production of neutralizing antibodies against the spike protein of the virus.

30 Jun 2020