Spike Protein News and Research

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Discovery of novel antibody that targets shared epitope on SARS-CoV-2 variants

Researchers assessed the antibody responses elicited by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and defined the epitopes shared by them.

28 Apr 2022

Does re-freezing COVID-19 mRNA vaccines affect immunogenicity?

A new study published in the journal Vaccines evaluated if re-freezing coronavirus disease 2019 (COVID-19) mRNA vaccine vials preserved the immunogenicity.

27 Apr 2022

How severity and progression of COVID-19 affect cytokine profiles in pregnant women

The current study deals with the results of serum cytokine analysis in a small group of pregnant women with and without COVID-19 in the third trimester in a single New York City hospital.

27 Apr 2022

Bebtelovimab potently neutralizes all SARS-CoV-2 variants of concern

The current study, escribes a new mAb LY-CoV1404 (bebtelovimab) from Eli Lilly, with high neutralization potency with a broad spectrum of activity across all current variants.

27 Apr 2022

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

In a study published in Cells, researchers have been investigating the effects of this extract for use against COVID-19.

27 Apr 2022

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Scientists from Germany have recently identified Hypericum perforatum, a widespread herbal plant known as St. John's wort, as a potential antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is published in the journal Pharmaceuticals.

27 Apr 2022

Research highlights importance of booster vaccine doses to protect against all Omicron variants

In a recent study published in the Cell Host and Microbe journal, researchers examined the neutralization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1, BA.1.1, and BA.2 sublineages.

27 Apr 2022

Antibodies against the original strain of SARS-CoV-2 may not work as well with omicron

If you're wondering why after two vaccination doses and a booster shot, you still got sick from the omicron strain of the virus that causes COVID-19, one possible answer may have been found in a recent study by researchers at Johns Hopkins Medicine and the National Institute of Allergy and Infectious Diseases at the National Institutes of Health.

26 Apr 2022

mRNA booster vaccination found to protect aged mice against the Omicron variant of SARS-CoV-2

A new study examined the protective effect of the mRNA booster vaccine against the SARS-CoV-2 Omicron variant in 21-month-old mice.

26 Apr 2022

Evidence of increased intrinsic cleavability of SARS-CoV-2 Omicron spike protein by host cell furin

Researchers conducted an in vitro analysis to assess the host cell furin-mediated cleavability of the spike protein of the SARS-CoV-2 Omicron (B.1.529) variant.

26 Apr 2022

Canine COVID-19 vaccine could prevent reverse transmission of SARS-CoV-2

The new study, published in the journal Vaccines, reports on an attempt to use the SARS-CoV-2 spike subunit protein to elicit an immune reaction.

26 Apr 2022

A novel mouse model to test SARS-CoV-2 viral infection

In a recent study posted to the Research Square* preprint server, researchers developed a novel mouse model for testing infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

26 Apr 2022

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

A COVID-19 vaccine developed at the University of Washington School of Medicine has proven safe and effective in late-stage clinical testing.

25 Apr 2022

The challenges of Omicron

A new review published in sums up the position of Omicron as a potential threat to human health, especially in the context of controlling this pandemic.

25 Apr 2022

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, the researchers investigated the impact of Bacillus Calmette-Guérin (BCG) vaccine-induced antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein.

25 Apr 2022

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

A recent review paper, published in the MDPI’s specialized journal COVID, highlights key features of the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and examines the potential and roadblocks in using renewable marine resources in the fight against the coronavirus disease 2019 (COVID-19).

24 Apr 2022

Spike Protein News and Research

Discovery of novel antibody that targets shared epitope on SARS-CoV-2 variants

Does re-freezing COVID-19 mRNA vaccines affect immunogenicity?

How severity and progression of COVID-19 affect cytokine profiles in pregnant women

Bebtelovimab potently neutralizes all SARS-CoV-2 variants of concern

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Research highlights importance of booster vaccine doses to protect against all Omicron variants

Antibodies against the original strain of SARS-CoV-2 may not work as well with omicron

mRNA booster vaccination found to protect aged mice against the Omicron variant of SARS-CoV-2

Evidence of increased intrinsic cleavability of SARS-CoV-2 Omicron spike protein by host cell furin

Canine COVID-19 vaccine could prevent reverse transmission of SARS-CoV-2

A novel mouse model to test SARS-CoV-2 viral infection

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

The challenges of Omicron

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

Quercetin and other plant flavonols show anti-SARS-CoV-2 activity

Antibody escape in SARS-CoV-2 Omicron spike protein

Study demonstrates that a low-dose, bivalent, unmodified mRNA vaccine against SARS-CoV-2 is highly efficacious

SARS-CoV-2 spike protein disrupts lipid metabolism resulting in liver, heart & kidney damage

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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