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Study suggests seropositive individuals produce anti-SARS-CoV-2 antibodies with improved potency and breadth

Researchers isolated single cells among individuals with and without prior infection with the SARS-CoV-2 vaccinated with BNT162b2 mRNA vaccine and compared the nature of the neutralizing antibody response against the original Wuhan virus and the subsequent variants.

25 Oct 2021

SARS-CoV-2 Delta variant transmitted by fully vaccinated individuals in Provincetown, Massachusetts

A new study, posted to the medRxiv* preprint server, describes the genomic epidemiology of this outbreak. It provides a deeper understanding of viral transmission from and between fully vaccinated individuals.

25 Oct 2021

Targeting SARS-CoV-2 with Chaga mushroom – a natural antiviral compound

A new study examines the potential binding interaction of the beneficial components of Chaga mushroom with that of the SARS-CoV-2 RBD.

24 Oct 2021

A comparison between Pfizer/BioNTech's and Sinopharm's SARS-CoV-2 vaccines

Researchers compare antibody titers elicited the Pfizer‐BioNTech mRNA and the classic inactivated virus Sinopharm vaccines.

24 Oct 2021

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Researchers discuss mutations in the NTD of the spike protein, which contains an antigenic “supersite” and is the target for nAbs.

24 Oct 2021

Mu and C.1.2 variant spike proteins partially resistant to neutralization by vaccine-elicited antibodies

A team of researchers measured the infectivity of SARS-CoV-2 variants C.1.2, Mu, and Delta+501S spike proteins and determined the susceptibility to neutralizing antibodies.

22 Oct 2021

Immunogenicity and efficacy of adjuvanted SARS-CoV-2 beta variant subunit booster in rhesus macaques

Scientists studied the efficacy of an intranasal booster composed of beta variant-spike protein S1 with IL-15 and TLR agonists in macaques that were previously immunized.

22 Oct 2021

Replication of SARS-CoV-2 variants in different cell and organ models

In this study, the replication of B.1.1.7 viruses was analyzed in different cell and organ models and dwarf hamsters.

22 Oct 2021

Development of a safe and effective COVID-19 nanoparticle vaccine

Researchers from ReVacc scientific have attempted to demonstrate the effectiveness of a new vaccine, REVC-128, two weeks post-administration.

22 Oct 2021

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Researchers from Stanford University have been attempting to create a hydrogel-based vaccine delivery system that could improve the immune response's strength and duration.

22 Oct 2021

Boosting nonhuman primates with Moderna vaccine increases neutralizing antibody responses

Boosting nonhuman primates with the Moderna vaccine (mRNA-1273) six months after their primary vaccine series increased neutralizing activity against viral variants of concern, a new study shows.

22 Oct 2021

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Amidst growing concerns on the use and potential benefits of convalescent plasma therapy, a research group in the United States has identified three human antibodies (Abs) that, when combined, demonstrate both robust viral suppressive properties against all tested severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Variants of Concern (VoC) in vitro and profound antiviral efficacy in vivo.

22 Oct 2021

Spike Protein News and Research

Study suggests seropositive individuals produce anti-SARS-CoV-2 antibodies with improved potency and breadth

SARS-CoV-2 Delta variant transmitted by fully vaccinated individuals in Provincetown, Massachusetts

Targeting SARS-CoV-2 with Chaga mushroom – a natural antiviral compound

A comparison between Pfizer/BioNTech's and Sinopharm's SARS-CoV-2 vaccines

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Mu and C.1.2 variant spike proteins partially resistant to neutralization by vaccine-elicited antibodies

Immunogenicity and efficacy of adjuvanted SARS-CoV-2 beta variant subunit booster in rhesus macaques

Replication of SARS-CoV-2 variants in different cell and organ models

Development of a safe and effective COVID-19 nanoparticle vaccine

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Boosting nonhuman primates with Moderna vaccine increases neutralizing antibody responses

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Broadly protective vaccines against coronaviruses needed to protect against future outbreaks

New research on phagocytosis and SARS-CoV-2's spike protein

Scientists search for cause of mysterious covid-related inflammation in children

Suggested mechanism of SARS-CoV-2 infection inhibition by Mitoxantrone

Long-term predictions of immunity after two doses of mRNA vaccine

BNT162b2 mRNA COVID-19 vaccine-induced antibodies wane over six month period

Research may provide clues to how viral infections contribute to neurodegeneration

Phase 2 trial shows COVID-19 recombinant protein vaccine elicits promising immunogenicity responses

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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