Spike Protein News and Research

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Scientists develop an extremely potent siRNA with broad activity against SARS-CoVs

Researchers in Germany have developed a promising approach to suppressing the viral replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

12 Oct 2021

Rapid measurement of SARS-CoV-2 spike T-cells

Researchers measure SARS-CoV-2 T-cell responses in individuals vaccinated or in those who developed immunity from a prior natural infection.

12 Oct 2021

A survey on computational methods in discovering protein inhibitors of SARS-CoV-2

Researchers review diverse computational methods for drug/inhibitor design and enzymes as potential targets for inhibitors to treat coronaviruses diseases.

12 Oct 2021

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

Recently, scientists have developed a bacterial two-hybrid (B2H) system to study the PPIs of SARS-CoV-2 in a heterologous non-eukaryotic system. This study is available on the bioRxiv* preprint server. Put simply, the B2H system could be used to analyze the SARS-CoV-2 proteome.

11 Oct 2021

New compound can prevent SARS-CoV-2 and related coronaviruses from entering cells

Scientists at Washington University School of Medicine in St. Louis have developed a compound that prevents SARS-CoV-2 and related coronaviruses from entering cells.

11 Oct 2021

Analysis of SARS-CoV-2 Delta variant transmissibility across New England, USA

A recent study compares the transmissibility of the SARS-CoV-2 Alpha and Delta variants in six states across New England in the United States

11 Oct 2021

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

A recent study demonstrates that antibodies generated in response to mRNA-based COVID-19 vaccination target more epitopes across the spike protein.

11 Oct 2021

The role of inhibiting palmitoylation of the SARS-CoV-2 spike protein on viral infectivity

It is demonstrated that palmitoylation of the first five cysteine residues of the C-terminal domain of the SARS-CoV-2 spike protein facilitates cell entry and the formation of syncytia.

11 Oct 2021

Delta variant exhibits immune evasion, enhanced cell entry, and augmented syncytium formation

Researchers addressed the question of using reporter particles pseudotyped with the S protein of SARS-CoV-2, which are suitable tools to examine SARS-CoV-2 neutralization antibodies.

11 Oct 2021

Vaccine-induced memory B cells can recognize SARS-CoV-2 variants

Researchers have been investigating the effect that memory B cells produced in individuals who have received an mRNA vaccine have against SARS-CoV-2 variants.

11 Oct 2021

Sero-epidemiological insights into pathways to COVID-19 immunity

A new study posted to the medRxiv* server attempts to utilize serology as a tool to identify disparities in infection rates and vaccination coverage.

10 Oct 2021

The neurological effects of COVID-19

What is the relationship between COVID-19 and the brain? A new review published in Tropical Biomedicine summarizes the key findings on how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe COVID-19 infection, disrupts brain activity and produces a range of long-term neurological disorders.

10 Oct 2021

Spike Protein News and Research

Scientists develop an extremely potent siRNA with broad activity against SARS-CoVs

Rapid measurement of SARS-CoV-2 spike T-cells

A survey on computational methods in discovering protein inhibitors of SARS-CoV-2

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

New compound can prevent SARS-CoV-2 and related coronaviruses from entering cells

Analysis of SARS-CoV-2 Delta variant transmissibility across New England, USA

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

The role of inhibiting palmitoylation of the SARS-CoV-2 spike protein on viral infectivity

Delta variant exhibits immune evasion, enhanced cell entry, and augmented syncytium formation

Vaccine-induced memory B cells can recognize SARS-CoV-2 variants

Sero-epidemiological insights into pathways to COVID-19 immunity

The neurological effects of COVID-19

Accumulation of SARS-CoV-2 mutations reduces sensitivity to neutralizing antibodies

Lipids, COVID-19, and host immunity

Powerful neutralizing antibody against SARS-CoV-2 variants of concern

Study supports efficacy and safety of lung-selective nanotherapy against SARS-CoV-2 infection

Oral and intranasal COVID-19 vaccines show promising results in hamster model

mRNA vaccination associated with decreased risk of COVID-19 infection and hospitalization in U.S. veterans

Assay to assess and quantify presence of RBD-directed antibodies against SARS-CoV-2 following vaccination

Adapting biological research and development to COVID-19

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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