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Next-generation vaccine strategies to combat current and emerging SARS-CoV-2 variants

Announcing a new article publication for Zoonoses journal. Vaccines are among the most effective medical countermeasures against infectious diseases.

19 Apr 2023

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

The newly developed DCFHP-alum COVID-19 vaccine candidate is affordable and effective for mass vaccination.

18 Apr 2023

Cocktail of IgG3 antibodies could have a potent clinical effect against SARS-CoV-2

Is it possible to improve the antibodies that the body produces to fight SARS-CoV2? In a study led by researchers from Lund University in Sweden, this was investigated by redesigning antibodies and combining them against the virus.

18 Apr 2023

Scientists discover a protein domain that could lead to new COVID-19 treatments

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

18 Apr 2023

Antibody response to SARS-CoV-2 is stronger and more durable in infants and young children

Researchers evaluated humoral responses to severe acute respiratory syndrome coronavirus 2 in infants.

15 Apr 2023

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

The current COVID-19 vaccines are designed to trigger an antibody response to the SARS-CoV-2 spike protein, which is vulnerable to mutations that could make the vaccine less effective over time.

13 Apr 2023

The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity

Reported the identification of a panel of vaccinee-derived antibodies with broad-spectrum neutralization activity.

12 Apr 2023

VUMC-led trial demonstrates the inefficacy of two investigational drugs for treating severe COVID-19

Despite the success of vaccines for preventing COVID-19, and of drugs for treating the disease, outcomes for severely ill patients admitted to the hospital remains poor.

11 Apr 2023

Scientists isolate two antibodies that neutralize all current SARS-CoV-2 variants of concern

Researchers found antibodies that neutralize all current SARS-CoV-2 variants.

11 Apr 2023

Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

Researchers assess the efficacy of the human surfactant protein A against SARS-CoV-2 infectivity.

10 Apr 2023

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers report on the benefits of consuming dietary phenols and their relationship with the intestinal microbiome.

10 Apr 2023

Impact of maternal COVID-19 on neonatal brain development

Researchers described two coronavirus disease 2019 (COVID-19) -infected neonate cases.

10 Apr 2023

COVID mRNA vaccines fall short in eliciting lung resident memory T cells compared to natural infection

Pieren, D. K. J., Kuguel, S. G., Rosado, J., Robles, A. G., Rey-Cano, J., Mancebo, C., Esperalba, J., Falcó, V., Buzón, M. J., & Genescà, M. (2023). Limited induction of polyfunctional lung-resident memory T cells against SARS-CoV-2 by mRNA vaccination compared to infection. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-37559-w, https://www.nature.com/articles/s41467-023-37559-w

10 Apr 2023

Newly discovered antibody appears to block infection by all dominant variants of SARS-CoV-2 virus

A team led by researchers at Weill Cornell Medicine, the University of Wisconsin-Madison; Scripps Research and the University of Chicago has identified an antibody that appears to block infection by all dominant variants of the virus that causes COVID-19, including Omicron, the most recent.

7 Apr 2023

Spike Protein News and Research

Next-generation vaccine strategies to combat current and emerging SARS-CoV-2 variants

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

Cocktail of IgG3 antibodies could have a potent clinical effect against SARS-CoV-2

Scientists discover a protein domain that could lead to new COVID-19 treatments

Antibody response to SARS-CoV-2 is stronger and more durable in infants and young children

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity

VUMC-led trial demonstrates the inefficacy of two investigational drugs for treating severe COVID-19

Scientists isolate two antibodies that neutralize all current SARS-CoV-2 variants of concern

Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Impact of maternal COVID-19 on neonatal brain development

COVID mRNA vaccines fall short in eliciting lung resident memory T cells compared to natural infection

Newly discovered antibody appears to block infection by all dominant variants of SARS-CoV-2 virus

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

Study explores the species-specific use of ACE2 receptors by human and animal coronaviruses

Study suggests psychosocial factors, not acute infections, contribute to long-COVID in young adults

Live attenuated nasal vaccine elicits superior immunity to SARS-CoV-2 variants in hamsters

Spike protein could be responsible for memory loss in post-COVID-19 syndrome

Red blood cell hitch-hiking facilitates SARS-CoV-2 multi-organ spread

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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