Spondylitis News and Research

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New insights into the exacerbation of psoriasis through specific genetic defects

The inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model.

27 Mar 2024

Risk factors for serious inflammatory conditions in IBD patients identified

Investigators at Cedars-Sinai have identified risk factors that make inflammatory bowel disease (IBD) patients susceptible to developing serious conditions in other parts of their bodies.

20 Mar 2024

Tryptophan digestion by gut microbiome spurs arthritis inflammation

A University of Colorado Department of Medicine faculty member says she and her colleagues have identified the means in which bacteria in the digestive system can break down tryptophan in the diet into an inflammatory chemical that primes the immune system towards arthritis.

7 Mar 2024

Study sheds light on early life risk factors for ankylosing spondylitis

Having older siblings and childhood tonsil removal are linked to a heightened risk of ankylosing spondylitis, a type of chronic inflammatory arthritis, finds a large study published in the open access journal RMD Open.

16 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

COVID-19 heightens risk of autoimmune disorders

SARS-CoV-2 infection may elevate risk for certain autoimmune disorders, suggests study. Regular post-COVID monitoring needed to detect and manage potential autoimmune consequences.

9 Oct 2023

Is there an association between psoriasis onset and risk of autoimmune disease?

Researchers evaluated new-onset autoimmune disease risk among individuals with new-onset psoriatic illness.

9 Oct 2023

High BMI linked to increased risk of 5 rheumatic diseases

A new study by Uppsala University shows that a higher body mass index (BMI) increases the risk of five different rheumatic diseases: rheumatism, osteoarthritis, gout, psoriatic arthritis and inflammatory spondylitis. The researchers also noted that BMI was a stronger risk factor for women compared to men in terms of gout and psoriatic arthritis. The study will be presented in the journal Arthritis & Rheumatology.

26 Jun 2023

How do viral infections cause autoimmune diseases?

Researchers describe the pathological mechanisms of virus-induced autoimmune diseases.

28 Mar 2023

Investigating the impact of COVID-19 vaccinations in immunocompromised adult patients

In a recent study posted to the medRxiv* preprint server, researchers assessed the impact of third and fourth coronavirus disease 2019 (COVID-19) vaccination doses on immunity against COVID-19 among immunocompromised adult patients.

9 Mar 2023

Self-directed autoantibodies against certain chemokines may protect against long-COVID

A recent study published in the journal Nature Immunology discovered autoantibodies against chemokines following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

8 Mar 2023

Study shows how arthritis affects people's working lives

The typical person living with arthritis in the UK is 20% less likely to be in work than their equivalent without the condition, new research shows.

30 Jan 2023

Combination treatment does not slow radiographic spinal progression in radiographic axSpA patients

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, showed that combining a nonsteroidal anti-inflammatory drug and TNF inhibitor did not significantly slow radiographic spinal progression in radiographic axial spondyloarthritis patients.

8 Nov 2022

Study estimates the quality of care for patients with long-term health conditions

The number of new diagnoses of rheumatoid arthritis fell by 20% in the first year of the COVID-19 pandemic, new research suggests.

4 Nov 2022

New data analysis approach could help uncover the genetic basis of many diseases

In the era of Big Data, obtaining a huge amount of information is the easy part; knowing what to do with it is another story entirely.

9 Sep 2022

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

With this approval, RINVOQ® is the first and only Janus Kinase inhibitor approved to treat patients across the spectrum of axial spondyloarthritis (nr-axSpA and ankylosing spondylitis) in the EU.

From AbbVie 29 Jul 2022

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

AbbVie today announced the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) recommended the approval of upadacitinib (RINVOQ® 15 mg, once daily) for the treatment of active non-radiographic axial spondyloarthritis (nr‑axSpA) in adult patients with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI), who have responded inadequately to nonsteroidal anti-inflammatory drugs (NSAIDs).*

27 Jun 2022

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

27 Jun 2022

Risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and those on immune-modifying therapies

Researchers assessed the risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and those on immunomodulatory therapies.

13 Jun 2022

Exploring the effectiveness of various treatments in people with axial spondyloarthritis

axSpA is a chronic inflammatory rheumatic disease that mainly affects the spine and sacroiliac joints. It can cause significant pain and disability.

3 Jun 2022

Spondylitis News and Research

New insights into the exacerbation of psoriasis through specific genetic defects

Risk factors for serious inflammatory conditions in IBD patients identified

Tryptophan digestion by gut microbiome spurs arthritis inflammation

Study sheds light on early life risk factors for ankylosing spondylitis

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

COVID-19 heightens risk of autoimmune disorders

Is there an association between psoriasis onset and risk of autoimmune disease?

High BMI linked to increased risk of 5 rheumatic diseases

How do viral infections cause autoimmune diseases?

Investigating the impact of COVID-19 vaccinations in immunocompromised adult patients

Self-directed autoantibodies against certain chemokines may protect against long-COVID

Study shows how arthritis affects people's working lives

Combination treatment does not slow radiographic spinal progression in radiographic axSpA patients

Study estimates the quality of care for patients with long-term health conditions

New data analysis approach could help uncover the genetic basis of many diseases

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

Risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and those on immune-modifying therapies

Exploring the effectiveness of various treatments in people with axial spondyloarthritis

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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