Statin News and Research

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Statins are drugs used to lower cholesterol. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can stick to the walls of your arteries, narrowing or even blocking them.

Aching back? cholesterol drug Lovastatin might help

Back pain, a hallmark of degenerative disc disease, sends millions of people to their doctor. In fact, more than 80 percent of patients who undergo spine surgery do so because of disc degeneration.

22 Feb 2009

VAP cholesterol test helps find link between a rare gene mutation and heart protection

Using the VAP Cholesterol Test from Atherotech, Inc., University of Maryland researchers have found an association between a rare gene mutation and heart protection.

17 Feb 2009

Continuation of statin treatment associated with lower risk of death

Patients with high cholesterol levels who continually take statins appear to have a lower risk of death over four to five years, regardless of whether they already have diagnosed heart disease, according to a report in the February 9 issue of Archives of Internal Medicine , one of the JAMA/Archives journals.

9 Feb 2009

Atorvastatin and lovastatin found to be ineffective for breast cancer prevention

Laboratory work in animals showed limited activity when statins were given to prevent breast cancer, according to a report in the February issue of Cancer Prevention Research , a journal of the American Association for Cancer Research.

8 Feb 2009

Statins may treat cerebral cavernous malformation

In a finding that could save thousands of lives a year, University of Utah School of Medicine researchers have shown that a blood vessel disorder leading to unpredictable, sometimes fatal, hemorrhagic strokes, seizures, paralysis or other problems is treatable with the same statin drugs that millions of people take to control high cholesterol.

27 Jan 2009

Impaired kidney function raises risk of heart problems in the elderly

A study published next week in the open access journal PLoS Medicine suggests that elderly people with damaged kidneys are at greater risk of cardiovascular disease, such as heart failure and stroke, and other causes of mortality.

21 Jan 2009

New diagnostic tool to measure blood flow could prevent needless stents

Doctors may be implanting too many artery-opening stents and could improve patient outcomes - and ultimately save lives - if they did more in-depth measurements of blood flow in the vessels to the heart.

15 Jan 2009

Numerical analysis estimates numbers of older US adults who may benefit from statin therapy

Researchers estimate more than 11 million older Americans may be newly eligible for statin therapy if findings from a recently published large clinical trial are adopted into clinical practice guidelines, according to a new analysis of the trial data.

13 Jan 2009

Thumbs down by experts on plans to make certain meds OTC

Government plans to make certain prescription-only drugs for common problems available over the counter have overwhelmingly been given the thumbs down by healthcare professionals, reveals a survey of readers of the influential Drug and Therapeutics Bulletin ( DTB ).

13 Jan 2009

An explanation of how statins cause low rates of muscle symptoms

In the January 2009 issue of the American Journal of Medicine , Florida Atlantic University researcher Charles H. Hennekens, M.D., the first Sir Richard Doll Research Professor in the Charles E. Schmidt College of Biomedical Science and a renowned expert who has revealed numerous causal, therapeutic and preventive factors in the treatment and prevention of cardiovascular disease (CVD), most notably low-dose aspirin, explains why statins cause low rates of muscle symptoms.

9 Jan 2009

Framingham and National Cholesterol Education Program tools do not accurately predict coronary heart disease

The Framingham and National Cholesterol Education Program tools, NCEP, do not accurately predict coronary heart disease, according to a study performed at the Yale University School of Medicine in New Haven, CT.

6 Jan 2009

Low-glycemic foods better for glycemic control than high-fiber

Persons with type 2 diabetes who had a diet high in low-glycemic foods such as nuts, beans and lentils had greater improvement in glycemic control and risk factors for coronary heart disease than persons on a diet with an emphasis on high-cereal fiber, according to a study in the December 17 issue of JAMA, the Journal of the American Medical Association.

16 Dec 2008

Single letter in the human genome points to risk for high cholesterol

Write out every letter in the human genome, one A, C, T or G per millimeter, and the text would be 1,800 miles long, roughly the distance from New York to Colorado.

16 Dec 2008

Pregnant women warned not to use statins

Pregnant women or those hoping to start or extend a family should avoid using the cholesterol-lowering drugs statins, say scientists.

From The University of Manchester 10 Dec 2008

Statins do not interfere with Rituximab treatment for lymphomas

Statins, drugs widely prescribed to lower cholesterol, do not interfere with a commonly used medication to treat lymphomas, according to a Mayo Clinic study presented at the 50th Annual Meeting of the American Society of Hematology in San Francisco.

8 Dec 2008

Discovery of six novel genetic variants associated with lipid levels

A new study presages a real aim of genetics: to look at whole populations to in order determine the significance of individual genetic variants for individual health.

8 Dec 2008

Discovery of 11 new gene sites that influence cholesterol or triglyceride levels

An international research team has identified 11 novel locations in the human genome where common variations appear to influence cholesterol or triglyceride levels, bringing the total number of lipid-associated genes to 30.

8 Dec 2008

Scientists find 12 new genes with potential as drug targets

Scientists have identified 12 new genes that are somewhat strange bedfellows: Some link gallstones and blood cholesterol levels, others link melatonin and sleep patterns to small increases in glucose levels and larger jumps in the risk of diabetes.

8 Dec 2008

Study finds six genetic variants associated with 'bad' cholesterol

A new study presages a real aim of genetics: to look at whole populations to in order determine the significance of individual genetic variants for individual health. The research team, whose work is published in Nature Genetics, find six novel genetic variants that are associated with lipid levels, a common indicator of heart or artery disease.

7 Dec 2008