Statin News and Research

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Statins are drugs used to lower cholesterol. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can stick to the walls of your arteries, narrowing or even blocking them.

Statins lower C-reactive protein (CRP), a major new risk factor for heart disease marked by inflammation

For years, doctors have believed that statin therapy lowers the risk of heart disease solely by lowering levels of cholesterol.

9 Jan 2005

New guidelines for treating diabetes

Every year, the American Diabetes Association (ADA) issues Clinical Practice Recommendations, a series of updated recommendations to help health care providers treat people with diabetes using the most current research available.

7 Jan 2005

Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein

Aggressive therapy with statins -- drugs that inhibit cholesterol synthesis -- works better than moderate statin therapy in reducing fats and proteins in the blood that have been linked to atherosclerosis, a new multi-center study concludes. Statins’ effects on both complex compounds appear beneficial in cutting patients’ cardiovascular risks.

6 Jan 2005

The rise in over the counter drugs, why?

Switching of prescription drugs to over the counter availability is increasingly common, but what are the motives behind this trend, ask US researchers in this week's BMJ?

3 Jan 2005

Excellent news for the many people who suffer from high blood pressure

An international trial comparing blood-pressure lowering treatments has been stopped early due to the significantly better performance of one of the treatments in the trial.

8 Dec 2004

Noninvasive test of blood flow response may reveal early coronary disease

Chest pain patients who have abnormal coronary blood vessel function also have less responsive blood vessels in their fingertips, suggesting that a type of fingertip probe could become a useful screening tool, according to a new study in the Dec. 7, 2004 issue of the Journal of the American College of Cardiology.

8 Dec 2004

Life expectancy at 65 is now 81.6 years for men and 84.5 for women

The nation’s medicine cabinets are more crowded than ever, with almost half of all people taking at least one prescription medicine and one in six taking three or more medications, according to the U.S. Department of Health and Human Services’ annual check-up on Americans’ health.

4 Dec 2004

Information about serious adverse effects of cerivastatin were known within months after drug launched

A review of the published literature and of internal company documents from the manufacturer of cerivastatin, a cholesterol lowering drug removed from the market in 2001, suggests that information about serious adverse effects of this medication was known to the company within months after this drug was launched

23 Nov 2004

Patients taking the lipid-lowering medications have a relatively low risk of developing rhabdomyolysis

Patients taking the lipid-lowering medications atorvastatin, pravastatin, and simvastatin to reduce cholesterol levels, have a relatively low risk of developing rhabdomyolysis, (a disorder that causes the breakdown of muscle), according to a new study in the December 1 issue of JAMA.

23 Nov 2004

AstraZeneca reconfirms the safety of Crestor

In the case of Crestor (rosuvastatin calcium), the application for approval was the most extensive ever for a statin involving more than 12,000 patients, and was unanimously recommended for approval by the FDA's advisory board in July of 2003.

20 Nov 2004

Keeping fit lowers C-Reactive protein in people with metabolic syndrome

In people with signs of metabolic syndrome, including high blood pressure, high triglycerides, high cholesterol, elevated blood glucose and obesity, physical activity appears to reduce a marker for inflammation which has been linked to heart disease

16 Nov 2004

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

The cholesterol-lowering drug atorvastatin slowed down mental decline and improved depressive symptoms in people with Alzheimer’s disease, according to a small pilot study reported at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Generic statin drugs shown to produce similar or better results than expensive brand-name drugs

Researchers from Kaiser Permanente's Northern California region are presenting a study at this week's American Heart Association Scientific Sessions showing that patients who use a generic statin drug rather than its brand-name equivalent fared as well as- sometimes better than-patients on the more expensive drug.

8 Nov 2004

High-dose statin therapy for aggressive cholesterol-lowering outperforms typical care

Patients treated with high doses of atorvastatin had about a one percent lower annual rate of heart attacks than similar patients receiving usual care, according to a new study in the Nov. 2, 2004 issue of the Journal of the American College of Cardiology.

2 Nov 2004

Do cholesterol-reducing drugs decrease the risk of heart attacks and strokes in diabetics?

International researchers will, for the first time, present findings from the landmark 4D trial about whether a cholesterol-reducing drug decreases the risk of heart attacks and strokes with type 2 diabetics on dialysis at the American Society of Nephrology’s 37th Annual Meeting and Scientific Exposition in St. Louis, Missouri.

1 Nov 2004

Scientists closer to understanding the potential effects of anti-cholesterol drugs on Alzheimer's disease

Scientists at Jefferson Medical College and the Farber Institute for Neurosciences at Thomas Jefferson University in Philadelphia have taken another step in understanding the potential effects of anti-cholesterol drugs on Alzheimer's disease.

25 Oct 2004

A new approach to controlling blood cholesterol levels may be a potential treatment for Alzheimer's disease

A new approach to controlling blood cholesterol levels that is already being investigated to prevent cardiovascular disease also may be a potential treatment for Alzheimer's disease.

13 Oct 2004

Study increases likelihood that MRI could be used as predictive technology to determine which patients should be placed on statin therapy for atherosclerosis

Using modified magnetic resonance imaging (MRI) techniques, researchers at Johns Hopkins have been able to detect the early benefits of a cholesterol-lowering medication much sooner than before.

11 Oct 2004

HHS enhances Medicare drug card program to help seniors

Health and Human Services Secretary Tommy G. Thompson today announced new measures to help seniors get the lowest price possible for their medicines by allowing them -- for the first time -- to compare prices for similar drugs used to treat common diseases such as high cholesterol or blood pressure.

15 Sep 2004

Missing link between inflammatory markers in the bloodstream and the increased risk of heart attack

The study of 386 Olmsted County, Minn., residents used transesophageal echocardiography (TEE) to obtain high-quality images of the lining of the aorta, the main artery through which the heart pumps blood to the body.

14 Sep 2004