Statin News and Research

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Statins are drugs used to lower cholesterol. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can stick to the walls of your arteries, narrowing or even blocking them.

Statin therapy is cost-effective for a wider range of individuals with vascular disease or diabetes than previously recognised

Current guidelines generally recommend the initiation of statin therapy when the estimated 10-year risk of a non-fatal heart attack or coronary death is at least 15-20%.

12 May 2005

Targeted Genetics announces new patent for Hyperlipidemia

Targeted Genetics Corporation announced today issuance of U.S. patent #6,887,463, entitled, "Methods and Compositions for Gene Therapy for the Treatment of Defects in Lipoprotein Metabolism."

11 May 2005

Drug lowers inflammatory markers associated with risk for heart attack

A preliminary study suggests that use of a drug that inhibits a specific protein in patients with certain genetic variants that increase their risk for heart attack reduced their levels of inflammatory markers associated with heart attack risk, according to a study in the May 11 issue of JAMA.

10 May 2005

Polypill improves survival rates for heart disease sufferers

A ‘polypill’ made up of a combination of drugs could extend the lives of thousands of patients with coronary heart disease, say researchers at The University of Nottingham.

10 May 2005

Drug combinations improve survival for patients with heart disease

Patients with coronary heart disease who take a combination of three specific drugs have a better chance of survival than those taking single drugs, finds a study in this week's BMJ.

5 May 2005

Fiber supplements may lower cardiovascular risk in type 2 diabetics

Fiber supplements lower "bad" low-density lipoprotein (LDL) cholesterol and increase "good" high-density lipoprotein (HDL) cholesterol in people with type 2 diabetes, according to a study presented at the American Heart Association's Sixth Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology.

1 May 2005

Research may re-define management of heart failure in diabetes

Control of oxidised copper levels in the body may be as important as lowering blood glucose levels in preventing cardiovascular complications in diabetes mellitus, according to New Zealand researchers.

28 Apr 2005

Antibiotics do not prevent heart attacks

Clinicians and researchers have found that more than three quarters of heart attack patients have been infected with chlamydia pneumoniae - a bacteria found in arteries of heart attack patients - and multiple studies have found this can double the risk of developing subsequent heart attacks.

27 Apr 2005

New statin study shows arrested progression of atherosclerosis

The first study to use cutting edge magnetic resonance imaging to examine the effect of a statin - rosuvastatin (Crestor) - on the fatty plaques in arteries, was presented yesterday at the 75th European Atherosclerosis Society Congress. ORION revealed that rosuvastatin has a beneficial effect on the size and composition of fatty plaques in arteries (specifically the carotid artery in the neck). Fatty plaques that are vulnerable to sudden rupture can cause heart attacks and strokes without warning.

25 Apr 2005

Statins help cut risk for advanced prostate cancer

In a 10-year study of more than 30,000 health professionals, researchers at Johns Hopkins and Harvard found that the longer men take cholesterol-lowering drugs such as statins, the far less likely they are to develop advanced prostate cancer.

19 Apr 2005

Statins used before or after strokes improve outcomes

New research into the use of statins before or after a stroke has shown that a patients recovery after an ischemic stroke can be improved.

12 Apr 2005

Swedish team find gene with link to major diseases

In an exciting new discovery, which could affect millions of people, scientists from the Karolinska Institute and the Centre for Molecular Medicine (CMM) in Stockholm, Sweden, have identified a gene which links autoimmune diseases with cardiovascular diseases.

12 Apr 2005

Hemodialysis causes antioxidant loss leading to long-term complications

An article published in Hemodialysis International discusses the role of oxidative stress (OS) in dialysis patients, an imbalance which can result in long-term health problems. Potential therapeutic options to restore balance in patients are also reviewed.

10 Apr 2005

First identified gene to link autoimmune diseases with cardiovascular diseases

A common gene variant has been identified as the risk factor behind a number of common diseases by research scientists at Karolinska Institutet and the Centre for Molecular Medicine (CMM), Stockholm, Sweden. Up to a quarter of the population could be affected.

10 Apr 2005

Role of oxidative stress (OS) in dialysis patients

7 Apr 2005

Almonds may help combat obesity, heart disease and diabetes

Three studies presented during this week's 2005 Experimental Biology conference add to the growing body of research that eating just a handful of almonds may be a valuable tool to combat some of America's leading health threats, including obesity, heart disease and diabetes.

6 Apr 2005

Britain becoming "pill for every ill" society

A report by the influential Commons Select Committee on Health, criticises the drugs industry for promoting the wider use of medication in a bid to increase its profits, and says Britain is being turned into "pill for every ill" society by the multibillion-pound drugs industry, which encourages patients to take medication even for "unhappiness".

5 Apr 2005

Statins, other cholesterol-depleting agents, may disrupt hypertension from developing

Cholesterol-lowering agents, such as the widely-prescribed statin drugs, and cholesterol-blocking agents may prove to be “novel therapeutic agents to modify cellular calcium that contributes to the development of pulmonary hypertension,” according Hemal H. Patel who lead a multidisciplinary team of researchers at the University of California, San Diego (UCSD).

3 Apr 2005

Simvastatin linked to protection against endothelial dysfunction in diabetic rats

Almost two years ago, the diabetes arm of the Heart Protection Study, the largest-ever study using a cholesterol-lowering medication, found that diabetics who took a daily dose of the statin drug simvastatin over five years reduced the risk of a first nonlethal heart attack by 37 percent and risk of a first nonfatal or fatal stroke by 24 percent, regardless of their cholesterol or glucose levels.

3 Apr 2005