Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Stem cells from umbilical cord blood, given intravenously with mannitol drug reduce stroke size and damage

Researchers first gave the drug, mannitol, to provide temporary passage through the blood-brain barrier then transfused human umbilical cord blood cells into a stroke animal model. When used in the first hours and days following a stroke, stroke size decreased by 40 percent and resulting disability was significantly reduced.

26 Sep 2004

First generation of human retinal cells in the laboratory from human embryonic stem cells

Some of these retinal tissues such as Retinal Pigment Epithelium (RPE) may provide a novel therapeutic strategy for such devastating diseases as macular degeneration, retinitis pigmentosa, and other retinal degenerative diseases.

23 Sep 2004

Data suggests potential role of Quadramet in conjunction with chemotherapy for the treatment of acute myeloid leukemia

Cytogen Corporation today announced the presentation of new data relating to its lead therapeutic product Quadramet (samarium Sm-153 lexidronam injection) during the 36th Congress of the International Society of Pediatric Oncology (SIOP).

20 Sep 2004

Research findings may help stave off full-blown diabetes

A new study by researchers at Joslin Diabetes Center sheds light on the key mechanisms by which new pancreatic beta cells normally form in response to insulin resistance. These findings may some day help researchers devise ways of staving off full-blown diabetes.

18 Sep 2004

Link between eosinophils and asthma

Mayo Clinic researchers have used a comparative genomic strategy to demonstrate a causative link between eosinophils, a rare type of white blood cell, and asthma.

18 Sep 2004

Potential stem cells treatment for retinitis pigmentosa and other retinal degenerations

A team of researchers from The Scripps Research Institute was able to preserve visual function in mice that were genetically predisposed to developing a profound degenerative disease that destroys their retinas.

16 Sep 2004

Stem cell science and orthopedic surgery may reduce failure rate in hip replacements

By combining stem cell science with orthopedic surgery, a team of researchers at the University of British Columbia and Vancouver Coastal Health Research Institute aims to reduce the 10 per cent failure rate in hip replacements and make repeat replacements and other joint repairs obsolete within 10-15 years.

16 Sep 2004

Role of gene identified in development of tumours in children

Medical researchers from Children’s Cancer Institute Australia for Medical Research (CCIA) have made significant progress in understanding tumour initiation in the aggressive, debilitating childhood cancer, neuroblastoma

14 Sep 2004

California Chamber of Commerce lends support to stem cell research

The California Chamber of Commerce has joined with a broad and growing coalition of business groups, patient advocates and medical organizations in endorsing a "YES" vote on Proposition 71, the California Stem Cell Research and Cures Initiative, on the November 2004 statewide ballot.

14 Sep 2004

Researchers have discovered a possible way to distinguish lethal from localized prostate cancers

If future studies show their test -- measuring the level of activity of a signaling pathway called Hedgehog -- can predict which prostate cancers will spread, the results could revolutionize decision making processes for prostate cancer patients, the researchers say.

13 Sep 2004

Pioneering work with human embryonic stem cells could speed up development of new treatments for Parkinson’s and diabetes

Pioneering work with human embryonic stem (hES) cells could speed up the development of new treatments for a range of degenerative disorders such as Parkinson’s disease and diabetes according to Dr Stephen Minger of King’s College London, speaking today at the BA Festival of Science.

8 Sep 2004

Pig tissue may help reduce the damage and disability of stroke

A tiny capsule containing tissue that secretes a cocktail of brain-nourishing neurotrophic factors may one day help reduce the damage and disability of stroke, according to research published in the September issue of Stroke.

7 Sep 2004

Scientists investigate the ability of heart muscle to repair itself

The scientists will investigate the ability of heart muscle to repair itself – after being damaged by a heart attack, for example – and to regain function.

6 Sep 2004

Hair growing stem cells may one day provide treatments for human hair conditions

Researchers at the Howard Hughes Medical Institute at The Rockefeller University have isolated stem cells from the skin of a mouse, and showed, for the first time, that an individual stem cell can renew itself in the laboratory and then be used in grafts to produce skin, hair and oil glands.

5 Sep 2004

Bone marrow produces cells that permanently heal wounds

Bone marrow produces cells that not only help fight infection but also permanently heal wounds, according to research at the University of Washington. Previously, researchers had not known that bone marrow contributed to the development of new skin in wounds.

5 Sep 2004

First Parkinson’s gene therapy patient well after 1 year suggesting that the therapy is safe and effective

The first ever patient to have undergone gene therapy for Parkinson’s appears to have come through phase I without a hitch, suggesting that the therapy is safe and effective, reports Marina Murphy in Chemistry & Industry.

2 Sep 2004

Royal Society calls for ban on human reproductive cloning

The Royal Society has called on the United Nations to introduce a ban on human reproductive cloning at its 59th General Session in October.

31 Aug 2004

Converting cells into heart muscle

This plasticity concept – the ability of bone marrow cell to transdifferentiate into heart muscle cell – is supported by experimental and clinical data. Another possibility is to replace the missing function by causing transdifferentiation of existing cells. Transdifferentiation means converting one sort of cell, e.g. fibroblast, into another, e.g. muscle cell.

30 Aug 2004

Surgeons remodel and replace man's jaw bone allowing him to eat first dinner in 9 years

“By the 4th week post-transplantation the patient enjoyed his first dinner in 9 years (bread and sausages); before reconstruction he had only been able to eat soft food and soup”.

26 Aug 2004

Study of new gene and cell therapy to better understand how genetically-engineered cells can help pace the heart

Guidant Corporation, Columbia University and Stony Brook University will collaborate to study a new gene and cell therapy that may ultimately provide better understanding of how genetically-engineered cells can help pace the heart.