Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Thalidomide shows promise in fighting myeloma

Thalidomide, a drug often used to treat symptoms of leprosy and in testing to fight HIV, is now demonstrating activity in fighting a common cancer that occurs in bone marrow, myeloma.

6 Dec 2004

New advances in sickle cell disease

Excruciating pain episodes, recurrent pneumonias, strokes, severe infections, chronic hemolytic anemia, and secondary pulmonary hypertension are common complications of sickle cell disease, a life-threatening inherited defect in blood that causes normally disc-shaped red blood cells to take on a sickle shape.

6 Dec 2004

Scientist develops way to deliver promising genetic tool into living cells

By exploiting an HIV protein that readily traverses cell membranes, Carnegie Mellon University scientists have developed a new way to introduce a gene-like molecule called a peptide nucleic acid (PNA) directly into live mammalian cells, including human embryonic stem (ES) cells.

6 Dec 2004

Heart Hospital begins experimental cell therapy

Physicians at the Heart Hospital became the first team in the UK to treat a patient with an experimental new therapy designed to repair damage to cardiac muscle resulting from a heart attack. If successful, this treatment would give doctors the ability to improve the hearts of people with heart failure, rather than just treating the symptoms.

6 Dec 2004

Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Modern research is delving deep into the human genome to find the answers to medical mysteries and, hopefully, cures for the most deadly diseases. According to four new studies presented during the 46th Annual Meeting of the American Society of Hematology

5 Dec 2004

Bcl-6 oncogene - genetic target for lymphoma treatment

Results from a pre-clinical study show that the gene designated Bcl-6 is an oncogene -- that is, one with the potential to cause a normal cell to become cancerous -- but that certain peptide inhibitors can in effect inactivate it, according to a study to be presented today during the 46th Annual Meeting of the American Society of Hematology (ASH).

5 Dec 2004

Single dose phase I data on CG53135 for the prevention of oral mucositis

CuraGen Corporation has announced results presented from a Phase I clinical trial with CG53135 for the prevention of oral mucositis (OM) in patients receiving high dose chemotherapy (HDCT) followed by autologous hematopoietic stem cell transplantation (AHSCT) at the ASH 46th Annual Meeting in San Diego, CA.

5 Dec 2004

Researchers are successfully treating incontinent women with the patient's own muscle-derived stem cells

Austrian researchers are successfully treating incontinent women with the patient's own muscle-derived stem cells. The findings of the first clinical study of its kind were presented today at the annual meeting of the Radiological Society of North America (RSNA).

29 Nov 2004

Scientists have induced human insulin-producing cells of the pancreas to revert to islet precursor cells

Scientists at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) have induced human insulin-producing cells of the pancreas to revert to islet precursor cells.

29 Nov 2004

Study finds that stomach cancer originates from bone marrow derived stem cells, rather than from stomach stem cells

A common assumption among cancer specialists is that most cancers originate from tissue stem cells – for example, the gastric stem cells contained in the lining of the stomach.

29 Nov 2004

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

A new study published in the New England Journal of Medicine confirms that stem cells derived from the umbilical cords of newborn babies are a viable and effective transplant source for thousands of leukemia patients who have no other treatment option.

24 Nov 2004

Cord blood registry sees FDA regulation as good for consumers and industry

Beginning in May 2005, cord blood banks must meet new federal safety standards mandated by the Food and Drug Administration (FDA).

24 Nov 2004

Scientists join forces to improve the effectiveness of a drug used to treat chronic myeloid leukaemia

Scientists from Glasgow and Liverpool are joining forces to improve the effectiveness of a drug used to treat a form of leukaemia, chronic myeloid leukaemia (CML), which affects 750 people in the UK each year.

24 Nov 2004

New mechanism that contributes to the development of some breast and ovarian cancers

Researchers at Mount Sinai School of Medicine have discovered a new mechanism of activation of a pathway known to be implicated in many cancers.

23 Nov 2004

New research may lead to new treatments for spinal cord injury and multiple sclerosis

For the first time, researchers have used human embryonic stem cells to create new insulating tissue for nerve fibers in a live animal model – a finding that has potentially important implications for treatment of spinal cord injury and multiple sclerosis.

23 Nov 2004

Stem cells' repair skills could be link to cancer

Johns Hopkins researchers say there is growing evidence that stem cells gone awry in their efforts to repair tissue damage could help explain why long-term irritation, such as from alcohol or heartburn, can create a breeding ground for certain cancers.

23 Nov 2004

Stem cells can preserve and improve vision in eyes damaged by retinal disease

"These findings hold great promise for potential treatments for people suffering from macular degeneration, diabetic retinopathy and other retinal diseases," says Michael Young, PhD, an assistant scientist at Schepens Eye Research Institute and the lead author of the study.

18 Nov 2004

Cells from skeletal muscle could be an important source of stem cells for repairing damaged muscle or nerve tissue

A group of cells called skeletal-muscle satellite cells are able to regenerate muscle fibres. Giulio Alessandri (Carlo Besta Neurological Institute, Milan, Italy) and colleagues investigated whether these cells can differentiate into different types of mesenchymal cell (the types of cell that eventually form connective tissue, bone, cartilage, and the circulatory and lymphatic systems).

18 Nov 2004

Heart bypass gets new source for replacement blood vessels

The search for a stable, renewable source of blood vessels, especially for potential use in heart bypass surgery, has reached a milestone at the State University of New York at Buffalo.

11 Nov 2004

Stem cell gene linked to a portion of one of the most common childhood brain cancers

Scientists at Johns Hopkins have linked a stem-cell gene to a portion of one of the most common childhood brain cancers, opening the door to tailored therapies that block the gene's tumor-promoting ability.

10 Nov 2004

Stem Cells News and Research

Further Reading

Thalidomide shows promise in fighting myeloma

New advances in sickle cell disease

Scientist develops way to deliver promising genetic tool into living cells

Heart Hospital begins experimental cell therapy

Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Bcl-6 oncogene - genetic target for lymphoma treatment

Single dose phase I data on CG53135 for the prevention of oral mucositis

Researchers are successfully treating incontinent women with the patient's own muscle-derived stem cells

Scientists have induced human insulin-producing cells of the pancreas to revert to islet precursor cells

Study finds that stomach cancer originates from bone marrow derived stem cells, rather than from stomach stem cells

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

Cord blood registry sees FDA regulation as good for consumers and industry

Scientists join forces to improve the effectiveness of a drug used to treat chronic myeloid leukaemia

New mechanism that contributes to the development of some breast and ovarian cancers

New research may lead to new treatments for spinal cord injury and multiple sclerosis

Stem cells' repair skills could be link to cancer

Stem cells can preserve and improve vision in eyes damaged by retinal disease

Cells from skeletal muscle could be an important source of stem cells for repairing damaged muscle or nerve tissue

Heart bypass gets new source for replacement blood vessels

Stem cell gene linked to a portion of one of the most common childhood brain cancers

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