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COVID-19 pandemic highlights the risk of using systemic corticosteroids

Healthcare workers in tropical and sub-tropical settings where strongyloidiasis is prevalent or caring for patients who have travelled to such areas, need to maintain a high level of awareness about the use of corticosteroids, including when this class of anti-inflammatories is given to patients suspected of infection with SARS-CoV-2.

17 Dec 2020

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

As researchers strive to find safe therapeutics for COVID 19, a study suggests that preventing the movement of cholesterol may inhibit viral entry by up to 80%.

17 Dec 2020

A battle-weary Seattle hospital fights the latest COVID surge

As hospitals across the country weather a surge of COVID-19 patients, in Seattle — an early epicenter of the outbreak — nurses, respiratory therapists and physicians are staring down a startling resurgence of the coronavirus that’s expected to test even one of the best-prepared hospitals on the pandemic’s front lines.

10 Dec 2020

Researchers develop new approach for COVID-19 testing

Researchers from UC San Francisco and the Chan Zuckerberg Biohub have developed a new approach for COVID-19 testing that detects a distinct pattern of immune gene expression in infected individuals.

7 Dec 2020

Study shows how parasite that causes Chagas disease resists current therapies

New insight on how a parasite can resist current therapies has been published today in the open-access eLife journal.

2 Dec 2020

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

A research team from Kumamoto University in Japan has found that the combination of weak pulsed electrical current and heat exerts anti-inflammatory and anti-fibrotic effects in the kidneys, as well as a protective effect against nephrotic syndrome (NS) by inhibiting apoptosis (cell death) of kidney cells.

30 Nov 2020

Potential treatment could reduce heart failure after a significant heart attack

While there are therapies to aid in overall heart health, there are very few preventative therapies for heart failure after a significant heart attack, a serious condition that has a very significant mortality.

24 Nov 2020

Masks can cause more problems in people with skin allergies

Throughout the course of the COVID-19 pandemic, those able to wear a face mask have been encouraged to do so to prevent transmission of the virus. For some people with skin allergies, wearing a mask can cause further problems.

17 Nov 2020

Corticosteroids can help in survival of elderly patients with severe COVID-19

A new study group based in France have looked at the rates of survival among elderly patients with COVID-19 who were administered with corticosteroids.

16 Nov 2020

New procedure offers lasting pain relief for patients with osteoarthritis

A novel outpatient procedure offers lasting pain relief for patients suffering from moderate to severe arthritis in their hip and shoulder joints, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA).

16 Nov 2020

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

Rather than life-threatening hyperinflammation, most adults with moderate-to-severe COVID-19 have a suppressed viral immune response when compared to adults with another viral respiratory infection, influenza. St. Jude Children's Research Hospital and Washington University School of Medicine in St. Louis led research that suggests most COVID-19 patients are not candidates for treatment with steroids such as dexamethasone.

16 Nov 2020

Study explains why anti-inflammatory drugs benefit only few people with severe COVID-19

The turning point for people with COVID-19 typically comes in the second week of symptoms. As most people begin to recover, a few others find it increasingly difficult to breathe and wind up in the hospital.

16 Nov 2020

Elastic-free facial masks could benefit individuals with contact dermatitis during COVID-19

A University of Cincinnati immunologist is recommending that individuals with contact dermatitis choose facial masks made without elastic or rubber that allow them to stay safe in the midst of COVID-19 while avoiding possible allergic reactions.

15 Nov 2020

HSS presents research related to rheumatology and orthopedic surgery at 2020 ACR annual meeting

At this year's American College of Rheumatology virtual meeting, Hospital for Special Surgery (HSS) presented exciting research related to rheumatology and orthopedic surgery.

10 Nov 2020

Study shows dexamethasone can reduce chance of COVID-19-related death

Research has shown that dexamethasone, a widely available steroid, can significantly reduce the chance of death from COVID-19.

10 Nov 2020

Oral methotrexate can be an effective intervention for people with knee OA

A new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of treatment with oral methotrexate, adults with primary knee osteoarthritis (OA) with inflammation had significant improvements in physical function and inflammation, a sign that this inexpensive, generic pill may be an important intervention for knee OA.

6 Nov 2020

Study highlights racial disparities in the care of patients with rheumatoid arthritis

A new study reveals that Black patients with rheumatoid arthritis (RA) were less likely to be prescribed a biologic treatment and more likely to use glucocorticoids, which carry a risk of serious long-term side effects.

6 Nov 2020

Corticosteroid injections for knee OA do not speed up the progression of disease

New research shows that corticosteroid injections for knee OA treatment do not hasten a patient's progression to a total knee replacement when compared with hyaluronic acid injections.

6 Nov 2020

Researchers identify a new way to prevent skin reactions in cancer patients

Using the body's immune system to fight cancer has great potential, but can also bring serious side effects, including itchy and painful skin reactions.

27 Oct 2020

Antenatal steroids improve preterm newborn survival in low-resource settings, finds study

The results of a new clinical trial, published today in the New England Journal of Medicine, show that dexamethasone- a glucocorticoid used to treat many conditions, including rheumatic problems and severe COVID-19- can boost survival of premature babies when given to pregnant women at risk of preterm birth in low-resource settings.

23 Oct 2020

Steroid News and Research

COVID-19 pandemic highlights the risk of using systemic corticosteroids

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

A battle-weary Seattle hospital fights the latest COVID surge

Researchers develop new approach for COVID-19 testing

Study shows how parasite that causes Chagas disease resists current therapies

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

Potential treatment could reduce heart failure after a significant heart attack

Masks can cause more problems in people with skin allergies

Corticosteroids can help in survival of elderly patients with severe COVID-19

New procedure offers lasting pain relief for patients with osteoarthritis

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

Study explains why anti-inflammatory drugs benefit only few people with severe COVID-19

Elastic-free facial masks could benefit individuals with contact dermatitis during COVID-19

HSS presents research related to rheumatology and orthopedic surgery at 2020 ACR annual meeting

Study shows dexamethasone can reduce chance of COVID-19-related death

Oral methotrexate can be an effective intervention for people with knee OA

Study highlights racial disparities in the care of patients with rheumatoid arthritis

Corticosteroid injections for knee OA do not speed up the progression of disease

Researchers identify a new way to prevent skin reactions in cancer patients

Antenatal steroids improve preterm newborn survival in low-resource settings, finds study

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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