Stunted Growth News and Research

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Study sheds light on oral vaccine failure in mouse model of chronic gut disorder

A chronic gut disorder that occurs in regions with poor sanitation disrupts intestinal immune responses and impairs oral vaccine effectiveness in a mouse model of the disease, according to research led by UPMC Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine scientists.

3 Aug 2021

Common cause of rare syndromes revealed by cultured mini-brains

The culprit behind a large number of cancerous tumors is known to be a certain protein. Now for the first time, research shows that the same protein is the cause of several rare brain syndromes.

24 Jun 2021

New low cost, non-electric warmer effectively treats infant hypothermia

Neonatal hypothermia -- which occurs when an infant's core body temperature falls below the normal range needed to maintain health -- contributes to approximately one million deaths each year, and countless cases of stunted growth, almost exclusively in low- and middle-income countries.

7 May 2021

New evidence supports ivermectin use in children weighing less than fifteen kilograms

Millions of children weighing less than 15kg are currently denied access to Ivermectin treatment due to insufficient safety data being available to support a change to the current label indication.

18 Mar 2021

New study shows link between intestinal microbiota and maternal behavior

As scientists learn more about the microorganisms that colonize the body--collectively called the microbiota--one area of intense interest is the effect that these microbes can have on the brain.

30 Jan 2021

Study sheds new light on the role of MLL4 gene in Kabuki syndrome

Scientists have known for years that mutations in the MLL4 gene can cause Kabuki syndrome, a rare developmental disorder.

11 Jan 2021

Gut cells alert the body to danger during parasite invasion

To effectively combat an infection, the body first has to sense it's been invaded, then the affected tissue must send out signals to corral resources to fight the intruder.

28 Dec 2020

Toxin produced by E. coli bacteria also has nondiarrheal effects on the digestive tract

For people in wealthy countries, diarrhea is usually nothing more than an uncomfortable inconvenience for a few days. But for a poor child in a developing country, repeated bouts of diarrhea can lead to serious health consequences such as malnutrition, stunted growth and cognitive deficits.

9 Dec 2020

Researchers identify new mechanism through which plants can regulate gene expression

Just like other organisms, plants must respond dynamically to a variety of cues over their lifetime. Going through different developmental stages, or altering their form in response to a drought or drastic temperature change requires altering which of their genes are expressed into proteins and when those processes occur.

8 Dec 2020

Vitamin D deficiency during early development can influence metabolic health

Using a zebrafish model, researchers from North Carolina State University have found that vitamin D deficiency during early development can disrupt the metabolic balance between growth and fat accumulation.

29 Sep 2020

Children born at high altitude smaller at birth and have stunted growth

A new study released this week by Ethiopian researchers shows that children who are born at higher altitudes, such as 1,500m (4,921 ft) above sea level, are more at risk of being smaller at birth and have a stunted growth compared to their counterparts born at lower altitudes. The research is published in the latest issue of the journal JAMA Pediatrics.

25 Aug 2020

Girls with anorexia nervosa can have stunted growth

Girls with anorexia nervosa can have stunted growth and may not reach their full height potential, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

20 Aug 2020

Persistent DNA damage in the placenta can affect embryonic growth

Scientists at the Stowers Institute for Medical Research have shown that a dysfunctional placenta can play a previously unrecognized role during the earliest stages of development in mouse models of Cornelia de Lange syndrome.

16 Jun 2020

Researchers analyze the scope of global childhood malnutrition

The scope of childhood malnutrition has decreased since 2000, although millions of children under five years of age are still undernourished and, as a result, have stunted growth.

2 Mar 2020

New mathematical technique describes the behavior of cellular enzymes

Everything a cell does, from dividing in two to migrating to a different part of the body, is controlled by enzymes that chemically modify other proteins in the cell.

13 Feb 2020

Low-protein diet throughout pregnancy and lactation may increase risk of liver damage

A study in rats examines a pathway through which protein deficiency during pregnancy leads to fat accumulation in the liver and increased risk of liver damage.

28 Jan 2020

Poorest countries have high levels of both obesity and malnutrition

Malnutrition involves consuming nutrients that are either too much or not enough in a way that it causes health problems. The health issue has been a longstanding predicament worldwide, and now, a new study shows that a third of the poorest countries in the world are facing high levels of obesity, as well as undernutrition.

16 Dec 2019

UMSOM researchers to test the safety, tolerability of prototype Shigella-ETEC vaccine

Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella and enterotoxigenic Escherichia coli, and researchers at the University of Maryland School of Medicine are testing a vaccine designed to offer protection against these serious pathogens.

10 Dec 2019