Super resolution microscopy News and Research

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Super-resolution tools have made it possible to break the diffraction barrier and resolve objects as small as 10-20 nm.

Scientists visualize diabetes-related proteins at high resolution

Scientists have examined a key receptor for the first time at high resolution - broadening understanding of how it might function, and opening the door to future improvements in treating conditions such as type 2 diabetes.

24 Jan 2020

Diabetes-related proteins seen in high-res for the first time

A team of researchers have reported, in an exciting study published in the journal Nature Communications, that they were able to examine an important receptor at high definition for the first time. This detailed visualization has helped them greatly to understand its mechanism of functioning. This could help develop better ways to treat Type 2 diabetes mellitus as well as other conditions.

23 Jan 2020

Researchers visualize molecular organization of TNFα receptor molecules

Whether a sick cell dies, divides, or travels through the body is regulated by a sophisticat-ed interplay of signal molecules and receptors on the cell membrane.

17 Jan 2020

Editor's Pick: Life Science Interviews from 2019

In this article, our editors look back at their favorite life science interviews from 2019.

17 Jan 2020

Discovery of 'cellular bike couriers' could shed light on disease spreading mechanisms

A previously unknown component of our cells that delivers proteins like a bike courier in heavy traffic could shed light on the mechanisms that allow cells to spread in diseases such as cancer.

31 Oct 2019

Researchers unveil ultrastructure of focal adhesion scaffold in pluripotent stem cells

Focal adhesions are known as signaling platforms broadcasting the information of the biochemical and physical qualities of the extracellular matrix into intracellular signaling cascades.

25 Oct 2019

Researchers discover how the body repairs damaged DNA

Researchers from the University of Copenhagen have made an extraordinary discovery in how the body repairs damaged DNA, which can lead to better understanding and management of diseases such as cancer.

25 Oct 2019

New technique can rapidly image synaptic proteins at high resolution

Our brains contain millions of synapses -- the connections that transmit messages from neuron to neuron. Within these synapses are hundreds of different proteins, and dysfunction of these proteins can lead to conditions such as schizophrenia and autism.

26 Sep 2019

New platform uses nanoparticles to deliver anti-cancer agent to cells

Scientists from the University of Cambridge have developed a platform that uses nanoparticles known as metal-organic frameworks to deliver a promising anti-cancer agent to cells.

16 Sep 2019

Super-resolution microscopy helps unravel elusive causes of dementia

University of Queensland researchers have used super-resolution microscopy to observe key molecules at work inside living brain cells, further unraveling the puzzle of memory formation and the elusive causes of dementia.

2 Aug 2019

Super-Resolution Raman Imaging with Plasmonic Substrates

Renee Frontiera discusses the development of a super-resolution Raman microscope that could one day supersede fluorescence-based super-resolution microscopes.

From Pittcon 14 Jun 2019

Study provides insight on how two proteins help influenza A virus to fight its way to cells

Researchers have provided new insight on how two proteins help influenza A virus particles fight their way to human cells.

16 May 2019

Researchers identify crucial player in controlling misfolded proteins

Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell and directs them towards disposal.

27 Mar 2019

Discovery of protein, lipid connection could lead to new influenza therapies

The connection between an influenza virus surface protein and a host cell lipid has been discovered by researchers at the University of Maine and the National Institutes of Health. Confirmation of direct interaction between the protein and lipid could lead to new antiviral therapies.

6 Mar 2019

Super-resolution microscopy could help better study single cells

For a better understanding of biological processes, researchers need to be able to ‘see’ the smallest components of individual cells, such as DNA, mRNA and proteins.

12 Feb 2019

A Light Source in Quantitative Analysis: What Role Does it Play?

In this interview, Claudia Jaffe discusses the importance of illuminators in microscopy and the different types of light used in life science research.

From Lumencor, Inc 7 Jan 2019

University of Wuerzburg implements new turnkey confocal imaging system

Technology innovators in super-resolution microscopy, Amsterdam-based Confocal.nl,reports on the implementation of a new turnkey confocal imaging system in the laboratory of Professor Markus Sauer at the University of Würzburg.

From Confocal.nl 29 Nov 2018

Researchers create photoswitchable fluorescent proteins with optical properties

Researchers developed fluorescent proteins that can be controlled by orange and green light. These proteins will help to study processes in living cells. The work was supported by Russian Science Foundation grant, and the results were published in Nature Methods.

28 Sep 2018

New discovery overturns centuries of thought about nature of kidney stones

A geologist, a microscopist and a doctor walk into a lab and, with their colleagues from across the nation, make a discovery that overturns centuries of thought about the nature and composition of kidney stones.

14 Sep 2018

VTCRI study may disrupt conventional understanding about how electrical activity travels in the heart

Scientists at the Virginia Tech Carilion Research Institute have found evidence that may disrupt conventional understanding about how electrical activity travels in the heart -; a discovery that potentially can lead to new insight into medical problems such as heart arrhythmia and sudden cardiac death.

27 Aug 2018