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What is the association between diabetes and SARS-CoV-2 infections?

Researchers explored whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can expedite or trigger the development of diabetes mellitus (DM).

15 Nov 2022

Do SSRIs lower the risk of long COVID?

Researchers conducted a retrospective study to determine whether SSRIs with immunomodulatory and antiplatelet properties can decrease the risk of post-acute sequelae of COVID-19 (PASC).

15 Nov 2022

Short-term outcomes in pregnant patients with COVID-19 who received nirmatrelvir–ritonavir treatment

Researchers investigated the short-term outcomes of treating pregnant patients exhibiting mild to moderate symptoms of COVID-19 with Paxlovid, which is a combination of the antivirals nirmatrelvir and ritonavir.

15 Nov 2022

Hemagglutinin stem immunogens may hold the key for broad protection against influenza A viruses

Researchers proposed that vaccines targeting the immunosubdominant yet conserved hemagglutinin (HA) stem could trigger broadly neutralizing antibodies (bnAbs) against influenza A viruses.

15 Nov 2022

Study points to a pathogenic role for compromised anti-SARS-CoV-2 responses in cerebrospinal fluid

Researchers used a high throughput systems serology method to compare serum and CSF samples from SARS-CoV-2 infected individuals with and without long COVID symptoms to determine changes in the SARS-CoV-2 humoral immune responses.

15 Nov 2022

Prevalence and severity of liver enzyme alterations in COVID-19 and association with patient-centered outcomes

Researchers examined the prevalence of changes in liver enzymes in COVID-19.

15 Nov 2022

The origin of COVID-19: wildlife trade rather than laboratory leak?

A recent opinion piece published in PNAS discussed the sequence of events concerning the COVID-19 pandemic to provide evidence against the alleged leak of SARS-CoV-2 and the Ebola virus from viral research laboratories in Wuhan, China, and West Africa, respectively.

15 Nov 2022

The impact of lung remodeling from prior helminth infection on SARS-CoV-2 disease pathogenesis

A recent study reported that helminth exposure enhances viral clearance and survival of mice challenged with SARS-CoV-2.

15 Nov 2022

Moderna's bivalent boosters trigger strong antibody response against latest subvariants

Moderna reports the efficacy of a bivalent COVID-19 vaccine booster dose.

14 Nov 2022

Exploring antiviral drug combinations for SARS-CoV-2 suppression

Researchers assessed the impact of drug combinations on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suppression.

14 Nov 2022

What was the global SARS-CoV-2 seroprevalence from January 2020 to April 2022?

Researchers assessed SARS-CoV-2 seroprevalence worldwide between January 2020 and April 2022.

14 Nov 2022

SARS-CoV-2 spike subunit conformation determines plasma-neutralizing activity triggered by COVID-19 vaccines and natural infection

In a new study, researchers evaluated the effect of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein conformation on S-directed neutralizing antibodies (nAbs).

14 Nov 2022

Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

A new paper introduces evidence of effective alleviation of disease severity using intravenous immunoglobulin (IVIg).

14 Nov 2022

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

Researchers investigated the early T cell responses during SARS-CoV-2 infections to understand the mechanisms of rapid clonal expansion that characterize the T cell responses to acute infections and vaccinations.

14 Nov 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

SARS-CoV-2 detected in white-tailed deer in Canada

Researchers investigated the detection of SARS-CoV-2 in white-tailed deer.

14 Nov 2022

The viral fitness and antigenic relationship among Omicron sublineages

Researchers used mouse models and human airway cell cultures to investigate the relative viral replication rates and cross-neutralization against SARS-CoV-2 Omicron sublineages.

14 Nov 2022

Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccines

Researchers compared the waning of vaccine-induced immunity from two and three doses of mRNA COVID-19 Pfizer-BioNTech vaccine BNT162b2 by conducting a repeated serological study to assess the prolonged humoral response.

14 Nov 2022

More adverse reactions following bivalent COVID-19 mRNA booster vaccine

A recent study posted to medRxiv* examined adverse reactions after administration of a bivalent BNT162b2 coronavirus disease 2019 (COVID-19) vaccine booster.

13 Nov 2022

Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provides improved protection against Omicron BA.5

In a recent study published in the Emerging Infectious Disease journal, researchers compared the neutralization associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.5 sublineage to Omicron BA.1/BA.2 sublineages among vaccinated and convalescent patients.

13 Nov 2022

Syndrome News and Research

What is the association between diabetes and SARS-CoV-2 infections?

Do SSRIs lower the risk of long COVID?

Short-term outcomes in pregnant patients with COVID-19 who received nirmatrelvir–ritonavir treatment

Hemagglutinin stem immunogens may hold the key for broad protection against influenza A viruses

Study points to a pathogenic role for compromised anti-SARS-CoV-2 responses in cerebrospinal fluid

Prevalence and severity of liver enzyme alterations in COVID-19 and association with patient-centered outcomes

The origin of COVID-19: wildlife trade rather than laboratory leak?

The impact of lung remodeling from prior helminth infection on SARS-CoV-2 disease pathogenesis

Moderna's bivalent boosters trigger strong antibody response against latest subvariants

Exploring antiviral drug combinations for SARS-CoV-2 suppression

What was the global SARS-CoV-2 seroprevalence from January 2020 to April 2022?

SARS-CoV-2 spike subunit conformation determines plasma-neutralizing activity triggered by COVID-19 vaccines and natural infection

Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

SARS-CoV-2 detected in white-tailed deer in Canada

The viral fitness and antigenic relationship among Omicron sublineages

Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccines

More adverse reactions following bivalent COVID-19 mRNA booster vaccine

Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provides improved protection against Omicron BA.5

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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