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Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

In a recent study published in the journal Molecular Therapy, researchers identified Bifonazole, an imidazole-based antifungal agent, to have potent activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using high-throughput screening of small molecules.

12 May 2022

Study shows link between abnormal blood clotting and impaired exercise capacity in people with long COVID

According to a study published today in Blood Advances, people suffering from long COVID may face an increased risk of abnormal blood clotting.

11 May 2022

The promise of RNA medicine is targeted and personalized

The development of messenger RNA (mRNA) vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has only increased the impetus in this field.

11 May 2022

Discovery of host co-factors necessary for SARS-CoV2 infection

A new study published in the journal EMBO Reports has reported on the shedding of two proteases, namely, ADAM10 and ADAM17, which aids in S protein-dependent molecular events.

11 May 2022

Researchers find gene that shapes mutation rate in mice

Every organism is born with a few mutations in their genome that differ genetically from both of their parents.

11 May 2022

Study modeling tumor evolution reveals a central tradeoff that could be exploited for cancer treatment

Though the mutations accumulated by cancer cells occur more or less randomly, certain regions of genes essential to cancer growth appear to be more frequently mutated than others in established tumors.

11 May 2022

Review portrays clinical journey of messenger RNA vaccines and mRNA-based therapies

Researchers reviewed messenger ribonucleic acid (mRNA) technology and highlighted its clinical applications.

11 May 2022

Effectiveness of COVID-19 monoclonal antibodies against SARS-CoV-2 Omicron variant

Researchers depicted the efficacy of the SARS-CoV-2 monoclonal antibodies (mAbs) against the SARS-CoV-2 Omicron variant.

11 May 2022

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

A new study explored key vaccine features which could help induce and preserve humoral immunity against SARS-CoV-2 infection.

11 May 2022

Susceptibility of four SARS-CoV-2 Omicron sub-lineages to vaccines and monoclonal antibodies

Researchers demonstrated that four SARS-CoV-2 Omicron sub-lineages, BA.1, BA.1.1, BA.2, and BA.3, are resistant to current COVID-19 vaccines and antibody therapeutics to varying extents.

11 May 2022

COVID-19-induced non-cell-autonomous anosmia

Researchers reported that SARS-CoV-2-induced anosmia was based on non-cell-independent processes.

11 May 2022

Exploring routine saliva testing for SARS-CoV-2 in children

The focus of a recent study was to implement a weekly SARS-CoV-2 saliva testing schedule in childcare centers.

11 May 2022

Deep learning reveals genetic determinants of COVID-19-associated mortality

In a recent study posted to the medRxiv* preprint server, researchers applied deep learning methods and identified genetic variants linked to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-caused mortality.

11 May 2022

COVID-19 and cerebral blood flow

In a recent study posted to the medRxiv* preprint server, researchers assessed the impact of coronavirus disease 2019 (COVID-19) on cerebral blood flow in infected patients.

10 May 2022

Growing long-COVID health care burden

In a recent study posted to the medRxiv* preprint server, researchers assessed the long coronavirus disease (COVID) health care burden in Ontario, Canada.

10 May 2022

Report highlights the need for an office to support autoimmune disease research across NIH institutes

While the quantity and quality of research that the National Institutes of Health (NIH) conducts on autoimmune diseases is impressive, a strategic plan and a well-funded office to support the coordination of all autoimmune disease research across NIH institutes and centers are needed, says a new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine.

10 May 2022

Study investigates antibody-mediated response against different SARS-CoV-2 variants

In a recent study posted to the bioRxiv* preprint server, researchers assessed the impact of coronavirus disease 2019 (COVID-19) on antibody-mediated immunity.

10 May 2022

Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

In a recent study posted to the bioRxiv* preprint server, researchers reported that nanoparticles could prevent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) cell entry.

10 May 2022

New Clinical Practice Resource released to guide the treatment of patients with hearing loss

The American College of Medical Genetics and Genomics has released a new Clinical Practice Resource that will help direct the treatment of patients with hearing loss: "Clinical Evaluation and Etiologic Diagnosis of Hearing Loss: A Clinical Practice Resource of the American College of Medical Genetics and Genomics."

10 May 2022

Study finds link between hippocampal defects and intellectual disability in children with Joubert Syndrome

An important link has been found between the intellectual disability experienced by children with the rare disease Joubert Syndrome (JS) and defects in the hippocampus.

10 May 2022

Syndrome News and Research

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

Study shows link between abnormal blood clotting and impaired exercise capacity in people with long COVID

The promise of RNA medicine is targeted and personalized

Discovery of host co-factors necessary for SARS-CoV2 infection

Researchers find gene that shapes mutation rate in mice

Study modeling tumor evolution reveals a central tradeoff that could be exploited for cancer treatment

Review portrays clinical journey of messenger RNA vaccines and mRNA-based therapies

Effectiveness of COVID-19 monoclonal antibodies against SARS-CoV-2 Omicron variant

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

Susceptibility of four SARS-CoV-2 Omicron sub-lineages to vaccines and monoclonal antibodies

COVID-19-induced non-cell-autonomous anosmia

Exploring routine saliva testing for SARS-CoV-2 in children

Deep learning reveals genetic determinants of COVID-19-associated mortality

COVID-19 and cerebral blood flow

Growing long-COVID health care burden

Report highlights the need for an office to support autoimmune disease research across NIH institutes

Study investigates antibody-mediated response against different SARS-CoV-2 variants

Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

New Clinical Practice Resource released to guide the treatment of patients with hearing loss

Study finds link between hippocampal defects and intellectual disability in children with Joubert Syndrome

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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