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Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

Researchers discuss the use of the isothiocyanate sulforaphane for the treatment of both SARS-CoV-2 and HCoV-OC43 infections.

30 Mar 2022

SARS-CoV-2 and pandemic chilblains

Researchers evaluate the pathophysiological relationship between COVID-19 and pandemic-associated chilblain lesions.

30 Mar 2022

COMBINEDBrain Biorepository: A comprehensive approach to speed research for rare diseases

COMBINEDBrain puts advocacy groups in the driver's seat in the race to cure rare neurodevelopmental diseases. Patient advocacy foundations representing more than thirty rare genetic neurodevelopmental disorders join forces as part of COMBINEDBrain to make it faster to do research on their disorders.

30 Mar 2022

NYU Langone joins NIH-sponsored program as leading center to discover new targets for autoimmune, inflammatory diseases

NYU Langone Health is joining a new National Institutes of Health (NIH)-sponsored program called Accelerating Medicines Partnership Autoimmune and Immune-Mediated Diseases (AMP AIM) as a leading center to discover new targets for therapy in these diseases.

30 Mar 2022

A summary of SARS-CoV-2 RNA-protein interactome studies

A new study summarized the importance of SARS-CoV-2 ribonucleic acid protein interactomes in the study of RNA viruses.

30 Mar 2022

Study identifies 10 new genetic regions linked with Brugada syndrome

A recent study published in Nature Genetics identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder associated with sudden death in young adults.

30 Mar 2022

ACE2 decoy receptor with robust neutralization against Omicron subvariants shows therapeutic potential

Researchers demonstrated the inhalation of an ACE2 decoy receptor, sACE22.v2.4-IgG1, increases survival and ameliorates lung injury in K18-hACE2 transgenic mice.

30 Mar 2022

Minimal system for SARS-CoV-2 based virus-like particle production to study viral assembly and entry

Researchers proposed an optimal system to generate SARS-CoV-2 virus-like particles for examining viral assembly and entry into target host cells.

30 Mar 2022

Researchers create method to track SARS-CoV-2 RBD binding in vivo

Researchers developed a method for tracking the binding of the receptor-binding domain of SARS-CoV-2 in vivo using genetically engineered extracellular vesicles that can migrate to ACE2 expressing cells.

30 Mar 2022

Study examines pediatric emergency department attendance trends during the first COVID-19 wave in Europe

Researchers investigated the impact of SARS-CoV-2 infection and the adoption of preventive measures in pediatric emergency department attendances in Europe.

30 Mar 2022

Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

A recent study analyzed the polymorphisms in the SARS-CoV-2 spike proteins' S1/S2 subunits.

30 Mar 2022

Antiviral functions of interferon regulatory factors during human coronavirus infection

Researchers assessed the roles of the interferon regulatory factors: IRF1, IRF3, and IRF7 in infections by human coronaviruses.

30 Mar 2022

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

30 Mar 2022

Study describes the identification of a SARS-CoV-2 variant that escapes detection by antigen tests

Researchers raised concerns that some SARS-CoV-2 variants can escape detection by antigen tests.

30 Mar 2022

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

A new study reported systemic and mucosal immunity against SARS-CoV-2 via intranasal delivery of a vaccine containing recombinant SARS-CoV-2 antigens, nucleocapsid, and spike subunit.

30 Mar 2022

Study shows that the SARS-CoV-2 envelope protein potently restricts HIV-1 infection

Researchers demonstrated that E proteins of β-coronaviruses could restrict HIV-1 infection.

30 Mar 2022

Engineering rotavirus-based vaccine vectors expressing SARS-CoV-2 spike epitopes

Researchers proposed rotavirus-based vaccine vectors with the potential for developing polyvalent vaccines targeting multiple enteric viruses, including SARS-CoV-2.

30 Mar 2022

The potential efficacy of nasal nanoparticle COVID-19 vaccines

The current paper reviews progress in this field regarding nasal nanoparticle vaccines for COVID-19.

30 Mar 2022

Study investigates whether coinfection with multiple SARS-CoV-2 variants exists in COVID-19 patients

A new study shows that multiple variants of this virus may coinfect the same patient, using both genomic sequencing data and computational models.

30 Mar 2022

Lung abnormalities may remain detectable long after COVID-19 pneumonia

Some people recovering from COVID-19 pneumonia have CT evidence of damage to their lungs that persists a full year after the onset of symptoms, according to a new study published in the journal Radiology.

30 Mar 2022

Syndrome News and Research

Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

SARS-CoV-2 and pandemic chilblains

COMBINEDBrain Biorepository: A comprehensive approach to speed research for rare diseases

NYU Langone joins NIH-sponsored program as leading center to discover new targets for autoimmune, inflammatory diseases

A summary of SARS-CoV-2 RNA-protein interactome studies

Study identifies 10 new genetic regions linked with Brugada syndrome

ACE2 decoy receptor with robust neutralization against Omicron subvariants shows therapeutic potential

Minimal system for SARS-CoV-2 based virus-like particle production to study viral assembly and entry

Researchers create method to track SARS-CoV-2 RBD binding in vivo

Study examines pediatric emergency department attendance trends during the first COVID-19 wave in Europe

Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

Antiviral functions of interferon regulatory factors during human coronavirus infection

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Study describes the identification of a SARS-CoV-2 variant that escapes detection by antigen tests

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

Study shows that the SARS-CoV-2 envelope protein potently restricts HIV-1 infection

Engineering rotavirus-based vaccine vectors expressing SARS-CoV-2 spike epitopes

The potential efficacy of nasal nanoparticle COVID-19 vaccines

Study investigates whether coinfection with multiple SARS-CoV-2 variants exists in COVID-19 patients

Lung abnormalities may remain detectable long after COVID-19 pneumonia

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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