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NIH scientists demonstrate efficient aerosol transmission of SARS-CoV-2 in hamsters

Researchers in the United States have demonstrated the efficient aerosol transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – in a hamster model.

29 Jul 2021

SARS-CoV-2 Beta variant marginally affects Pfizer vaccination efficacy in fully vaccinated

Researchers from Israel recently evaluated the efficacy of the Pfizer vaccine against the SARS-CoV-2 B.1.351 variant.

28 Jul 2021

Spike-containing virus-like particles induce robust sterilizing immunity against SARS-CoV-2 in macaques

A team of international scientists has recently developed virus-like particles (VLPs) by coating liposomes with the synthetic spike glycoprotein of SARS-CoV-2.

28 Jul 2021

How SARS-CoV-2 variants effect maternal infection and pregnancy

A new study focuses on the impact of SARS-CoV-2 on maternal and perinatal outcomes.

28 Jul 2021

Mass spectrometry used to develop N-glycosylation profiles for SARS-CoV-2 D614G

A new study has characterized and compared the N-glycosylation of the wild type (S-614D) and variant (S-614G) of SARS-CoV-2 S glycoproteins using MS techniques.

28 Jul 2021

A quantitative assessment of SARS-CoV-2 bioaerosol production

In an effort to improve the sensitivity and sample recovery of mask sampling, researchers developed a mask sampling tool to assess bioaerosol variation.

28 Jul 2021

Kids with allergies less likely to get SARS-CoV-2

Asthma is not associated with worse outcomes among children and adolescents with COVID-19.

28 Jul 2021

People with metabolic syndrome may be at higher risk for second stroke, death

People with larger waistlines, high blood pressure and other risk factors that make up metabolic syndrome may be at higher risk for having a second stroke and even dying than people who do not have metabolic syndrome, according to a meta-analysis published in the July 28, 2021, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Jul 2021

SARS-CoV-2 variants of concern employ different strategies of antibody escape

A recent study in the field of fluid analysis reveals a diverse set of strategies utilized by alpha and beta variants of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) in order to evade antibodies generated during an earlier infection with this virus. The paper is currently available on the bioRxiv* preprint server while it undergoes a peer-review process.

28 Jul 2021

How do people with post acute sequelae of COVID-19 react to SARS-CoV-2 vaccines?

A new study focuses on the impact of vaccines on the changes in the symptoms in the PASC group.

27 Jul 2021

Immunity to SARS-CoV-2 in renal transplant and dialysis patients using Pfizer/BioNTech and Moderna vaccines

A study analyzes the immune responses of medical personnel, as well as immunocompromised DP and immunosuppressed KTR patients.

27 Jul 2021

SARS-CoV-2 spike-specific antibodies induced in breast milk by COVID-19 vaccines

An interesting new paper examines how these vaccines can help young patient populations to withstand the virus.

27 Jul 2021

Study suggests mRNA SARS-CoV-2 vaccines remain effective against variants

A study reports that many VOCs are associated with impaired reduction in their susceptibility to neutralization by COVID-19 vaccines.

27 Jul 2021

Impaired immune response to SARS-CoV-2 mRNA vaccination in immunocompromised patients

A new study describes how immunocompromised vaccine recipients may not always respond as expected to the COVID-19 vaccine.

27 Jul 2021

Return to play can be managed for athletes with genetic heart diseases, study suggests

Receiving the diagnosis of a genetic heart disease such as long QT syndrome, which can cause sudden cardiac death, has long been a game-ender for young athletes. But a 20-year study at Mayo Clinic following such athletes who were allowed to return to play suggests that the risks can be managed through a shared decision-making process.

27 Jul 2021

Study shows inhalable nanocatchers can protect lung cells against SARS-CoV-2

Inhalable nanocatchers that contain hACE2 have been recently developed by a group of researchers, providing a plethora of potential benefits in comparison to existing treatments against COVID-19.

27 Jul 2021

A new screening system to give insights into autistic adults' perspective taking difficulties

Autistic adults may have different behaviours or perspectives in the workplace or in social situations which may lead them into compromised situations.

27 Jul 2021

Monoclonal antibody CT-P59 demonstrates potent antiviral efficacy against SARS-CoV-2 delta variant

A Korean study has recently demonstrated antiviral potency of monoclonal antibody CT-P59 against the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The experiments conducted in animals infected with the delta variant have shown that CT-P59 is able to reduce symptom intensity and viral replication in the respiratory tract. The study is currently available on the bioRxiv* preprint server.

27 Jul 2021

Scientists identify an antiviral metabolite as a potential serum biomarker for SARS-CoV-2 infection

Scientists from the UK have recently identified an antiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine as a potential serum biomarker to diagnose active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the medRxiv* preprint server while awaiting peer review.

27 Jul 2021

SARS-CoV-2 interacts with unusual RNA structures in human cells

The study, published in the journal Nucleic Acids Research, demonstrated that G4 ligands, the chemical that binds with G4s, prevent this interaction. The results could pave the way for developing inhibitors of these interactions as potential antiviral compounds.

26 Jul 2021

Syndrome News and Research

NIH scientists demonstrate efficient aerosol transmission of SARS-CoV-2 in hamsters

SARS-CoV-2 Beta variant marginally affects Pfizer vaccination efficacy in fully vaccinated

Spike-containing virus-like particles induce robust sterilizing immunity against SARS-CoV-2 in macaques

How SARS-CoV-2 variants effect maternal infection and pregnancy

Mass spectrometry used to develop N-glycosylation profiles for SARS-CoV-2 D614G

A quantitative assessment of SARS-CoV-2 bioaerosol production

Kids with allergies less likely to get SARS-CoV-2

People with metabolic syndrome may be at higher risk for second stroke, death

SARS-CoV-2 variants of concern employ different strategies of antibody escape

How do people with post acute sequelae of COVID-19 react to SARS-CoV-2 vaccines?

Immunity to SARS-CoV-2 in renal transplant and dialysis patients using Pfizer/BioNTech and Moderna vaccines

SARS-CoV-2 spike-specific antibodies induced in breast milk by COVID-19 vaccines

Study suggests mRNA SARS-CoV-2 vaccines remain effective against variants

Impaired immune response to SARS-CoV-2 mRNA vaccination in immunocompromised patients

Return to play can be managed for athletes with genetic heart diseases, study suggests

Study shows inhalable nanocatchers can protect lung cells against SARS-CoV-2

A new screening system to give insights into autistic adults' perspective taking difficulties

Monoclonal antibody CT-P59 demonstrates potent antiviral efficacy against SARS-CoV-2 delta variant

Scientists identify an antiviral metabolite as a potential serum biomarker for SARS-CoV-2 infection

SARS-CoV-2 interacts with unusual RNA structures in human cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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