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Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research

Experiments involving animals and human cells conducted at the University of São Paulo (USP) in Brazil suggest that niclosamide, an anthelmintic widely used against tapeworms, effectively inhibits SARS-CoV-2 replication as well as the exacerbated inflammatory response that leads to death in many patients with severe COVID-19.

21 Oct 2022

Neuropharmacologist investigates plant-based treatments for epilepsy caused by pork tapeworms

Pork tapeworms are responsible for between 30 and 70 per cent of epilepsy cases around the world. According to the World Health Organization, the majority of people living with epilepsy can be found in low-income countries, mostly among subsistence farming communities.

19 Nov 2021

New compound inspired by tapeworm drugs shows two-pronged effectiveness against COVID-19

A group of medications long prescribed to treat tapeworm has inspired a compound that shows two-pronged effectiveness against COVID-19 in laboratory studies, according to a new publication appearing online in the journal ACS Infectious Disease.

9 Aug 2021

Is niclosamide a potential SARS-CoV-2 antiviral inhibitor?

Niclosamide is an antihelminthic drug, historically used to treat tapeworm infestations, though has been investigated and repurposed for use against SARS-CoV-2. In a new study recently uploaded to the preprint server bioRxiv* by Garrett et al. (July 12, 2021), the drug demonstrates the ability to reorganize the lipid profile of SARS-CoV-2 infected Vero E6 cells, thereby limiting virus replication.

14 Jul 2021

Researchers identify four substances that inhibit SARS-CoV-2 replication in cells

Researchers from the German Center for Infection Research at Charité - Universitätsmedizin Berlin and the University of Bonn have examined the way in which SARS-CoV-2 reprograms the metabolism of the host cell in order to gain an overall advantage.

21 Jun 2021

Tapeworm infection drug blocks SARS-CoV-2 damage in the lungs

New research published in the journal Nature found the presence of SARS-CoV-2 in the lungs resulted in abnormal pneumocytes and spike protein-mediated cell fusion. Their findings also showed that TMEM16F protein activation induces cell fusion. Therefore, drugs inhibiting the TMEM16F/Anoctamin6 calcium-activated ion channel, such as niclosamide, could serve as potential treatments for reducing the severity of COVID-19 infection.

12 Apr 2021

Research shows intestinal parasite infestations reduce COVID-19 severity

Now, new research out of Mekelle, Ethiopia, examines the role of parasitic infestation on the prognosis of COVID-19. The research paper, which appears on the preprint server medRxiv, shows that intestinal parasitosis is protective against severe COVID-19.

4 Feb 2021

Invasive alien species threaten biological diversity, shows study

The raccoon, raccoon dog, mink, and golden jackal are not native to Germany or Europe but are increasingly spreading in these non-native regions.

8 Dec 2020

Bayer supports WHO through donated medicines for treatment of T. solium infection

A recent agreement between the World Health Organization and the German pharmaceutical company Bayer promises hope of expanding access to essential medicines for the treatment of people exposed to or infected by the pork tapeworm Taenia solium.

12 Aug 2020

Scientists track down a potential target for new sleeping sickness drugs

Using ultra-bright X-ray flashes, a team of researchers has tracked down a potential target for new drugs against sleeping sickness: The scientists have decoded the detailed spatial structure of a vital enzyme of the pathogen, the parasite Trypanosoma brucei.

30 Jan 2020

Tapeworms need their head for stem cell-driven regeneration

Scientists have identified the stem cells that allow tapeworms to regenerate and found that their location in proximity to the head is essential, according to a new study in eLife.

24 Sep 2019

Parasites could have originated from transmissable cancers

Researchers have presented a controversial new theory suggesting that transmissible cancers could eventually evolve into their own multicellular species.

29 Aug 2019

New research aims to turn worms against parasite-associated cancer

Billions worldwide are infected with tropical worms. Unsurprisingly, most of these people live in poor countries, kept poor by the effects of worm-related malnourishment.

26 Mar 2019

Parasite egg DNA from ancient latrines shows people's diets from 500 B.C. to 1700 A.D.

Researchers from University of Copenhagen and Aarhus University have studied the DNA from the parasite eggs that are recovered from the faeces samples in ancient times.

26 Apr 2018

Parasitic tapeworm could someday help prevent or treat pediatric IBD

New research suggests that parasitic worms could someday help prevent or treat pediatric inflammatory bowel disease (IBD). The study, published ahead of print in the American Journal of Physiology-Gastrointestinal and Liver Physiology, was chosen as an APSselect article for March.

2 Mar 2018

Expert advice for the corporate titans taking on health care

An announcement Tuesday by three of the nation's corporate titans — Amazon, Berkshire Hathaway and JPMorgan Chase & Co. — that they are joining forces to address the high costs of employee health care has stirred the health policy pot. It immediately sent shock waves through the health sector of the stock market and reinvigorated talk about health care technology, value and quality.

31 Jan 2018

Tapeworm News and Research

Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research

Neuropharmacologist investigates plant-based treatments for epilepsy caused by pork tapeworms

New compound inspired by tapeworm drugs shows two-pronged effectiveness against COVID-19

Is niclosamide a potential SARS-CoV-2 antiviral inhibitor?

Researchers identify four substances that inhibit SARS-CoV-2 replication in cells

Tapeworm infection drug blocks SARS-CoV-2 damage in the lungs

Research shows intestinal parasite infestations reduce COVID-19 severity

Invasive alien species threaten biological diversity, shows study

Bayer supports WHO through donated medicines for treatment of T. solium infection

Scientists track down a potential target for new sleeping sickness drugs

Tapeworms need their head for stem cell-driven regeneration

Parasites could have originated from transmissable cancers

New research aims to turn worms against parasite-associated cancer

Parasite egg DNA from ancient latrines shows people's diets from 500 B.C. to 1700 A.D.

Parasitic tapeworm could someday help prevent or treat pediatric IBD

Expert advice for the corporate titans taking on health care

Tapeworm drug could provide new hope for patients with Parkinson's disease

Anti-parasite drug acts like tailored medicine against colon, prostate cancer

Oropouche virus could cause serious public health problem in Brazil, researcher warns

WHO marching toward extraordinary progress against neglected tropical diseases, report reveals

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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