Telomerase News and Research

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UGA discovery could lead to new ways to attack cancers by blocking their ability to grow

Human cancer cells divide and conquer. Unless physicians can control that division with surgery, chemotherapy or radiation, the wildly dividing cells will eventually destroy a person's life.

10 Jul 2008

Nanoparticles detect telomerase activity

Telomerase, an enzyme that prevents chromosomes from shortening when they divide, is widely suspected of playing a key role in making cancer cells immortal.

9 Jul 2008

Researchers find way to make tumor cells more sensitive to hyperthermia-enhanced radiation therapy

Tumors have a unique vulnerability that can be exploited to make them more sensitive to heat and radiation, researchers at Washington University School of Medicine in St. Louis report.

6 May 2008

Geron Corporation awarded UK grant funding for human embryonic stem cell research

Geron Corporation announced today two grant awards to the University of Edinburgh from the UK Stem Cell Foundation, with funding from the Medical Research Council and Scottish Enterprise.

6 May 2008

Menstrual blood - an abundant sources of stem cells

Researchers seeking new and more abundant sources of stem cells for use in regenerative medicine have identified a potentially unlimited, noncontroversial, easily collectable, and inexpensive source - menstrual blood.

23 Apr 2008

Researchers study Rituximab's action on cancer stem cells

Preliminary data from one of the first clinical trials to test a stem cell-targeting drug in cancer patients shows that while the drug did not prolong survival, its suppressing effect on patients' stem cells was impressive enough to send investigators looking for a better drug to try.

13 Apr 2008

Stanford researchers unmask proteins in telomerase

One of the more intriguing workhorses of the cell, a protein conglomerate called telomerase, has in its short history been implicated in some critical areas of medicine including cancer, aging and keeping stem cells healthy.

24 Mar 2008

New method for detecting HER2 breast cancer

Generations of mothers have served up chicken soup to remedy the common cold, but now the therapeutic fowl may find use in diagnosis as well.

21 Feb 2008

Scientists identifiy elusive telomere RNA subunit in single cell model

The Stowers Institute's Baumann Lab has identified the long-sought telomerase RNA gene in a single-cell research model.

28 Dec 2007

Telomerase enzyme structure provides significant new target for anti-cancer therapies

Inappropriate activation of a single enzyme, telomerase, is associated with the uncontrollable proliferation of cells seen in as many as 90 percent of all of human cancers. Since the mid-1990s, when telomerase was first identified in human tumors, scientists have eyed the enzyme as an ideal target for developing broadly effective anti-cancer drugs.

14 Nov 2007

Trop-2 new target for anti-tumour therapy in cancer

Italian scientists announced (Monday September 24) that they have found a new and promising target for anti-tumour therapy in cancer.

25 Sep 2007

Chronic stress can steal years from caregivers' lifetimes

The chronic stress that spouses and children develop while caring for Alzheimer's disease patients may shorten the caregivers' lives by as much as four to eight years, a new study suggests.

18 Sep 2007

New clues to why persistent acid reflux can turn into cancer

New research from scientists at UT Southwestern Medical Center and the Dallas Veterans Affairs Medical Center underscores the importance of preventing recurring acid reflux while also uncovering tantalizing clues on how typical acid reflux can turn potentially cancerous.

13 Aug 2007

Why acid reflux sometimes turns into cancer

12 Aug 2007

Mutations in a gene that helps regulate cell division linked to inherited form of fatal lung disease

Mutations in a gene that helps regulate cell division are responsible for some inherited cases of a fatal lung disease, researchers at UT Southwestern Medical Center have found.

27 Apr 2007

Johns Hopkins team stops form of blood cancer in its tracks

A Johns Hopkins team has stopped in its tracks a form of blood cancer in mice by engineering and inactivating an enzyme, telomerase, thereby shortening the ends of chromosomes, called telomeres.

26 Apr 2007

Genetic culprits of idiopathic pulmonary fibrosis

Scientists at Johns Hopkins have identified the genetic culprits that trigger a hereditary form of a fatal lung disease.

30 Mar 2007

Scientists step closer to understanding the relationship between aging and cancer

Wielding a palette of chromosome paints, scientists at the Salk Institute for Biological Studies have taken a step closer to understanding the relationship between aging and cancer by visualizing chromosomes of cells from patients with a heritable premature aging disease known as Werner Syndrome.

6 Feb 2007

New target for cancer therapy identified by Australian researchers

A new target for cancer therapy has been identified by Monash University scientists investigating the cell signalling pathways that turn on a gene involved in cancer development.

21 Sep 2006

The heart can heal itself

World Congress of Cardiology Report - Despite the dramatic advances in the care of patients with cardiovascular diseases that have occurred in the second half of the 20th century, heart failure (HF) is the most common cause of death in developed nations.

5 Sep 2006