Telomerase News and Research

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Klotho levels and telomere length may be associated through a coordinated downregulation of longevity factors

A new research paper was published by Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) in Volume 15, Issue 15, entitled, "Associations between klotho and telomere biology in high stress caregivers."

17 Aug 2023

Can epigenetic changes explain the strong link between age and cancer?

Researchers reported the link between aging, cancer, and epigenomic changes.

26 Jul 2023

An evaluation of the main nanotechnology approaches to improve the therapeutic potential of polyphenols against cancer

Researchers comprehensively evaluated all nanotechnology-based approaches.

18 Jul 2023

Quantum medicine: the way forward?

Study examines how quantum physics can contribute to medicine.

7 Jul 2023

Study reveals a link between short telomeres in ATII cells and lung fibrosis in post-COVID-19 patients

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 11, entitled, "Short telomeres in alveolar type II cells associate with lung fibrosis in post COVID-19 patients with cancer."

15 Jun 2023

Obesity strikes below the belt: Study reveals link between obesity and male infertility

The influence of obesity on male fertility is still under debate. In the present investigation, researchers scrutinized semen samples from both obese individuals and those of normal weight. The aim was to explore the relationship between obesity, the length of sperm telomeres, levels of mRNA associated with autophagy, and diverse semen characteristics.

29 May 2023

Researchers explore the possibility of treating lung cancer by targeting telomeres

Healthy cells can only divide a limited number of times during an organism's lifetime. In contrast, tumor cells are immortal: they proliferate indefinitely and uncontrollably, and this is the defining characteristic of cancer.

26 May 2023

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including the most common type of head and neck cancer, and elevated levels of white blood cells that produce antibodies within tumors.

13 Mar 2023

Latest Nobel Collection features five new science articles for young people

Frontiers for Young Minds, a unique, completely free kids’ science journal launched its second Nobel Collection today. It features five new articles in which top scientists connected directly with young reviewers to ensure their articles are clear, educational, and fascinating to read for young people before they were published in the journal.

3 Feb 2023

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Many public health warnings have been issued against alcohol consumption, even in small quantities, though the evidence for such strict limits is controversial. The current study, published in the MDPI journal Nutrients, is a narrative review focused on clearing up some of the confusion associated with alcoholic drinks.

4 Jan 2023

Pitt scientists solve the mystery of how melanoma tumors control their mortality

Scientists at the University of Pittsburgh School of Medicine have discovered the missing puzzle piece in the mystery of how melanoma tumors control their mortality.

10 Nov 2022

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Impaired DNA repair capacity among elderly increases expression of ACE2 receptor.

26 Oct 2022

ASU scientists discover an unusual RNA biogenesis pathway

For the very first time, a study led by Julian Chen and his group in Arizona State University's School of Molecular Sciences and the Biodesign Institute's Center for the Mechanism of Evolution, has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA).

3 Oct 2022

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Researchers described a novel antiviral mechanism of action for an FDA (food and drug administration)-approved thiopurine known as 6-thioguanine (6-TG).

21 Sep 2022

Study finds telomeres can set damage thresholds for cancer cells above which they cannot continue to divide

A recent study hypothesized that ALT might compromise telomere integrity if not restricted appropriately.

21 Sep 2022

Cell's anti-aging structures can set the damage threshold a cancer cell can sustain, study shows

A new study led by Claus M. Azzalin, group leader at Instituto de Medicina Molecular João Lobo Antunes- iMM and published today in the prestigious scientific journal Proceedings of the National Academy of Sciences (PNAS) shows, for the first time, that the cell's anti-aging structures – the telomeres – can set the damage threshold a cancer cell can sustain and above which cells cannot continue to divide and die.

20 Sep 2022

New mechanism may prevent the natural aging of immune cells

A new mechanism that slows down and may even prevent the natural aging of immune cells – one of the nine 'hallmarks of aging' – has been identified by an international team led by UCL scientists.

15 Sep 2022

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

In a study recently published in Cancer Research, a journal of the American Association for Cancer Research, a team of researchers led by C. Patrick Reynolds, M.D., Ph.D., director for the Texas Tech University Health Sciences Center School of Medicine Cancer Center, sought to expand upon his lab's previous research that showed ALT tumors identified by a biomarker known as C-circles share a common biology that confers vulnerabilities to be exploited for cancer therapy.

10 Aug 2022

Study focuses on how telomerase activity affects the regenerative potential of stem cells in human urine

The Wake Forest Institute for Regenerative Medicine researchers who were the first to identify that stem cells in human urine have potential for tissue regenerative effects, continue their investigation into the power of these cells.

28 Jun 2022

Mice live longer with nasal gene therapy

In a recent study published in the Proceedings of the National Academy of Sciences journal, researchers assessed the efficiency of a novel intranasal and injectable therapy in improving life expectancy.

17 May 2022